Product References
Immunostimulatory effects of a subcritical water extract of Ganoderma.
Biomedical reports
Hattori K,Takagi H,Ogata Y,Yamada T,Horiba H,Fukata K,Sakaida T,Yashiro Y,Hasegawa S,Tanaka H
13-5931-82 was used in Flow cytometry/Cell sorting to demonstrate that Ganoderma (SWEG) increased hematopoietic precursor cells, immature B cells, and NK cells in the bone marrow, and T cells in the thymus.
Sun Jan 01 00:00:00 EST 2023
Clonal lineage tracing reveals shared origin of conventional and plasmacytoid dendritic cells.
Immunity
Feng J,Pucella JN,Jang G,Alcántara-Hernández M,Upadhaya S,Adams NM,Khodadadi-Jamayran A,Lau CM,Stoeckius M,Hao S,Smibert P,Tsirigos A,Idoyaga J,Reizis B
13-5931-82 was used in Flow cytometry/Cell sorting to reveal the shared origin of pDCs and cDCs and suggest a revised scheme of DC development whereby pDCs share clonal relationship with cDC1s.
Tue Mar 08 00:00:00 EST 2022
Nonredundancy of IL-1α and IL-1β is defined by distinct regulation of tissues orchestrating resistance versus tolerance to infection.
Science advances
Eislmayr K,Bestehorn A,Morelli L,Borroni M,Vande Walle L,Lamkanfi M,Kovarik P
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunohistochemistry
Fri Mar 04 00:00:00 EST 2022
MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism.
Cancer cell
Ueda K,Kumari R,Schwenger E,Wheat JC,Bohorquez O,Narayanagari SR,Taylor SJ,Carvajal LA,Pradhan K,Bartholdy B,Todorova TI,Goto H,Sun D,Chen J,Shan J,Song Y,Montagna C,Xiong S,Lozano G,Pellagatti A,Boultwood J,Verma A,Steidl U
13-5931-82 was used in Flow cytometry/Cell sorting to identify MDMX overexpression as a pervasive preleukemic-to-AML transition mechanism in different genetically driven disease subtypes, and reveal Wnt/β-Catenin as a non-canonical MDMX-driven pathway with therapeutic potential for progression prevention and cancer interception.
Mon Apr 12 00:00:00 EDT 2021
Bone marrow adipogenic lineage precursors promote osteoclastogenesis in bone remodeling and pathologic bone loss.
The Journal of clinical investigation
Yu W,Zhong L,Yao L,Wei Y,Gui T,Li Z,Kim H,Holdreith N,Jiang X,Tong W,Dyment N,Liu XS,Yang S,Choi Y,Ahn J,Qin L
13-5931 was used in Flow cytometry/Cell sorting to identify MALPs as a critical player in controlling bone remodeling during normal bone metabolism and pathological bone loss in a RANKL-dependent fashion.
Tue Jan 19 00:00:00 EST 2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
RIPK3 Facilitates Host Resistance to Oral Toxoplasma gondii Infection.
Infection and immunity
Cervantes PW,Martorelli Di Genova B,Erazo Flores BJ,Knoll LJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunohistochemistry
Fri Apr 16 00:00:00 EDT 2021
Effects of signaling pathway inhibitors on hematopoietic stem cells.
Molecular medicine reports
Jiang Y,Xu Z,Ma N,Yin L,Hao C,Li J
13-5931 was used in Flow cytometry/Cell sorting to determine the effect of HDACs, mTOR, GSK‚3β and p38MAPK inhibitor combinations on the efficient expansion of HSCs using flow cytometry.
Fri Jan 01 00:00:00 EST 2021
BRD4-mediated repression of p53 is a target for combination therapy in AML.
Nature communications
Latif AL,Newcombe A,Li S,Gilroy K,Robertson NA,Lei X,Stewart HJS,Cole J,Terradas MT,Rishi L,McGarry L,McKeeve C,Reid C,Clark W,Campos J,Kirschner K,Davis A,Lopez J,Sakamaki JI,Morton JP,Ryan KM,Tait SWG,Abraham SA,Holyoake T,Higgins B,Huang X,Blyth K,Copland M,Chevassut TJT,Keeshan K,Adams PD
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Mon Jan 11 00:00:00 EST 2021
Design, Synthesis and Biological Evaluation of Arylpyridin-2-yl Guanidine Derivatives and Cyclic Mimetics as Novel MSK1 Inhibitors. An Application in an Asthma Model.
Molecules (Basel, Switzerland)
Bollenbach M,Nemska S,Wagner P,Camelin G,Daubeuf F,Obrecht A,Villa P,Rognan D,Bihel F,Bourguignon JJ,Schmitt M,Frossard N
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Wed Jan 13 00:00:00 EST 2021
IFNγ-Producing γ/δ T Cells Accumulate in the Fetal Brain Following Intrauterine Inflammation.
Frontiers in immunology
Lewis EL,Tulina N,Anton L,Brown AG,Porrett PM,Elovitz MA
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Wed Jan 05 00:00:00 EST 2022
Lung mesenchymal stromal cells influenced by Th2 cytokines mobilize neutrophils and facilitate metastasis by producing complement C3.
Nature communications
Zheng Z,Li YN,Jia S,Zhu M,Cao L,Tao M,Jiang J,Zhan S,Chen Y,Gao PJ,Hu W,Wang Y,Shao C,Shi Y
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Wed Oct 27 00:00:00 EDT 2021
Retinoic Acid Inhibits Tumor-Associated Mesenchymal Stromal Cell Transformation in Melanoma.
Frontiers in cell and developmental biology
Lou Q,Zhao M,Xu Q,Xie S,Liang Y,Chen J,Yuan L,Wang L,Jiang L,Mou L,Lin D,Zhao M
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Sat Apr 24 00:00:00 EDT 2021
Comprehensive mutagenesis identifies the peptide repertoire of a p53 T-cell receptor mimic antibody that displays no toxicity in mice transgenic for human HLA-A*0201.
PloS one
Trenevska I,Anderson AP,Bentley C,Hassanali T,Wiblin S,Maguire S,Pezzella F,Banham AH,Li D
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Wed Sep 29 00:00:00 EDT 2021
Abraxane-induced bone marrow CD11b+ myeloid cell depletion in tumor-bearing mice is visualized by μPET-CT with 64Cu-labeled anti-CD11b and prevented by anti-CSF-1.
Theranostics
Cao Q,Huang Q,Wang YA,Li C
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Fri Jul 23 00:00:00 EDT 2021
SPARC regulation of PMN clearance protects from pristane-induced lupus and rheumatoid arthritis.
iScience
Sangaletti S,Botti L,Gulino A,Lecis D,Bassani B,Portararo P,Milani M,Cancila V,De Cecco L,Dugo M,Tripodo C,Colombo MP
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunohistochemistry
Fri Jun 25 00:00:00 EDT 2021
Single-cell analyses unravel cell type-specific responses to a vitamin D analog in prostatic precancerous lesions.
Science advances
Abu El Maaty MA,Grelet E,Keime C,Rerra AI,Gantzer J,Emprou C,Terzic J,Lutzing R,Bornert JM,Laverny G,Metzger D
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Thu Jul 01 00:00:00 EDT 2021
Polyamines drive myeloid cell survival by buffering intracellular pH to promote immunosuppression in glioblastoma.
Science advances
Miska J,Rashidi A,Lee-Chang C,Gao P,Lopez-Rosas A,Zhang P,Burga R,Castro B,Xiao T,Han Y,Hou D,Sampat S,Cordero A,Stoolman JS,Horbinski CM,Burns M,Reshetnyak YK,Chandel NS,Lesniak MS
13-5931-82 was used in FC/FACS to indicate that polyamines are used by glioblastoma TAMCs to maintain normal intracellular pH and cell survival and thus promote immunosuppression during tumor evolution.
Mon Feb 01 00:00:00 EST 2021
TNF-α-induced alterations in stromal progenitors enhance leukemic stem cell growth via CXCR2 signaling.
Cell reports
Agarwal P,Li H,Choi K,Hueneman K,He J,Welner RS,Starczynowski DT,Bhatia R
13-5931-82 was used in Flow Cytometry to find that TNF-α-mediated alterations in CML BM stromal niches enhance support of LSC maintenance and growth via CXCL1-CXCR2 signaling and that CXCR2 inhibition effectively depletes CML LSCs.
Tue Jul 13 00:00:00 EDT 2021
Construction, characterization, and immunization of nanoparticles that display a diverse array of influenza HA trimers.
PloS one
Cohen AA,Yang Z,Gnanapragasam PNP,Ou S,Dam KA,Wang H,Bjorkman PJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Fri Oct 15 00:00:00 EDT 2021
Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist.
eLife
Glassman CR,Su L,Majri-Morrison SS,Winkelmann H,Mo F,Li P,Pérez-Cruz M,Ho PP,Koliesnik I,Nagy N,Hnizdilova T,Picton LK,Kovar M,Bollyky P,Steinman L,Meyer E,Piehler J,Leonard WJ,Garcia KC
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Tue May 18 00:00:00 EDT 2021
RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia.
Cell stem cell
Shen C,Sheng Y,Zhu AC,Robinson S,Jiang X,Dong L,Chen H,Su R,Yin Z,Li W,Deng X,Chen Y,Hu YC,Weng H,Huang H,Prince E,Cogle CR,Sun M,Zhang B,Chen CW,Marcucci G,He C,Qian Z,Chen J
13-5931-82 was used in Flow Cytometry to reveal crucial functions of ALKBH5 in leukemogenesis and LSC/LIC self-renewal/maintenance and highlight the therapeutic potential of targeting the ALKBH5/m6A axis.
Thu Jul 02 00:00:00 EDT 2020
BCG vaccination-induced emergency granulopoiesis provides rapid protection from neonatal sepsis.
Science translational medicine
Brook B,Harbeson DJ,Shannon CP,Cai B,He D,Ben-Othman R,Francis F,Huang J,Varankovich N,Liu A,Bao W,Bjerregaard-Andersen M,Schaltz-Buchholzer F,Sanca L,Golding CN,Larsen KL,Levy O,Kampmann B,Tan R,Charles A,Wynn JL,Shann F,Aaby P,Benn CS,Tebbutt SJ,Kollmann TR,Amenyogbe N
13-5931 was used in Flow cytometry/Cell sorting to show that BCG was also protective in a mouse model of neonatal polymicrobial sepsis, where it induced granulocyte colony-stimulating factor (G-CSF) within hours of administration.
Wed May 06 00:00:00 EDT 2020
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2020
Long-term ex vivo expansion of mouse hematopoietic stem cells.
Nature protocols
Wilkinson AC,Ishida R,Nakauchi H,Yamazaki S
13-5931 was used in Flow cytometry/Cell sorting to describe a simple platform for the expansion of functional mouse hematopoietic stem cells ex vivo for >1 month under fully defined albumin-free conditions.
Sat Feb 01 00:00:00 EST 2020
Notch2 complements Notch1 to mediate inductive signaling that initiates early T cell development.
The Journal of cell biology
Romero-Wolf M,Shin B,Zhou W,Koizumi M,Rothenberg EV,Hosokawa H
13-5931 was used in Flow cytometry/Cell sorting to define a distinct mechanism of Notch signal response that distinguishes the initial stages of murine T cell development.
