Product References
Deletion of CD36 exhibits limited impact on normal hematopoiesis and the leukemia microenvironment.
Cellular & molecular biology letters
Meng Y,Pospiech M,Ali A,Chandwani R,Vergel M,Onyemaechi S,Yaghmour G,Lu R,Alachkar H
48-5931-82 was used in Flow cytometry/Cell sorting to investigate whether targeting CD36 has any detrimental impact on normal hematopoietic cells.
Wed May 24 00:00:00 EDT 2023
Inactivation of p53 provides a competitive advantage to del(5q) myelodysplastic syndrome hematopoietic stem cells during inflammation.
Haematologica
Muto T,Walker CS,Agarwal P,Vick E,Sampson A,Choi K,Niederkorn M,Ishikawa C,Hueneman K,Varney M,Starczynowski DT
48-5931-82 was used in Flow cytometry/Cell sorting to investigate the effects of inflammation on hematopoietic stem and progenitor cells (HSPC) in the context of myelodysplastic syndromes (MDS), particularly the del(5q) subtype.
Sun Oct 01 00:00:00 EDT 2023
Maladaptive innate immune training of myelopoiesis links inflammatory comorbidities.
Cell
Li X,Wang H,Yu X,Saha G,Kalafati L,Ioannidis C,Mitroulis I,Netea MG,Chavakis T,Hajishengallis G
48-5931-82 was used in Flow cytometry/Cell sorting to show here that maladaptive BM-mediated TII underlies inflammatory comorbidities, as exemplified by the periodontitis-arthritis axis.
Thu May 12 00:00:00 EDT 2022
Maturation and specialization of group 2 innate lymphoid cells through the lung-gut axis.
Nature communications
Zhao M,Shao F,Yu D,Zhang J,Liu Z,Ma J,Xia P,Wang S
48-5931-82 was used in Flow cytometry/Cell sorting to show that ILC2s undergo translocation via the lung-gut axis upon IL-33 treatment.
Fri Dec 09 00:00:00 EST 2022
Group 3 innate lymphocytes make a distinct contribution to type 17 immunity in bladder defence.
iScience
Riding AM,Loudon KW,Guo A,Ferdinand JR,Lok LSC,Richoz N,Stewart A,Castro-Dopico T,Tuong ZK,Fiancette R,Bowyer GS,Fleming A,Gillman ES,Suchanek O,Mahbubani KT,Saeb-Parsy K,Withers D,Dougan G,Clare S,Clatworthy MR
48-5931-82 was used in Flow cytometry/Cell sorting to provide important insights into the orchestration and execution of type 17 immunity in bladder defense.
Fri Jul 15 00:00:00 EDT 2022
The microbiota regulates hematopoietic stem cell fate decisions by controlling iron availability in bone marrow.
Cell stem cell
Zhang D,Gao X,Li H,Borger DK,Wei Q,Yang E,Xu C,Pinho S,Frenette PS
48-5931-82 was used in Flow cytometry/Cell sorting to reveal an intricate interplay between the microbiota, macrophages, and iron, and their essential roles in regulating critical HSC fate decisions under stress.
Thu Feb 03 00:00:00 EST 2022
Protocol to establish a stable MLL-AF9_AML mouse model.
STAR protocols
Lu J,Zhao H,Yang L,Jiang X
48-5931-82 was used in Flow cytometry/Cell sorting to describe a mouse MLL-AF9_AML model to investigate Acute myeloid leukemia.
Fri Sep 16 00:00:00 EDT 2022
RAGE Inhibitors as Alternatives to Dexamethasone for Managing Cerebral Edema Following Brain Tumor Surgery.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Liu S,Song Y,Zhang IY,Zhang L,Gao H,Su Y,Yang Y,Yin S,Zheng Y,Ren L,Yin HH,Pillai R,Nath A,Medina EF,Cosgrove PA,Bild AH,Badie B
48-5931-82 was used in Flow cytometry/Cell sorting to study the role of the receptor for advanced glycation end products (RAGE) and its ligands on inflammatory responses to neurosurgical injury in mice and humans.
Tue Mar 01 00:00:00 EST 2022
Nonredundancy of IL-1α and IL-1β is defined by distinct regulation of tissues orchestrating resistance versus tolerance to infection.
Science advances
Eislmayr K,Bestehorn A,Morelli L,Borroni M,Vande Walle L,Lamkanfi M,Kovarik P
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Immunohistochemistry
Fri Mar 04 00:00:00 EST 2022
TRAF6 functions as a tumor suppressor in myeloid malignancies by directly targeting MYC oncogenic activity.
Cell stem cell
Muto T,Guillamot M,Yeung J,Fang J,Bennett J,Nadorp B,Lasry A,Redondo LZ,Choi K,Gong Y,Walker CS,Hueneman K,Bolanos LC,Barreyro L,Lee LH,Greis KD,Vasyliev N,Khodadadi-Jamayran A,Nudler E,Lujambio A,Lowe SW,Aifantis I,Starczynowski DT
48-5931-82 was used in Flow cytometry/Cell sorting to identify signaling states that cooperate with pre-leukemic cells and, notably, the study aimed to uncover the role of the ubiquitin ligase TRAF6 in preventing the transition from a pre-leukemic stage to overt myeloid leukemia by regulating MYC through ubiquitination and acetylation mechanisms.
Thu Feb 03 00:00:00 EST 2022
MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism.
Cancer cell
Ueda K,Kumari R,Schwenger E,Wheat JC,Bohorquez O,Narayanagari SR,Taylor SJ,Carvajal LA,Pradhan K,Bartholdy B,Todorova TI,Goto H,Sun D,Chen J,Shan J,Song Y,Montagna C,Xiong S,Lozano G,Pellagatti A,Boultwood J,Verma A,Steidl U
48-5931-82 was used in Flow cytometry/Cell sorting to identify MDMX overexpression as a pervasive preleukemic-to-AML transition mechanism in different genetically driven disease subtypes, and reveal Wnt/β-Catenin as a non-canonical MDMX-driven pathway with therapeutic potential for progression prevention and cancer interception.
Mon Apr 12 00:00:00 EDT 2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
RIPK3 Facilitates Host Resistance to Oral Toxoplasma gondii Infection.
Infection and immunity
Cervantes PW,Martorelli Di Genova B,Erazo Flores BJ,Knoll LJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Immunohistochemistry
Fri Apr 16 00:00:00 EDT 2021
BRD4-mediated repression of p53 is a target for combination therapy in AML.
Nature communications
Latif AL,Newcombe A,Li S,Gilroy K,Robertson NA,Lei X,Stewart HJS,Cole J,Terradas MT,Rishi L,McGarry L,McKeeve C,Reid C,Clark W,Campos J,Kirschner K,Davis A,Lopez J,Sakamaki JI,Morton JP,Ryan KM,Tait SWG,Abraham SA