Mon Oct 05 00:00:00 EDT 2020
In Situ Therapeutic Cancer Vaccination with an Oncolytic Virus Expressing Membrane-Tethered IL-2.
Molecular therapy oncolytics
Liu W,Dai E,Liu Z,Ma C,Guo ZS,Bartlett DL
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Fri Jun 26 00:00:00 EDT 2020
Deficiency of immunoglobulin E protects mice from experimental abdominal aortic aneurysms.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Li J,Deng Z,Zhang X,Liu F,Yang C,Shi GP
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2020
Flagellin-Stimulated Production of Interferon-β Promotes Anti-Flagellin IgG2c and IgA Responses.
Molecules and cells
Kang W,Park A,Huh JW,You G,Jung DJ,Song M,Lee HK,Kim YM
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Tue Mar 31 00:00:00 EDT 2020
Effects of Hypertonic Saline and Hydroxyethyl Starch on Myeloid-Derived Suppressor Cells in Hemorrhagic Shock Mice under Secondary Bacterial Attack.
BioMed research international
Jiang JK,Hong LJ,Lu YQ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Wed Dec 16 00:00:00 EST 2020
Long Non-Coding RNA Hotairm1 Promotes S100A9 Support of MDSC Expansion during Sepsis.
Journal of clinical & cellular immunology
Alkhateeb T,Bah I,Kumbhare A,Youssef D,Yao ZQ,McCall CE,Gazzar ME
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Sat Aug 13 00:00:00 EDT 2022
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Thu Sep 17 00:00:00 EDT 2020
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Thu Sep 17 00:00:00 EDT 2020
Hyaluronan Degradation by Cemip Regulates Host Defense against Staphylococcus aureus Skin Infection.
Cell reports
Dokoshi T,Zhang LJ,Li F,Nakatsuji T,Butcher A,Yoshida H,Shimoda M,Okada Y,Gallo RL
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Tue Jan 07 00:00:00 EST 2020
Renal proximal tubular NEMO plays a critical role in ischemic acute kidney injury.
JCI insight
Han SJ,Williams RM,Kim M,Heller DA,D'Agati V,Schmidt-Supprian M,Lee HT
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunohistochemistry
Thu Sep 17 00:00:00 EDT 2020
Loss of testosterone impairs anti-tumor neutrophil function.
Nature communications
Markman JL,Porritt RA,Wakita D,Lane ME,Martinon D,Noval Rivas M,Luu M,Posadas EM,Crother TR,Arditi M
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Tue Mar 31 00:00:00 EDT 2020
Bacterial and Fungal Toll-Like Receptor Activation Elicits Type I IFN Responses in Mast Cells.
Frontiers in immunology
Kornstädt L,Pierre S,Weigert A,Ebersberger S,Schäufele TJ,Kolbinger A,Schmid T,Cohnen J,Thomas D,Ferreirós N,Brüne B,Ebersberger I,Scholich K
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Mon Jun 21 00:00:00 EDT 2021
Sensing and signaling of immunogenic extracellular RNAs restrain group 2 innate lymphoid cell-driven acute lung inflammation and airway hyperresponsiveness.
PloS one
She L,Alanazi HH,Yan L,Brooks EG,Dube PH,Xiang Y,Zhang F,Sun Y,Liu Y,Zhang X,Li XD
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Thu Sep 24 00:00:00 EDT 2020
Prevention of acute kidney injury by low intensity pulsed ultrasound via anti-inflammation and anti-apoptosis.
Scientific reports
Chiang CK,Loh JZ,Yang TH,Huang KT,Wu CT,Guan SS,Liu SH,Hung KY
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunohistochemistry
Mon Aug 31 00:00:00 EDT 2020
Prevention of acute kidney injury by low intensity pulsed ultrasound via anti-inflammation and anti-apoptosis.
Scientific reports
Chiang CK,Loh JZ,Yang TH,Huang KT,Wu CT,Guan SS,Liu SH,Hung KY
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunohistochemistry
Mon Aug 31 00:00:00 EDT 2020
Protocol for Flow Cytometric Detection of Immune Cell Infiltration in the Epidermis and Dermis of a Psoriasis Mouse Model.
STAR protocols
Lou F,Sun Y,Wang H
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Fri Dec 18 00:00:00 EST 2020
Methylation of a CGATA element inhibits binding and regulation by GATA-1.
Nature communications
Yang L,Chen Z,Stout ES,Delerue F,Ittner LM,Wilkins MR,Quinlan KGR,Crossley M
13-5931 was used in Flow cytometry/Cell sorting to show that the erythroid transcription factor GATA-1 - that typically binds T/AGATA sites - can also recognise CGATA elements, but only if the CpG dinucleotide is unmethylated.
Fri May 22 00:00:00 EDT 2020
The endothelial protein C receptor plays an essential role in the maintenance of pregnancy.
Science advances
Castillo MM,Yang Q,Sigala AS,McKinney DT,Zhan M,Chen KL,Jarzembowski JA,Sood R
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunohistochemistry
Sun Nov 01 00:00:00 EDT 2020
Retroviral Overexpression of CXCR4 on Murine B-1a Cells and Adoptive Transfer for Targeted B-1a Cell Migration to the Bone Marrow and IgM Production.
Journal of visualized experiments : JoVE
Upadhye A,Marshall M,Garmey JC,Bender TP,McNamara C
13-5931 was used in Magnetic cell separation to describe a method to target B-1a cell migration to the bone marrow by retroviral-mediated overexpression of the C-X-C motif chemokine receptor 4 (CXCR4).
Sun May 31 00:00:00 EDT 2020
Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment.
eLife
Zhong L,Yao L,Tower RJ,Wei Y,Miao Z,Park J,Shrestha R,Wang L,Yu W,Holdreith N,Huang X,Zhang Y,Tong W,Gong Y,Ahn J,Susztak K,Dyment N,Li M,Long F,Chen C,Seale P,Qin L
13-5931 was used in Flow cytometry/Cell sorting to computationally define mesenchymal progenitors at different stages and delineate their bi-lineage differentiation paths in young, adult and aging mice.
Tue Apr 14 00:00:00 EDT 2020
Osterix-Cre marks distinct subsets of CD45- and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics.
eLife
Ricci B,Tycksen E,Celik H,Belle JI,Fontana F,Civitelli R,Faccio R
13-5931 was used in Flow cytometry/Cell sorting to find Osx transcript and Osx protein expression early during hematopoiesis, in subsets of hematopoietic stem cells and multipotent progenitor populations.
Wed Aug 05 00:00:00 EDT 2020
Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation.
Nature
Wilkinson AC,Ishida R,Kikuchi M,Sudo K,Morita M,Crisostomo RV,Yamamoto R,Loh KM,Nakamura Y,Watanabe M,Nakauchi H,Yamazaki S
13-5931 was used in Flow cytometry/Cell sorting to identify polyvinyl alcohol as a functionally superior replacement for serum albumin that is compatible with good manufacturing practice.
Mon Jul 01 00:00:00 EDT 2019
The cis-Regulatory Atlas of the Mouse Immune System.
Cell
Yoshida H,Lareau CA,Ramirez RN,Rose SA,Maier B,Wroblewska A,Desland F,Chudnovskiy A,Mortha A,Dominguez C,Tellier J,Kim E,Dwyer D,Shinton S,Nabekura T,Qi Y,Yu B,Robinette M,Kim KW,Wagers A,Rhoads A,Nutt SL,Brown BD,Mostafavi S,Buenrostro JD,Benoist C
13-5931-82 was used in Flow Cytometry to generate matched epigenome and transcriptome measurements in 86 primary cell types that span the mouse immune system and its differentiation cascade.
Thu Feb 07 00:00:00 EST 2019
Metabolic Imaging Reveals a Unique Preference of Symmetric Cell Division and Homing of Leukemia-Initiating Cells in an Endosteal Niche.
Cell metabolism
Hao X,Gu H,Chen C,Huang D,Zhao Y,Xie L,Zou Y,Shu HS,Zhang Y,He X,Lai X,Zhang X,Zhou BO,Zhang CC,Chen GQ,Yu Z,Yang Y,Zheng J
13-5931 was used in Flow cytometry/Cell sorting to provide a unique angle for the study of metabolisms in stem cells, and may lead to development of novel strategies for cancer treatment.
Tue Apr 02 00:00:00 EDT 2019
Mesenchymal Niche-Specific Expression of Cxcl12 Controls Quiescence of Treatment-Resistant Leukemia Stem Cells.
Cell stem cell
Agarwal P,Isringhausen S,Li H,Paterson AJ,He J,Gomariz Á,Nagasawa T,Nombela-Arrieta C,Bhatia R
13-5931-82 was used in Flow Cytometry to highlight a critical role of niche-specific effects of Cxcl12 expression in maintaining quiescence of TKI-resistant LSC populations.
Thu May 02 00:00:00 EDT 2019
Neutrophils contribute to spontaneous resolution of liver inflammation and fibrosis via microRNA-223.
The Journal of clinical investigation
Calvente CJ,Tameda M,Johnson CD,Del Pilar H,Lin YC,Adronikou N,De Mollerat Du Jeu X,Llorente C,Boyer J,Feldstein AE
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Thu Jul 11 00:00:00 EDT 2019
SIRT1 regulates metabolism and leukemogenic potential in CML stem cells.
The Journal of clinical investigation
Abraham A,Qiu S,Chacko BK,Li H,Paterson A,He J,Agarwal P,Shah M,Welner R,Darley-Usmar VM,Bhatia R
13-5931 was used in Flow cytometry/Cell sorting to demonstrate an important role for SIRT1 in leukemia development.
Mon Jun 10 00:00:00 EDT 2019
S100A9 maintains myeloid-derived suppressor cells in chronic sepsis by inducing miR-21 and miR-181b.
Molecular immunology
Alkhateeb T,Kumbhare A,Bah I,Youssef D,Yao ZQ,McCall CE,El Gazzar M
13-5931-82 was used in Flow Cytometry to show that S100A9 induces miR-21 and miR-181b during the late sepsis phase.
Thu Aug 01 00:00:00 EDT 2019
The role of platelets in mediating a response to human influenza infection.
Nature communications
Koupenova M,Corkrey HA,Vitseva O,Manni G,Pang CJ,Clancy L,Yao C,Rade J,Levy D,Wang JP,Finberg RW,Kurt-Jones EA,Freedman JE
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunocytochemistry
Tue Apr 16 00:00:00 EDT 2019
Neutrophil extracellular traps induced by VP1 contribute to pulmonary edema during EV71 infection.
Cell death discovery
Wang N,Yang X,Sun J,Sun Z,Ma Q,Wang Z,Chen Z,Wang Z,Hu F,Wang H,Zhou L,Zhang M,Xu J
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Wed Sep 30 00:00:00 EDT 2020
Methods for Evaluating the Role of c-Fos and Dusp1 in Oncogene Dependence.
Journal of visualized experiments : JoVE
Kesarwani M,Kincaid Z,Azam M
13-5931 was used in Flow cytometry/Cell sorting to provide methods for target validation using in vitro and in vivo mouse models.
Mon Jan 07 00:00:00 EST 2019
Nidogen-1 Contributes to the Interaction Network Involved in Pro-B Cell Retention in the Peri-sinusoidal Hematopoietic Stem Cell Niche.
Cell reports
Balzano M,De Grandis M,Vu Manh TP,Chasson L,Bardin F,Farina A,Sergé A,Bidaut G,Charbord P,Hérault L,Bailly AL,Cartier-Michaud A,Boned A,Dalod M,Duprez E,Genever P,Coles M,Bajenoff M,Xerri L,Aurrand-Lions M,Schiff C,Mancini SJC
13-5931 was used in Flow cytometry/Cell sorting to study pro-B cells in their support of stroll cells and their interaction network allowing their retention.
Tue Mar 19 00:00:00 EDT 2019
N-Cadherin-Expressing Bone and Marrow Stromal Progenitor Cells Maintain Reserve Hematopoietic Stem Cells.
Cell reports
Zhao M,Tao F,Venkatraman A,Li Z,Smith SE,Unruh J,Chen S,Ward C,Qian P,Perry JM,Marshall H,Wang J,He XC,Li L
13-5931 was used in Flow cytometry/Cell sorting to report that N-cad+ cells were functional bone and marrow stromal progenitor cells, giving rise to osteoblasts, adipocytes, and chondrocytes both in vitro and in vivo.
Tue Jan 15 00:00:00 EST 2019
Antitumor immunity augments the therapeutic effects of p53 activation on acute myeloid leukemia.
Nature communications
Hayashi Y,Goyama S,Liu X,Tamura M,Asada S,Tanaka Y,Fukuyama T,Wunderlich M,O'Brien E,Mizukawa B,Yamazaki S,Matsumoto A,Yamasaki S,Shibata T,Matsuda K,Sashida G,Takizawa H,Kitamura T
13-5931-82 was used in Flow Cytometry to show that an orally active inhibitor of p53-MDM2 interaction, DS-5272, causes dramatic tumour regressions of MLL-AF9-driven acute myeloid leukemia in vivo with a tolerable toxicity.
Fri Oct 25 00:00:00 EDT 2019
Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia.
Nature medicine
Zhang B,Nguyen LXT,Li L,Zhao D,Kumar B,Wu H,Lin A,Pellicano F,Hopcroft L,Su YL,Copland M,Holyoake TL,Kuo CJ,Bhatia R,Snyder DS,Ali H,Stein AS,Brewer C,Wang H,McDonald T,Swiderski P,Troadec E,Chen CC,Dorrance A,Pullarkat V,Yuan YC,Perrotti D,Carlesso N,Forman SJ,Kortylewski M,Kuo YH,Marcucci G
13-5931 was used in Flow cytometry/Cell sorting to demonstrate how bone marrow endothelial cells supply miR-126 to leukemia stem cells in chronic myelogenous leukemia which modulates their quiescence and self-renewal.
Tue May 01 00:00:00 EDT 2018
E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor.
Immunity
Li Q,Li D,Zhang X,Wan Q,Zhang W,Zheng M,Zou L,Elly C,Lee JH,Liu YC
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Tue Feb 20 00:00:00 EST 2018
Interleukin-17-Producing γδ T Cells Originate from SOX13+ Progenitors that Are Independent of γδTCR Signaling.
Immunity
Spidale NA,Sylvia K,Narayan K,Miu B,Frascoli M,Melichar HJ,Zhihao W,Kisielow J,Palin A,Serwold T,Love P,Kobayashi M,Yoshimoto M,Jain N,Kang J
13-5931-82 was used in Flow Cytometry to generate reporter mice for the Tγδ17 lineage-defining transcription factor SOX13 and identify fetal-origin, intrathymic Sox13+ progenitors.
Tue Nov 20 00:00:00 EST 2018
Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment.
Cell stem cell
Yamamoto R,Wilkinson AC,Ooehara J,Lan X,Lai CY,Nakauchi Y,Pritchard JK,Nakauchi H
13-5931 was used in Flow cytometry/Cell sorting to determine the age-related functional changes to the haematopoietic stem cell compartment.
Thu Apr 05 00:00:00 EDT 2018
IL1RAP potentiates multiple oncogenic signaling pathways in AML.
The Journal of experimental medicine
Mitchell K,Barreyro L,Todorova TI,Taylor SJ,Antony-Debré I,Narayanagari SR,Carvajal LA,Leite J,Piperdi Z,Pendurti G,Mantzaris I,Paietta E,Verma A,Gritsman K,Steidl U
13-5931 was used in Flow cytometry/Cell sorting to show that targeting of interleukin-1 receptor accessory protein via RNA interference, genetic deletion, or antibodies inhibits acute myeloid leukaemia pathogenesis in vitro and in vivo.
Mon Jun 04 00:00:00 EDT 2018
Proapoptotic BIM Impacts B Lymphoid Homeostasis by Limiting the Survival of Mature B Cells in a Cell-Autonomous Manner.
Frontiers in immunology
Liu R,King A,Bouillet P,Tarlinton DM,Strasser A,Heierhorst J
13-5931 was used in Flow cytometry/Cell sorting to indicate that BIM regulates B cell homeostasis predominantly by limiting the life span of non-activated mature B cells.
Wed May 01 00:00:00 EDT 2019
Loss of DEK induces radioresistance of murine restricted hematopoietic progenitors.
Experimental hematology
Serrano-Lopez J,Nattamai K,Pease NA,Shephard MS,Wellendorf AM,Sertorio M,Smith EA,Geiger H,Wells SI,Cancelas JA,Privette Vinnedge LM
13-5931 was used in Flow cytometry/Cell sorting to investigate the role of DEK in normal hematopoiesis and response to DNA damaging agents in vivo.
Thu Mar 01 00:00:00 EST 2018
Investigation of tumor-tumor interactions in a double human cervical carcinoma xenograft model in nude mice.
Oncotarget
Mertens B,Cristina de Araujo Nogueira T,Topalis D,Stranska R,Snoeck R,Andrei G
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Tue Apr 24 00:00:00 EDT 2018
Analysis of leukocyte transepithelial migration using an in vivo murine colonic loop model.
JCI insight
Flemming S,Luissint AC,Nusrat A,Parkos CA
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunofluorescence
Thu Oct 18 00:00:00 EDT 2018
Antiviral effects of ferric ammonium citrate.
Cell discovery
Wang H,Li Z,Niu J,Xu Y,Ma L,Lu A,Wang X,Qian Z,Huang Z,Jin X,Leng Q,Wang J,Zhong J,Sun B,Meng G
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2020
Induction of neutrophil apoptosis by a Bcl-2 inhibitor reduces particulate matter-induced lung inflammation.
Aging
Geng X,Wang X,Luo M,Xing M,Wu Y,Li W,Chen Z,Shen H,Ying S
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Tue Jun 26 00:00:00 EDT 2018
Microbiota Reconstitution Does Not Cause Bone Loss in Germ-Free Mice.
mSphere
Quach D,Collins F,Parameswaran N,McCabe L,Britton RA
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress.
Cell stem cell
Tadokoro Y,Hoshii T,Yamazaki S,Eto K,Ema H,Kobayashi M,Ueno M,Ohta K,Arai Y,Hara E,Harada K,Oshima M,Oshima H,Arai F,Yoshimura A,Nakauchi H,Hirao A
13-5931-82 was used in Flow Cytometry to demonstrate the involvement of diet-induced stress on hematopoietic stem cell self-renewal.
Thu May 03 00:00:00 EDT 2018
Hematopoietic stem cells can differentiate into restricted myeloid progenitors before cell division in mice.
Nature communications
Grinenko T,Eugster A,Thielecke L,Ramasz B,Krüger A,Dietz S,Glauche I,Gerbaulet A,von Bonin M,Basak O,Clevers H,Chavakis T,Wielockx B
13-5931-82 was used in Magnetic cell separation to study the mechanisms that control fate decision in adult haematopoietic stem cells.s.
Tue May 15 00:00:00 EDT 2018
A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment.
eLife
Ng KK,Yui MA,Mehta A,Siu S,Irwin B,Pease S,Hirose S,Elowitz MB,Rothenberg EV,Kueh HY
13-5931 was used in Flow cytometry/Cell sorting to study the activation of Bcl11b, which controls T-cell fate commitment.
Tue Nov 20 00:00:00 EST 2018
The orphan nuclear receptor EAR-2 (NR2F6) inhibits hematopoietic cell differentiation and induces myeloid dysplasia in vivo.
Biomarker research
Ichim CV,Dervovic DD,Chan LSA,Robertson CJ,Chesney A,Reis MD,Wells RA
Wed Mar 30 00:00:00 EDT 2022
Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias.
Nature communications
Chaudhury S,O'Connor C,Cañete A,Bittencourt-Silvestre J,Sarrou E,Prendergast Á,Choi J,Johnston P,Wells CA,Gibson B,Keeshan K
13-5931 was used in Flow cytometry/Cell sorting to study paediatric acute myeloid leukaemia biology, and provide murine models that offer the potential for developing paediatric specific therapeutic strategies.
Tue Dec 11 00:00:00 EST 2018
TGF-β1 Negatively Regulates the Number and Function of Hematopoietic Stem Cells.
Stem cell reports
Wang X,Dong F,Zhang S,Yang W,Yu W,Wang Z,Zhang S,Wang J,Ma S,Wu P,Gao Y,Dong J,Tang F,Cheng T,Ema H
13-5931 was used in Flow cytometry/Cell sorting to examine the effect of transforming growth factor Β1 on haematopoietic stem cell function.
Tue Jul 10 00:00:00 EDT 2018
Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate.
Cell
Isoda T,Moore AJ,He Z,Chandra V,Aida M,Denholtz M,Piet van Hamburg J,Fisch KM,Chang AN,Fahl SP,Wiest DL,Murre C
13-5931-82 was used in Flow Cytometry to study the repositioning of the Bcl11b enhancer to dictate the fate of developing T cells.
Thu Sep 21 00:00:00 EDT 2017
Vitamin A-Retinoic Acid Signaling Regulates Hematopoietic Stem Cell Dormancy.
Cell
Cabezas-Wallscheid N,Buettner F,Sommerkamp P,Klimmeck D,Ladel L,Thalheimer FB,Pastor-Flores D,Roma LP,Renders S,Zeisberger P,Przybylla A,Schönberger K,Scognamiglio R,Altamura S,Florian CM,Fawaz M,Vonficht D,Tesio M,Collier P,Pavlinic D,Geiger H,Schroeder T,Benes V,Dick TP,Rieger MA,Stegle O,Trumpp A
13-5931 was used in Flow cytometry/Cell sorting to highlight the impact of dietary vitamin A on the regulation of cell-cycle-mediated stem cell plasticity.
Thu May 18 00:00:00 EDT 2017
AMP-Activated Protein Kinase α2 in Neutrophils Regulates Vascular Repair via Hypoxia-Inducible Factor-1α and a Network of Proteins Affecting Metabolism and Apoptosis.
Circulation research
Abdel Malik R,Zippel N,Frömel T,Heidler J,Zukunft S,Walzog B,Ansari N,Pampaloni F,Wingert S,Rieger MA,Wittig I,Fisslthaler B,Fleming I
13-5931 was used in Flow cytometry/Cell sorting to elucidate the role of the AMPKa2 catalytic subunit in vascular repair following ischemia.
Fri Jan 06 00:00:00 EST 2017
Brd4 modulates the innate immune response through Mnk2-eIF4E pathway-dependent translational control of IκBα.
Proceedings of the National Academy of Sciences of the United States of America
Bao Y,Wu X,Chen J,Hu X,Zeng F,Cheng J,Jin H,Lin X,Chen LF
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Tue May 16 00:00:00 EDT 2017
Pre/pro-B cells generate macrophage populations during homeostasis and inflammation.
Proceedings of the National Academy of Sciences of the United States of America
Audzevich T,Bashford-Rogers R,Mabbott NA,Frampton D,Freeman TC,Potocnik A,Kellam P,Gilroy DW
13-5931 was used in Flow cytometry/Cell sorting to study the developmental plasticity of immature B cells and their role as the source of tissue resident macrophages.
Tue May 16 00:00:00 EDT 2017
Stat3 and C/EBPβ synergize to induce miR-21 and miR-181b expression during sepsis.
Immunology and cell biology
McClure C,McPeak MB,Youssef D,Yao ZQ,McCall CE,El Gazzar M
13-5931 was used in Flow cytometry/Cell sorting to examine how sepsis regulates microRNA-21 and miR-181b transcription.
Sun Jan 01 00:00:00 EST 2017
Cardiac inflammation in genetic dilated cardiomyopathy caused by MYBPC3 mutation.
Journal of molecular and cellular cardiology
Lynch TL,Ismahil MA,Jegga AG,Zilliox MJ,Troidl C,Prabhu SD,Sadayappan S
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
Cardiac inflammation in genetic dilated cardiomyopathy caused by MYBPC3 mutation.
Journal of molecular and cellular cardiology
Lynch TL,Ismahil MA,Jegga AG,Zilliox MJ,Troidl C,Prabhu SD,Sadayappan S
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
Silybin attenuates LPS-induced lung injury in mice by inhibiting NF-κB signaling and NLRP3 activation.
International journal of molecular medicine
Zhang B,Wang B,Cao S,Wang Y,Wu D
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2017
ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis.
RNA biology
Ben-Shoshan SO,Kagan P,Sultan M,Barabash Z,Dor C,Jacob-Hirsch J,Harmelin A,Pappo O,Marcu-Malina V,Ben-Ari Z,Amariglio N,Rechavi G,Goldstein I,Safran M
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Thu May 04 00:00:00 EDT 2017
Expression of C/EBPβ in myeloid progenitors during sepsis promotes immunosuppression.
Molecular immunology
Dai J,Kumbhare A,Youssef D,Yao ZQ,McCall CE,El Gazzar M
13-5931 was used in Flow cytometry/Cell sorting to assess how the expression of C/EBPΒ in myeloid progenitors during sepsis promotes immunosuppression.
Wed Nov 01 00:00:00 EDT 2017
Myeloid Cell-Specific Knockout of NFI-A Improves Sepsis Survival.
Infection and immunity
McPeak MB,Youssef D,Williams DA,Pritchett C,Yao ZQ,McCall CE,El Gazzar M
13-5931 was used in Flow cytometry/Cell sorting to show sepsis survival outcome can be improved by knock-out of myeloid differentiation-related transcription factor nuclear factor I-A which controls myeloid progenitor-derived suppressor cell expansion during sepsis.
Sat Apr 01 00:00:00 EDT 2017
MiR-125a Is a critical modulator for neutrophil development.
PLoS genetics
Qin Y,Wu L,Ouyang Y,Zhou P,Zhou H,Wang Y,Ma J,Zhang J,Chen Y,Qian J,Tang Y,Shen N
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Sun Oct 01 00:00:00 EDT 2017
Gastric TFF1 Expression from Acute to Chronic Helicobacter Infection.
Frontiers in cellular and infection microbiology
Esposito R,Morello S,Vllahu M,Eletto D,Porta A,Tosco A
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunohistochemistry
Mon Jul 09 00:00:00 EDT 2018
Recipient bone marrow assimilates the myeloid/lymphoid reconstitution of distinct fetal hematopoietic stem cells.
Oncotarget
Guo XL,Chu L,Ke F,Mu LL,Li Z,Cai JJ,Li HF,Hong DL
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Tue Dec 12 00:00:00 EST 2017
BOT-4-one attenuates NLRP3 inflammasome activation: NLRP3 alkylation leading to the regulation of its ATPase activity and ubiquitination.
Scientific reports
Shim DW,Shin WY,Yu SH,Kim BH,Ye SK,Koppula S,Won HS,Kang TB,Lee KH
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Wed Nov 08 00:00:00 EST 2017
Tumor-Derived Exosomes Induce the Formation of Neutrophil Extracellular Traps: Implications For The Establishment of Cancer-Associated Thrombosis.
Scientific reports
Leal AC,Mizurini DM,Gomes T,Rochael NC,Saraiva EM,Dias MS,Werneck CC,Sielski MS,Vicente CP,Monteiro RQ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunohistochemistry
Tue Jul 25 00:00:00 EDT 2017
One Year Follow-Up Risk Assessment in SKH-1 Mice and Wounds Treated with an Argon Plasma Jet.
International journal of molecular sciences
Schmidt A,Woedtke TV,Stenzel J,Lindner T,Polei S,Vollmar B,Bekeschus S
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunofluorescence
Wed Apr 19 00:00:00 EDT 2017
In vitro Detection of Neutrophil Traps and Post-attack Cell Wall Changes in Candida Hyphae.
Bio-protocol
Hopke A,Wheeler RT
13-5931-82 was used in Magnetic cell separation to describe how to visualize neutrophil extracellular traps and fungal cell wall changes ine coculturing mouse neutrophils with Candida albicans fungal hyphae.
Wed Apr 05 00:00:00 EDT 2017
Understanding Hematopoietic Stem Cell Development through Functional Correlation of Their Proliferative Status with the Intra-aortic Cluster Architecture.
Stem cell reports
Batsivari A,Rybtsov S,Souilhol C,Binagui-Casas A,Hills D,Zhao S,Travers P,Medvinsky A
13-5931 was used in Flow cytometry/Cell sorting to observe time-specific changes in intra-aortic hematopoietic clusters corresponding to HSC maturation stages.
Tue Jun 06 00:00:00 EDT 2017
Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome.
Nature communications
Shirai CL,White BS,Tripathi M,Tapia R,Ley JN,Ndonwi M,Kim S,Shao J,Carver A,Saez B,Fulton RS,Fronick C,O'Laughlin M,Lagisetti C,Webb TR,Graubert TA,Walter MJ
13-5931 was used in Flow cytometry/Cell sorting to suggest a potential for treating haematological cancers harbouring U2AF1 mutations with pre-mRNA splicing modulators like sudemycins.
Mon Jan 09 00:00:00 EST 2017
Combinatorial hydrogel library enables identification of materials that mitigate the foreign body response in primates.
Nature biotechnology
Vegas AJ,Veiseh O,Doloff JC,Ma M,Tam HH,Bratlie K,Li J,Bader AR,Langan E,Olejnik K,Fenton P,Kang JW,Hollister-Locke J,Bochenek MA,Chiu A,Siebert S,Tang K,Jhunjhunwala S,Aresta-Dasilva S,Dholakia N,Thakrar R,Vietti T,Chen M,Cohen J,Siniakowicz K,Qi M,McGarrigle J,Graham AC,Lyle S,Harlan DM,Greiner DL,Oberholzer J,Weir GC,Langer R,Anderson DG
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.
Cell
Damgaard RB,Walker JA,Marco-Casanova P,Morgan NV,Titheradge HL,Elliott PR,McHale D,Maher ER,McKenzie ANJ,Komander D
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Thu Aug 25 00:00:00 EDT 2016
Hematopoietic Stem Cells Count and Remember Self-Renewal Divisions.
Cell
Bernitz JM,Kim HS,MacArthur B,Sieburg H,Moore K
13-5931 was used in Flow cytometry/Cell sorting to suggest that HSCs accumulate discrete memory stages over their divisional history and identify cellular memory in HSC aging.
Thu Nov 17 00:00:00 EST 2016
Acidic chitinase primes the protective immune response to gastrointestinal nematodes.
Nature immunology
Vannella KM,Ramalingam TR,Hart KM,de Queiroz Prado R,Sciurba J,Barron L,Borthwick LA,Smith AD,Mentink-Kane M,White S,Thompson RW,Cheever AW,Bock K,Moore I,Fitz LJ,Urban JF,Wynn TA
13-5931 was used in Flow cytometry/Cell sorting to use AMCase-deficient mice as a means to dissect the role of the enzyme in several models of helminth infection and type 2 cytokine-driven airway inflammation.
Sun May 01 00:00:00 EDT 2016
Lymphatic vessels regulate immune microenvironments in human and murine melanoma.
The Journal of clinical investigation
Lund AW,Wagner M,Fankhauser M,Steinskog ES,Broggi MA,Spranger S,Gajewski TF,Alitalo K,Eikesdal HP,Wiig H,Swartz MA
13-5931 was used in Flow cytometry/Cell sorting to suggest that the establishment of tumour-associated inflammation and immunity critically depends on lymphatic vessel remodelling and drainage.
Thu Sep 01 00:00:00 EDT 2016
PML-RARA requires DNA methyltransferase 3A to initiate acute promyelocytic leukemia.
The Journal of clinical investigation
Cole CB,Verdoni AM,Ketkar S,Leight ER,Russler-Germain DA,Lamprecht TL,Demeter RT,Magrini V,Ley TJ
13-5931 was used in Flow cytometry/Cell sorting to suggest that PML-RARA requires DNMT3A to initiate acute promyelocytic leukemia in mice.
Fri Jan 01 00:00:00 EST 2016
IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization.
The Journal of experimental medicine
Yoon J,Leyva-Castillo JM,Wang G,Galand C,Oyoshi MK,Kumar L,Hoff S,He R,Chervonsky A,Oppenheim JJ,Kuchroo VK,van den Brink MR,Malefyt Rde W,Tessier PA,Fuhlbrigge R,Rosenstiel P,Terhorst C,Murphy G,Geha RS
13-5931 was used in Flow cytometry/Cell sorting to elucidate the mechanisms behind DC-derived IL-23 in a model of skin inflammation.
Mon Sep 19 00:00:00 EDT 2016
CD8+ T cells drive autoimmune hematopoietic stem cell dysfunction and bone marrow failure.
Journal of autoimmunity
Gravano DM,Al-Kuhlani M,Davini D,Sanders PD,Manilay JO,Hoyer KK
13-5931 was used in Flow cytometry/Cell sorting to investigate whether CD8+ T cells play a non-redundant role in driving bone marrow failure.
Thu Dec 01 00:00:00 EST 2016
Multiple myeloma exosomes establish a favourable bone marrow microenvironment with enhanced angiogenesis and immunosuppression.
The Journal of pathology
Wang J,De Veirman K,Faict S,Frassanito MA,Ribatti D,Vacca A,Menu E
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Wed Jun 01 00:00:00 EDT 2016
Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth.
Stem cells translational medicine
Zheng H,Zou W,Shen J,Xu L,Wang S,Fu YX,Fan W
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses.
Immunology
Xu Y,Liu Y,Yang C,Kang L,Wang M,Hu J,He H,Song W,Tang H
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Sat Oct 01 00:00:00 EDT 2016
NFI-A disrupts myeloid cell differentiation and maturation in septic mice.
Journal of leukocyte biology
McClure C,Ali E,Youssef D,Yao ZQ,McCall CE,El Gazzar M
Fri Jan 01 00:00:00 EST 2016
Identification of Immune Effectors Essential to the Control of Primary and Secondary Intranasal Infection with Brucella melitensis in Mice.
Journal of immunology (Baltimore, Md. : 1950)
Hanot Mambres D,Machelart A,Potemberg G,De Trez C,Ryffel B,Letesson JJ,Muraille E
13-5931 was used in Flow cytometry/Cell sorting to demonstrate that the nature of the protective memory response depends closely on the route of infection and highlights the role of IFN-γ-and IL-17RA-mediated responses in the control of mucosal infection by Brucella.
Sun May 01 00:00:00 EDT 2016
The miR-17∼92 cluster contributes to MLL leukemia through the repression of MEIS1 competitor PKNOX1.
Leukemia research
Mian YA,Zeleznik-Le NJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Fri Jul 01 00:00:00 EDT 2016
Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency.
Stem cell reports
Mucci A,Kunkiel J,Suzuki T,Brennig S,Glage S,Kühnel MP,Ackermann M,Happle C,Kuhn A,Schambach A,Trapnell BC,Hansen G,Moritz T,Lachmann N
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Tue Aug 09 00:00:00 EDT 2016
Activated c-Kit receptor in the heart promotes cardiac repair and regeneration after injury.
Cell death & disease
Di Siena S,Gimmelli R,Nori SL,Barbagallo F,Campolo F,Dolci S,Rossi P,Venneri MA,Giannetta E,Gianfrilli D,Feigenbaum L,Lenzi A,Naro F,Cianflone E,Mancuso T,Torella D,Isidori AM,Pellegrini M
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunofluorescence
Thu Jul 28 00:00:00 EDT 2016
Activated c-Kit receptor in the heart promotes cardiac repair and regeneration after injury.
Cell death & disease
Di Siena S,Gimmelli R,Nori SL,Barbagallo F,Campolo F,Dolci S,Rossi P,Venneri MA,Giannetta E,Gianfrilli D,Feigenbaum L,Lenzi A,Naro F,Cianflone E,Mancuso T,Torella D,Isidori AM,Pellegrini M
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunofluorescence
Thu Jul 28 00:00:00 EDT 2016
Influenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice.
BMC genomics
Leist SR,Pilzner C,van den Brand JM,Dengler L,Geffers R,Kuiken T,Balling R,Kollmus H,Schughart K
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Sat Feb 27 00:00:00 EST 2016
Stroke Damage Is Exacerbated by Nano-Size Particulate Matter in a Mouse Model.
PloS one
Liu Q,Babadjouni R,Radwanski R,Cheng H,Patel A,Hodis DM,He S,Baumbacher P,Russin JJ,Morgan TE,Sioutas C,Finch CE,Mack WJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunofluorescence
Tue Aug 23 00:00:00 EDT 2016
C/EBP homologous protein (CHOP) deficiency ameliorates renal fibrosis in unilateral ureteral obstructive kidney disease.
Oncotarget
Liu SH,Wu CT,Huang KH,Wang CC,Guan SS,Chen LP,Chiang CK
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunohistochemistry
Tue Apr 19 00:00:00 EDT 2016
Enhancement of Oral Tolerance Induction in DO11.10 Mice by Lactobacillus gasseri OLL2809 via Increase of Effector Regulatory T Cells.
PloS one
Aoki-Yoshida A,Yamada K,Hachimura S,Sashihara T,Ikegami S,Shimizu M,Totsuka M
13-5931 was used in Flow cytometry/Cell sorting to evaluate how oral administration of the probiotic LG2809 influences immune cells in an induced oral tolerance mouse model.
Wed Aug 02 00:00:00 EDT 2017
SWEF Proteins Distinctly Control Maintenance and Differentiation of Hematopoietic Stem Cells.
PloS one
Ripich T,Chacón-Martínez CA,Fischer L,Pernis A,Kiessling N,Garbe AI,Jessberger R
13-5931 was used in Flow cytometry/Cell sorting to investigate the role of SWAP-70 and DEF6 in hematopoietic stem and precursor cells.
Mon Jul 31 00:00:00 EDT 2017
Affinity and dose of TCR engagement yield proportional enhancer and gene activity in CD4+ T cells.
eLife
Allison KA,Sajti E,Collier JG,Gosselin D,Troutman TD,Stone EL,Hedrick SM,Glass CK
13-5931 was used in Magnetic cell separation to investigate relationship between the strength of antigenic stimulation and the response of mouse CD4+ T cells.
Mon Jul 04 00:00:00 EDT 2016
p38 MAPK Inhibitor Insufficiently Attenuates HSC Senescence Administered Long-Term after 6 Gy Total Body Irradiation in Mice.
International journal of molecular sciences
Lu L,Wang YY,Zhang JL,Li DG,Meng AM
13-5931 was used in Flow cytometry/Cell sorting to investigate the effects of SB203580 on long-term TBI-induced myelosuppression.
Wed Jun 08 00:00:00 EDT 2016
T cells mediate autoantibody-induced cutaneous inflammation and blistering in epidermolysis bullosa acquisita.
Scientific reports
Bieber K,Witte M,Sun S,Hundt JE,Kalies K,Dräger S,Kasprick A,Twelkmeyer T,Manz RA,König P,Köhl J,Zillikens D,Ludwig RJ
13-5931 was used in Immunofluorescence in immunohistochemistry on frozen tissues to investigate the contribution of T cells to the effector phase of antibody-mediated autoimmune dermatoses.
Mon Dec 05 00:00:00 EST 2016
Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies.
Blood
Matthews GM,Mehdipour P,Cluse LA,Falkenberg KJ,Wang E,Roth M,Santoro F,Vidacs E,Stanley K,House CM,Rusche JR,Vakoc CR,Zuber J,Minucci S,Johnstone RW
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Thu Nov 19 00:00:00 EST 2015
Imaging Macrophage and Hematopoietic Progenitor Proliferation in Atherosclerosis.
Circulation research
Ye YX,Calcagno C,Binderup T,Courties G,Keliher EJ,Wojtkiewicz GR,Iwamoto Y,Tang J,Pérez-Medina C,Mani V,Ishino S,Johnbeck CB,Knigge U,Fayad ZA,Libby P,Weissleder R,Tawakol A,Dubey S,Belanger AP,Di Carli MF,Swirski FK,Kjaer A,Mulder WJ,Nahrendorf M
13-5931 was used in Flow cytometry/Cell sorting to perform (18)F-FLT positron emission tomography-computed tomography was performed in mice, rabbits, and humans with atherosclerosis.
Fri Oct 23 00:00:00 EDT 2015
Distinct germinal center selection at local sites shapes memory B cell response to viral escape.
The Journal of experimental medicine
Adachi Y,Onodera T,Yamada Y,Daio R,Tsuiji M,Inoue T,Kobayashi K,Kurosaki T,Ato M,Takahashi Y
13-5931 was used in Flow cytometry/Cell sorting to investigate the cellular events dictating the cross-reactive memory B cell responses, showing that distinct germinal center selection at local sites shapes response to viral escape.
Mon Sep 21 00:00:00 EDT 2015
Distinct germinal center selection at local sites shapes memory B cell response to viral escape.
The Journal of experimental medicine
Adachi Y,Onodera T,Yamada Y,Daio R,Tsuiji M,Inoue T,Kobayashi K,Kurosaki T,Ato M,Takahashi Y
13-5931 was used in Flow cytometry/Cell sorting to investigate the cellular events dictating the cross-reactive memory B cell responses, showing that distinct germinal center selection at local sites shapes response to viral escape.
Mon Sep 21 00:00:00 EDT 2015
BAFF activation of the ERK5 MAP kinase pathway regulates B cell survival.
The Journal of experimental medicine
Jacque E,Schweighoffer E,Tybulewicz VL,Ley SC
13-5931 was used in Flow cytometry/Cell sorting to reveal a potentially critical role for the MEK5-ERK5 MAP kinase signalling pathway in BAFF-induced mature B cell survival and homeostatic maintenance of B2 cell numbers.
Mon Jun 01 00:00:00 EDT 2015
Premature thymic involution is independent of structural plasticity of the thymic stroma.
European journal of immunology
Franckaert D,Schlenner SM,Heirman N,Gill J,Skogberg G,Ekwall O,Put K,Linterman MA,Dooley J,Liston A
13-5931 was used in Flow cytometry/Cell sorting to investigate thymic involution in FVB/N mice, showing that disruption of the epithelial-endothelial relationship and a progressive loss of pro-T cells precedes involution, and loss of pro-T cells is sufficient to drive premature involution, suggesting that pro-T cells are the main driver of involution.
Fri May 01 00:00:00 EDT 2015
The receptor for advanced glycation end products (RAGE) enhances autophagy and neutrophil extracellular traps in pancreatic cancer.
Cancer gene therapy
Boone BA,Orlichenko L,Schapiro NE,Loughran P,Gianfrate GC,Ellis JT,Singhi AD,Kang R,Tang D,Lotze MT,Zeh HJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunofluorescence
Mon Jun 01 00:00:00 EDT 2015
The receptor for advanced glycation end products (RAGE) enhances autophagy and neutrophil extracellular traps in pancreatic cancer.
Cancer gene therapy
Boone BA,Orlichenko L,Schapiro NE,Loughran P,Gianfrate GC,Ellis JT,Singhi AD,Kang R,Tang D,Lotze MT,Zeh HJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunofluorescence
Mon Jun 01 00:00:00 EDT 2015
Frizzled-6 Regulates Hematopoietic Stem/Progenitor Cell Survival and Self-Renewal.
Journal of immunology (Baltimore, Md. : 1950)
Abidin BM,Owusu Kwarteng E,Heinonen KM
13-5931 was used in Flow cytometry/Cell sorting to reveal that Fzd6 has an essential role in HSPC maintenance and survival.
Tue Sep 01 00:00:00 EDT 2015
A far-red fluorescent probe for flow cytometry and image-based functional studies of xenobiotic sequestering macrophages.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Keswani RK,Yoon GS,Sud S,Stringer KA,Rosania GR
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Local delivery of VEGF and SDF enhances endothelial progenitor cell recruitment and resultant recovery from ischemia.
Tissue engineering. Part A
Anderson EM,Kwee BJ,Lewin SA,Raimondo T,Mehta M,Mooney DJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
Reducing progression of experimental lupus nephritis via inhibition of the B7/CD28 signaling pathway.
Molecular medicine reports
Huang L,Kong Y,Wang J,Sun J,Shi Q,Qiu YH
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
The bone marrow microenvironment enhances multiple myeloma progression by exosome-mediated activation of myeloid-derived suppressor cells.
Oncotarget
Wang J,De Veirman K,De Beule N,Maes K,De Bruyne E,Van Valckenborgh E,Vanderkerken K,Menu E
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Tue Dec 22 00:00:00 EST 2015
The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia.
Nature communications
Koh HS,Chang CY,Jeon SB,Yoon HJ,Ahn YH,Kim HS,Kim IH,Jeon SH,Johnson RS,Park EJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunofluorescence
Fri Mar 20 00:00:00 EDT 2015
Targeted Gene Correction in Osteopetrotic-Induced Pluripotent Stem Cells for the Generation of Functional Osteoclasts.
Stem cell reports
Neri T,Muggeo S,Paulis M,Caldana ME,Crisafulli L,Strina D,Focarelli ML,Faggioli F,Recordati C,Scaramuzza S,Scanziani E,Mantero S,Buracchi C,Sobacchi C,Lombardo A,Naldini L,Vezzoni P,Villa A,Ficara F
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Tue Oct 13 00:00:00 EDT 2015
Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature.
Nature communications
Kolaczkowska E,Jenne CN,Surewaard BG,Thanabalasuriar A,Lee WY,Sanz MJ,Mowen K,Opdenakker G,Kubes P
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunofluorescence
Thu Mar 26 00:00:00 EDT 2015
Sunitinib depletes myeloid-derived suppressor cells and synergizes with a cancer vaccine to enhance antigen-specific immune responses and tumor eradication.
Oncoimmunology
Draghiciu O,Nijman HW,Hoogeboom BN,Meijerhof T,Daemen T
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2015
In Situ Characterization of Splenic Brucella melitensis Reservoir Cells during the Chronic Phase of Infection in Susceptible Mice.
PloS one
Hanot Mambres D,Machelart A,Vanderwinden JM,De Trez C,Ryffel B,Letesson JJ,Muraille E
13-5931 was used in Immunofluorescence to characterise B. melitensis reservoir cells to provide a better understanding of Brucella persistence in the host.
Thu May 26 00:00:00 EDT 2016
Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1.
PloS one
Szulzewsky F,Pelz A,Feng X,Synowitz M,Markovic D,Langmann T,Holtman IR,Wang X,Eggen BJ,Boddeke HW,Hambardzumyan D,Wolf SA,Kettenmann H
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2016
CARD9 Promotes Sex-Biased Colon Tumors in the APCmin Mouse Model.
Cancer immunology research
Leo VI,Tan SH,Bergmann H,Cheah PY,Chew MH,Lim KH,Ruland J,Reilly PT
13-5931-82 was used in Immunohistochemistry (Paraffin) to investigate the role of CARD9 in a mouse model of intestinal tumorigenesis, revealing that CARD9 has a sex-specific effect by reducing viability in males and promoting tumorigenesis specifically in the large intestines of male mice.
Wed Jul 01 00:00:00 EDT 2015
Host adaptation of a bacterial toxin from the human pathogen Salmonella Typhi.
Cell
Deng L,Song J,Gao X,Wang J,Yu H,Chen X,Varki N,Naito-Matsui Y,Galán JE,Varki A
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Thu Dec 04 00:00:00 EST 2014
Infection mobilizes hematopoietic stem cells through cooperative NOD-like receptor and Toll-like receptor signaling.
Cell host & microbe
Burberry A,Zeng MY,Ding L,Wicks I,Inohara N,Morrison SJ,Núñez G
13-5931 was used in Flow cytometry/Cell sorting to investigate how infection mobilises hematopoietic stem cells through cooperative NOD-like receptor and Toll-like receptor signalling.
Wed Jun 11 00:00:00 EDT 2014
Combined MEK and JAK inhibition abrogates murine myeloproliferative neoplasm.
The Journal of clinical investigation
Kong G,Wunderlich M,Yang D,Ranheim EA,Young KH,Wang J,Chang YI,Du J,Liu Y,Tey SR,Zhang X,Juckett M,Mattison R,Damnernsawad A,Zhang J,Mulloy JC,Zhang J
13-5931 was used in Flow cytometry/Cell sorting to investigate the effect of combined targeting of MEK/ERK and JAK/STAT signalling on the murine myeloproliferative neoplasm.
Sun Jun 01 00:00:00 EDT 2014
Macrophages contribute to the cyclic activation of adult hair follicle stem cells.
PLoS biology
Castellana D,Paus R,Perez-Moreno M
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Mon Dec 01 00:00:00 EST 2014
Epithelial β1 integrin is required for lung branching morphogenesis and alveolarization.
Development (Cambridge, England)
Plosa EJ,Young LR,Gulleman PM,Polosukhin VV,Zaynagetdinov R,Benjamin JT,Im AM,van der Meer R,Gleaves LA,Bulus N,Han W,Prince LS,Blackwell TS,Zent R
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunofluorescence
Mon Dec 01 00:00:00 EST 2014
Bleomycin delivery by osmotic minipump: similarity to human scleroderma interstitial lung disease.
American journal of physiology. Lung cellular and molecular physiology
Lee R,Reese C,Bonner M,Tourkina E,Hajdu Z,Riemer EC,Silver RM,Visconti RP,Hoffman S
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunofluorescence
Tue Apr 15 00:00:00 EDT 2014
Depletion of myeloid-derived suppressor cells during interleukin-12 immunogene therapy does not confer a survival advantage in experimental malignant glioma.
Cancer gene therapy
Thaci B,Ahmed AU,Ulasov IV,Wainwright DA,Nigam P,Auffinger B,Tobias AL,Han Y,Zhang L,Moon KS,Lesniak MS
13-5931 was used in Flow cytometry/Cell sorting to investigate how MDSC depletion can affect glioma immunotherapy, showing that it does not confer a survival advantage.
Wed Jan 01 00:00:00 EST 2014
Specific microbiota-induced intestinal Th17 differentiation requires MHC class II but not GALT and mesenteric lymph nodes.
Journal of immunology (Baltimore, Md. : 1950)
Geem D,Medina-Contreras O,McBride M,Newberry RD,Koni PA,Denning TL
13-5931 was used in Magnetic cell separation to investigate whether GALT and/or mesenteric lymph nodes are required for intestinal Th17 differentiation, showing that specific microbiota-induced intestinal Th17 differentiation requires MHC class II.
Tue Jul 01 00:00:00 EDT 2014
MicroRNA 21 (miR-21) and miR-181b couple with NFI-A to generate myeloid-derived suppressor cells and promote immunosuppression in late sepsis.
Infection and immunity
McClure C,Brudecki L,Ferguson DA,Yao ZQ,Moorman JP,McCall CE,El Gazzar M
13-5931 was used in Magnetic cell separation to show that sepsis reprograms myeloid cells, altering the innate immunity cell repertoire, promoting immunosuppression, while targeting miR-21 and miR-181b reverses the process.
Mon Sep 01 00:00:00 EDT 2014
Gene targeting study reveals unexpected expression of brain-expressed X-linked 2 in endocrine and tissue stem/progenitor cells in mice.
The Journal of biological chemistry
Ito K,Yamazaki S,Yamamoto R,Tajima Y,Yanagida A,Kobayashi T,Kato-Itoh M,Kakuta S,Iwakura Y,Nakauchi H,Kamiya A
13-5931 was used in Flow cytometry/Cell sorting to investigate the precise role and expression pattern of brain-expressed X-linked genes in endocrine and tissue stem/progenitor cells in mice.
Fri Oct 24 00:00:00 EDT 2014
Cervico-vaginal immunoglobulin G levels increase post-ovulation independently of neutrophils.
PloS one
Schaefer K,Brown N,Kaye PM,Lacey CJ
13-5931 was used in Flow cytometry/Cell sorting to conclude that neutrophil influx and IgG accumulation are independent events that occur in the FRT during the reproductive cycle.
Mon Apr 25 00:00:00 EDT 2016
Anti-tumor innate immunity activated by intermittent metronomic cyclophosphamide treatment of 9L brain tumor xenografts is preserved by anti-angiogenic drugs that spare VEGF receptor 2.
Molecular cancer
Doloff JC,Chen CS,Waxman DJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Thu Jun 26 00:00:00 EDT 2014
Activation of NLRP3 inflammasome by crystalline structures via cell surface contact.
Scientific reports
Hari A,Zhang Y,Tu Z,Detampel P,Stenner M,Ganguly A,Shi Y
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Tue Dec 02 00:00:00 EST 2014
Arteriolar niches maintain haematopoietic stem cell quiescence.
Nature
Kunisaki Y,Bruns I,Scheiermann C,Ahmed J,Pinho S,Zhang D,Mizoguchi T,Wei Q,Lucas D,Ito K,Mar JC,Bergman A,Frenette PS
13-5931 was used in Flow cytometry/Cell sorting to investigate the spatial localisation of quiescent haematopoietic stem cells in bone marrow, showing that arteriolar niches maintain quiescence.
Thu Oct 31 00:00:00 EDT 2013
Minor cell-death defects but reduced tumor latency in mice lacking the BH3-only proteins Bad and Bmf.
Oncogene
Baumgartner F,Woess C,Pedit V,Tzankov A,Labi V,Villunger A
13-5931 was used in Flow cytometry/Cell sorting to show that Bad and Bmf co-regulate lymphocyte homeostasis and limit spontaneous transformation in mice.
Thu Jan 31 00:00:00 EST 2013
Enhancing T lineage production in aged mice: a novel function of Foxn1 in the bone marrow niche.
Journal of immunology (Baltimore, Md. : 1950)
Zook EC,Zhang S,Gerstein RM,Witte PL,Le PT
13-5931 was used in Flow cytometry/Cell sorting to report that Foxn1 is expressed in wild-type BM and overexpressed in Foxn1Tg.
Sun Dec 01 00:00:00 EST 2013
Scmh1 has E3 ubiquitin ligase activity for geminin and histone H2A and regulates geminin stability directly or indirectly via transcriptional repression of Hoxa9 and Hoxb4.
Molecular and cellular biology
Yasunaga S,Ohtsubo M,Ohno Y,Saeki K,Kurogi T,Tanaka-Okamoto M,Ishizaki H,Shirai M,Mihara K,Brock HW,Miyoshi J,Takihara Y
13-5931 was used in Flow cytometry/Cell sorting to investigate the effects of Scmh1 on Geminin and Histone H2A, and the mechanisms therein.
Fri Feb 01 00:00:00 EST 2013
Flow cytometry analysis of murine hematopoietic stem cells.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Mayle A,Luo M,Jeong M,Goodell MA
13-5931 was used in Magnetic cell separation to discuss methods for rapid flow cytometric analysis of peripheral blood cell types and novel strategies for working with rare cell populations such as hematopoietic stem cells in the analysis of cell cycle status by BrdU, Ki-67, and Pyronin Y staining.
Tue Jan 01 00:00:00 EST 2013
Inhibiting TGFβ1 has a protective effect on mouse bone marrow suppression following ionizing radiation exposure in vitro.
Journal of radiation research
Zhang H,Wang YA,Meng A,Yan H,Wang X,Niu J,Li J,Wang H
13-5931 was used in Flow cytometry/Cell sorting to examine if the TGF1 inhibitor, SB431542, can mitigate ionizing radiation-induced bone marrow suppression, showing that inhibition has a protective effect.
Mon Jul 01 00:00:00 EDT 2013
The cardioprotective protein apolipoprotein A1 promotes potent anti-tumorigenic effects.
The Journal of biological chemistry
Zamanian-Daryoush M,Lindner D,Tallant TC,Wang Z,Buffa J,Klipfell E,Parker Y,Hatala D,Parsons-Wingerter P,Rayman P,Yusufishaq MSS,Fisher EA,Smith JD,Finke J,DiDonato JA,Hazen SL
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Fri Jul 19 00:00:00 EDT 2013
R-spondin 2 signalling mediates susceptibility to fatal infectious diarrhoea.
Nature communications
Papapietro O,Teatero S,Thanabalasuriar A,Yuki KE,Diez E,Zhu L,Kang E,Dhillon S,Muise AM,Durocher Y,Marcinkiewicz MM,Malo D,Gruenheid S
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in In Situ Hybridization (ISH)
Mon Dec 30 00:00:00 EST 2013
Ionizing radiation-induced expression of INK4a/ARF in murine bone marrow-derived stromal cell populations interferes with bone marrow homeostasis.
Blood
Carbonneau CL,Despars G,Rojas-Sutterlin S,Fortin A,Le O,Hoang T,Beauséjour CM
13-5931 was used in Flow cytometry/Cell sorting to investigate the effect of ionizing radiation on murine bone marrow-derived stromal cell populations, and overall bone marrow homeostasis.
Thu Jan 19 00:00:00 EST 2012
Thymus-autonomous T cell development in the absence of progenitor import.
The Journal of experimental medicine
Martins VC,Ruggiero E,Schlenner SM,Madan V,Schmidt M,Fink PJ,von Kalle C,Rodewald HR
13-5931 was used in Flow cytometry/Cell sorting to characterise the previously unrecognised capacity of the thymus to sustain T cell development during bone marrow progenitor deprivation.
Mon Jul 30 00:00:00 EDT 2012
Notch, Id2, and RORγt sequentially orchestrate the fetal development of lymphoid tissue inducer cells.
The Journal of experimental medicine
Cherrier M,Sawa S,Eberl G
13-5931 was used in Flow cytometry/Cell sorting to investigate the development of lymphoid tissue inducer (LTi) cells from common lymphoid progenitors (CLPs) in the fetal liver, showing that sequential changes in expression of Notch, Id2, and RORγt orchestrate the development of LTi cells.
Mon Apr 09 00:00:00 EDT 2012
Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory.
The Journal of experimental medicine
Kaji T,Ishige A,Hikida M,Taka J,Hijikata A,Kubo M,Nagashima T,Takahashi Y,Kurosaki T,Okada M,Ohara O,Rajewsky K,Takemori T
13-5931 was used in Flow cytometry/Cell sorting to reveal distinct cellular pathways that select germline-encoded and somatically mutated antibodies into immunological memory.
Mon Oct 22 00:00:00 EDT 2012
Molecular imaging of very late antigen-4 (α4β1 integrin) in the premetastatic niche.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Shokeen M,Zheleznyak A,Wilson JM,Jiang M,Liu R,Ferdani R,Lam KS,Schwarz JK,Anderson CJ
13-5931 was used in Flow cytometry/Cell sorting to study bone marrow-derived cellular expression of VEGFR1 and VLA-4 in the development of a premetastatic niche.
Tue May 01 00:00:00 EDT 2012
Differential gene expression in mice infected with distinct Toxoplasma strains.
Infection and immunity
Hill RD,Gouffon JS,Saxton AM,Su C
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2012
Myeloid-derived suppressor cells evolve during sepsis and can enhance or attenuate the systemic inflammatory response.
Infection and immunity
Brudecki L,Ferguson DA,McCall CE,El Gazzar M
13-5931 was used in Flow cytometry/Cell sorting to study myeloid-derived suppressor cell populations during early proinflammatory, late anti-inflammatory and immunosuppressive phases in a murine model of sepsis.
Fri Jun 01 00:00:00 EDT 2012
A model of GAG/MIP-2/CXCR2 interfaces and its functional effects.
Biochemistry
Rajasekaran D,Keeler C,Syed MA,Jones MC,Harrison JK,Wu D,Bhandari V,Hodsdon ME,Lolis EJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Tue Jul 17 00:00:00 EDT 2012
Preclinical evaluation of oncolytic vaccinia virus for therapy of canine soft tissue sarcoma.
PloS one
Gentschev I,Adelfinger M,Josupeit R,Rudolph S,Ehrig K,Donat U,Weibel S,Chen NG,Yu YA,Zhang Q,Heisig M,Thamm D,Stritzker J,Macneill A,Szalay AA
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunofluorescence
Thu Sep 20 00:00:00 EDT 2012
Hepatocyte-specific S100a8 and S100a9 transgene expression in mice causes Cxcl1 induction and systemic neutrophil enrichment.
Cell communication and signaling : CCS
Wiechert L,Németh J,Pusterla T,Bauer C,De Ponti A,Manthey S,Marhenke S,Vogel A,Klingmüller U,Hess J,Angel P
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunohistochemistry
Sat Dec 15 00:00:00 EST 2012
Origins and properties of dental, thymic, and bone marrow mesenchymal cells and their stem cells.
PloS one
Komada Y,Yamane T,Kadota D,Isono K,Takakura N,Hayashi S,Yamazaki H
13-5931 was used in Flow cytometry/Cell sorting to investigate whether mesechymal cells arise from neural crest or mesoderm, revealing the origins and properties of dental, thymic, and bone marrow mesenchymal cells.
Tue May 14 00:00:00 EDT 2013
Virotherapy of canine tumors with oncolytic vaccinia virus GLV-1h109 expressing an anti-VEGF single-chain antibody.
PloS one
Patil SS,Gentschev I,Adelfinger M,Donat U,Hess M,Weibel S,Nolte I,Frentzen A,Szalay AA
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Thu Mar 28 00:00:00 EDT 2013
In vivo inhibition of c-MYC in myeloid cells impairs tumor-associated macrophage maturation and pro-tumoral activities.
PloS one
Pello OM,Chèvre R,Laoui D,De Juan A,Lolo F,Andrés-Manzano MJ,Serrano M,Van Ginderachter JA,Andrés V
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Mon Feb 25 00:00:00 EST 2013
Chronic IFN-γ production in mice induces anemia by reducing erythrocyte life span and inhibiting erythropoiesis through an IRF-1/PU.1 axis.
Blood
Libregts SF,Gutiérrez L,de Bruin AM,Wensveen FM,Papadopoulos P,van Ijcken W,Ozgür Z,Philipsen S,Nolte MA
13-5931 was used in Flow cytometry/Cell sorting to reveal a molecular mechanism by which chronic exposure to IFN-γ induces expression of IRF-1 and ultimately induces anaemia.
Thu Sep 01 00:00:00 EDT 2011
Genetic deletion of chemokine receptor Ccr6 decreases atherogenesis in ApoE-deficient mice.
Circulation research
Wan W,Lim JK,Lionakis MS,Rivollier A,McDermott DH,Kelsall BL,Farber JM,Murphy PM
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Fri Aug 05 00:00:00 EDT 2011
Syndecan-4 deficiency limits neointimal formation after vascular injury by regulating vascular smooth muscle cell proliferation and vascular progenitor cell mobilization.
Arteriosclerosis, thrombosis, and vascular biology
Ikesue M,Matsui Y,Ohta D,Danzaki K,Ito K,Kanayama M,Kurotaki D,Morimoto J,Kojima T,Tsutsui H,Uede T
13-5931 was used in Flow cytometry/Cell sorting to examine whether syndecan-4 is involved in the development of neointimal formation in vivo.
Sun May 01 00:00:00 EDT 2011
Defective hematopoietic stem cell and lymphoid progenitor development in the Ts65Dn mouse model of Down syndrome: potential role of oxidative stress.
Antioxidants & redox signaling
Lorenzo LP,Chen H,Shatynski KE,Clark S,Yuan R,Harrison DE,Yarowsky PJ,Williams MS
13-5931 was used in Flow cytometry/Cell sorting to identify a link between oxidative stress and diminished IL-7Rα expression and function associated with defective haematologic development in a DS mouse model.
Sat Oct 15 00:00:00 EDT 2011
MMP9 is protective against lethal inflammatory mass lesions in the mouse colon.
Disease models & mechanisms
Hald A,Rønø B,Melander MC,Ding M,Holck S,Lund LR
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunohistochemistry
Tue Mar 01 00:00:00 EST 2011
Hepatic stellate cells function as regulatory bystanders.
Journal of immunology (Baltimore, Md. : 1950)
Ichikawa S,Mucida D,Tyznik AJ,Kronenberg M,Cheroutre H
13-5931 was used in Flow cytometry/Cell sorting to suggest that HSC can function as regulatory bystanders, and therefore, by promoting Tregs and suppressing Th17 differentiation, they might represent key players in the mechanism that drives liver-induced tolerance.
Sun May 15 00:00:00 EDT 2011
Activation of the aryl hydrocarbon receptor during pregnancy in the mouse alters mammary development through direct effects on stromal and epithelial tissues.
Biology of reproduction
Lew BJ,Manickam R,Lawrence BP
13-5931 was used in Flow cytometry/Cell sorting to determine whether activation of the aryl hydrocarbon receptor (AHR) during pregnancy modulates mammary development.
Wed Jun 01 00:00:00 EDT 2011
Online nanoflow multidimensional fractionation for high efficiency phosphopeptide analysis.
Molecular & cellular proteomics : MCP
Ficarro SB,Zhang Y,Carrasco-Alfonso MJ,Garg B,Adelmant G,Webber JT,Luckey CJ,Marto JA
13-5931 was used in Flow cytometry/Cell sorting to explore two novel multidimensional fractionation strategies for the gathering of phosphoproteomics data.
Tue Nov 01 00:00:00 EDT 2011
Basophils orchestrate chronic allergic dermatitis and protective immunity against helminths.
Immunity
Ohnmacht C,Schwartz C,Panzer M,Schiedewitz I,Naumann R,Voehringer D
13-5931 was used in Flow cytometry/Cell sorting to demonstrate that basophils play an important role for protective immunity against helminths and orchestrate chronic allergic inflammation.
Fri Sep 24 00:00:00 EDT 2010
Selective ablation of basophils in mice reveals their nonredundant role in acquired immunity against ticks.
The Journal of clinical investigation
Wada T,Ishiwata K,Koseki H,Ishikura T,Ugajin T,Ohnuma N,Obata K,Ishikawa R,Yoshikawa S,Mukai K,Kawano Y,Minegishi Y,Yokozeki H,Watanabe N,Karasuyama H
13-5931 was used in Flow cytometry/Cell sorting to investigate the cellular and molecular mechanisms underlying acquired resistance to Haemaphysalis longicornis ticks in mice.
Sun Aug 01 00:00:00 EDT 2010
Coordinate suppression of B cell lymphoma by PTEN and SHIP phosphatases.
The Journal of experimental medicine
Miletic AV,Anzelon-Mills AN,Mills DM,Omori SA,Pedersen IM,Shin DM,Ravetch JV,Bolland S,Morse HC,Rickert RC
13-5931 was used in Flow cytometry/Cell sorting to reveal that PTEN and SHIP act cooperatively to suppress B cell lymphoma and provide the first direct evidence that SHIP is a tumor suppressor.
Mon Oct 25 00:00:00 EDT 2010
Local mesenchymal stem/progenitor cells are a preferential target for initiation of adult soft tissue sarcomas associated with p53 and Rb deficiency.
The American journal of pathology
Choi J,Curtis SJ,Roy DM,Flesken-Nikitin A,Nikitin AY
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Mon Nov 01 00:00:00 EDT 2010
Local mesenchymal stem/progenitor cells are a preferential target for initiation of adult soft tissue sarcomas associated with p53 and Rb deficiency.
The American journal of pathology
Choi J,Curtis SJ,Roy DM,Flesken-Nikitin A,Nikitin AY
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Mon Nov 01 00:00:00 EDT 2010
Dendritic cells continue to capture and present antigens after maturation in vivo.
Journal of immunology (Baltimore, Md. : 1950)
Drutman SB,Trombetta ES
13-5931 was used in Magnetic cell separation to study the dynamics of Ag capture and presentation in situ, showing that dendritic cells continue to capture and present antigens after maturation.
Sun Aug 15 00:00:00 EDT 2010
Differential geminin requirement for proliferation of thymocytes and mature T cells.
Journal of immunology (Baltimore, Md. : 1950)
Karamitros D,Kotantaki P,Lygerou Z,Veiga-Fernandes H,Pachnis V,Kioussis D,Taraviras S
13-5931 was used in Magnetic cell separation to gain insight into the in vivo role of Geminin in progenitor cell division and differentiation.
Mon Mar 01 00:00:00 EST 2010
The presence of professional phagocytes dictates the number of host cells targeted for Yop translocation during infection.
Cellular microbiology
Durand EA,Maldonado-Arocho FJ,Castillo C,Walsh RL,Mecsas J
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunofluorescence
Sun Aug 01 00:00:00 EDT 2010
The presence of professional phagocytes dictates the number of host cells targeted for Yop translocation during infection.
Cellular microbiology
Durand EA,Maldonado-Arocho FJ,Castillo C,Walsh RL,Mecsas J
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunofluorescence
Sun Aug 01 00:00:00 EDT 2010
Development of immunoglobulin lambda-chain-positive B cells, but not editing of immunoglobulin kappa-chain, depends on NF-kappaB signals.
Nature immunology
Derudder E,Cadera EJ,Vahl JC,Wang J,Fox CJ,Zha S,van Loo G,Pasparakis M,Schlissel MS,Schmidt-Supprian M,Rajewsky K
13-5931 was used in Magnetic cell separation to define two distinct, consecutive phases of early B cell development that differ in their dependence on IKK-mediated NF-kappaB signaling.
Mon Jun 01 00:00:00 EDT 2009
The transcription factors STAT5A/B regulate GM-CSF-mediated granulopoiesis.
Blood
Kimura A,Rieger MA,Simone JM,Chen W,Wickre MC,Zhu BM,Hoppe PS,O'Shea JJ,Schroeder T,Hennighausen L
13-5931 was used in Flow cytometry/Cell sorting to assess the contribution of the downstream mediating transcription factors STAT5A/B to the development of granulocytes.
Thu Nov 19 00:00:00 EST 2009
Lymphoid-tissue-specific homing of bone-marrow-derived dendritic cells.
Blood
Creusot RJ,Yaghoubi SS,Chang P,Chia J,Contag CH,Gambhir SS,Fathman CG
13-5931 was used in Immunopurification to present extensive analysis of BM-DC homing to lymph nodes after intravenous and intraperitoneal inoculation.
Thu Jun 25 00:00:00 EDT 2009
Oncogenic Kras-induced leukemogeneis: hematopoietic stem cells as the initial target and lineage-specific progenitors as the potential targets for final leukemic transformation.
Blood
Zhang J,Wang J,Liu Y,Sidik H,Young KH,Lodish HF,Fleming MD
13-5931 was used in Flow cytometry/Cell sorting to examine the role and function of oncogenic KRAS mutations in the initiation and progression of leukaemia.
Thu Feb 05 00:00:00 EST 2009
Basophils preferentially express mouse Mast Cell Protease 11 among the mast cell tryptase family in contrast to mast cells.
Journal of leukocyte biology
Ugajin T,Kojima T,Mukai K,Obata K,Kawano Y,Minegishi Y,Eishi Y,Yokozeki H,Karasuyama H
13-5931 was used in Flow cytometry/Cell sorting to reveal mouse basophils rather than mast cells are the major source of mMCP-11, a trypsin-like protease.
Tue Dec 01 00:00:00 EST 2009
Inflammation recapitulates the ontogeny of lymphoid stromal cells.
Journal of immunology (Baltimore, Md. : 1950)
Peduto L,Dulauroy S,Lochner M,Späth GF,Morales MA,Cumano A,Eberl G
13-5931 was used in Flow cytometry/Cell sorting to show that LS cells are both programmed during ontogeny and reinduced during inflammation.
Fri May 01 00:00:00 EDT 2009
TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis.
Cellular immunology
Drage MG,Pecora ND,Hise AG,Febbraio M,Silverstein RL,Golenbock DT,Boom WH,Harding CV
13-5931 was used in Flow cytometry/Cell sorting to elucidate the factors governing the differential responses to MTB observed in lung antigen presenting cell subsets.
Fri Jun 12 00:00:00 EDT 2009
Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut.
Immunity
Tsuji M,Suzuki K,Kitamura H,Maruya M,Kinoshita K,Ivanov II,Itoh K,Littman DR,Fagarasan S
13-5931 was used in Flow cytometry/Cell sorting to investigate the sites and mechanisms for T cell-independent IgA synthesis.
Fri Aug 15 00:00:00 EDT 2008
A replication-defective gammaherpesvirus efficiently establishes long-term latency in macrophages but not in B cells in vivo.
Journal of virology
Li H,Ikuta K,Sixbey JW,Tibbetts SA
13-5931 was used in Flow cytometry/Cell sorting to demonstrate that a gammaherpesvirus can efficiently establish long-term latent infection in vivo in the absence of lytic replication.
Mon Sep 01 00:00:00 EDT 2008
Vaccinia virus infection modulates the hematopoietic cell compartments in the bone marrow.
Stem cells (Dayton, Ohio)
Singh P,Yao Y,Weliver A,Broxmeyer HE,Hong SC,Chang CH
13-5931 was used in Flow cytometry/Cell sorting to show that in vivo VV infection results in the expansion of c-Kit(hi)Sca-1+Lin- (KSL) haematopoietic stem cells.
Tue Apr 01 00:00:00 EDT 2008
E47 controls the developmental integrity and cell cycle quiescence of multipotential hematopoietic progenitors.
Journal of immunology (Baltimore, Md. : 1950)
Yang Q,Kardava L,St Leger A,Martincic K,Varnum-Finney B,Bernstein ID,Milcarek C,Borghesi L
13-5931 was used in Flow cytometry/Cell sorting to show E47 controls the developmental integrity and cell cycle quiescence of hematopoietic progenitors.
Sat Nov 01 00:00:00 EDT 2008
Host transmission of Salmonella enterica serovar Typhimurium is controlled by virulence factors and indigenous intestinal microbiota.
Infection and immunity
Lawley TD,Bouley DM,Hoy YE,Gerke C,Relman DA,Monack DM
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Immunofluorescence
Tue Jan 01 00:00:00 EST 2008
Combined yeast {beta}-glucan and antitumor monoclonal antibody therapy requires C5a-mediated neutrophil chemotaxis via regulation of decay-accelerating factor CD55.
Cancer research
Li B,Allendorf DJ,Hansen R,Marroquin J,Cramer DE,Harris CL,Yan J
13-5931 was used in Immunohistochemistry to show that CD55 is capable of suppressing effective immunotherapy involving administration of β-glucan and antitumour mAbs using two human xenograft models.
Wed Aug 01 00:00:00 EDT 2007
Listeria monocytogenes promotes tumor growth via tumor cell toll-like receptor 2 signaling.
Cancer research
Huang B,Zhao J,Shen S,Li H,He KL,Shen GX,Mayer L,Unkeless J,Li D,Yuan Y,Zhang GM,Xiong H,Feng ZH
Tue May 01 00:00:00 EDT 2007
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling.
Proceedings of the National Academy of Sciences of the United States of America
Tsuji M,Shinkura R,Kuroda K,Yabe D,Honjo T
13-5931-82 was used in Flow Cytometry to o investigate where and how Notch regulates early T cell differentiation by using specific up-regulation of Notch signaling by Mint knockout.
Tue Jan 30 00:00:00 EST 2007
Immature hematopoietic cells display selective requirements for adhesion- and degranulation-promoting adaptor protein in development and homeostatsis.
European journal of immunology
Dluzniewska J,Zou L,Harmon IR,Ellingson MT,Peterson EJ
13-5931-82 was used in Flow Cytometry to highlight the dynamic regulation of ADAP during T cell maturation and document expression patterns that suggest a possible role for ADAP in development of non-T hematopoietic lineages.
Thu Nov 01 00:00:00 EDT 2007
Mouse neutrophilic granulocytes express mRNA encoding the macrophage colony-stimulating factor receptor (CSF-1R) as well as many other macrophage-specific transcripts and can transdifferentiate into macrophages in vitro in response to CSF-1.
Journal of leukocyte biology
Sasmono RT,Ehrnsperger A,Cronau SL,Ravasi T,Kandane R,Hickey MJ,Cook AD,Himes SR,Hamilton JA,Hume DA
Sun Jul 01 00:00:00 EDT 2007
Mouse neutrophilic granulocytes express mRNA encoding the macrophage colony-stimulating factor receptor (CSF-1R) as well as many other macrophage-specific transcripts and can transdifferentiate into macrophages in vitro in response to CSF-1.
Journal of leukocyte biology
Sasmono RT,Ehrnsperger A,Cronau SL,Ravasi T,Kandane R,Hickey MJ,Cook AD,Himes SR,Hamilton JA,Hume DA
Sun Jul 01 00:00:00 EDT 2007
Mouse neutrophilic granulocytes express mRNA encoding the macrophage colony-stimulating factor receptor (CSF-1R) as well as many other macrophage-specific transcripts and can transdifferentiate into macrophages in vitro in response to CSF-1.
Journal of leukocyte biology
Sasmono RT,Ehrnsperger A,Cronau SL,Ravasi T,Kandane R,Hickey MJ,Cook AD,Himes SR,Hamilton JA,Hume DA
Sun Jul 01 00:00:00 EDT 2007
The mouse mammary carcinoma 4T1: characterization of the cellular landscape of primary tumours and metastatic tumour foci.
International journal of experimental pathology
DuPré SA,Redelman D,Hunter KW
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 13-5931-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2007
Hemorrhagic shock-activated neutrophils augment TLR4 signaling-induced TLR2 upregulation in alveolar macrophages: role in hemorrhage-primed lung inflammation.
American journal of physiology. Lung cellular and molecular physiology
Fan J,Li Y,Vodovotz Y,Billiar TR,Wilson MA
Sat Apr 01 00:00:00 EST 2006
Basophils play a critical role in the development of IgE-mediated chronic allergic inflammation independently of T cells and mast cells.
Immunity
Mukai K,Matsuoka K,Taya C,Suzuki H,Yokozeki H,Nishioka K,Hirokawa K,Etori M,Yamashita M,Kubota T,Minegishi Y,Yonekawa H,Karasuyama H
13-5931 was used in Flow cytometry/Cell sorting to reveal a novel basophil-induced mechanism of development of chronic allergic inflammation.
Mon Aug 01 00:00:00 EDT 2005
Delayed, asynchronous, and reversible T-lineage specification induced by Notch/Delta signaling.
Genes & development
Taghon TN,David ES,Zúñiga-Pflücker JC,Rothenberg EV
13-5931 was used in Flow cytometry/Cell sorting to study how Notch/Delta signaling is not sufficient for T-lineage specification and commitment, but can be permissive for the maintenance and proliferation of uncommitted progenitors.
Fri Apr 15 00:00:00 EDT 2005
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-RB6-8C5-RE-AV-20170920122035.jpg?time=20220826?time=20220826 "Ly-6G/Ly-6C Antibody (13-5931-82)")
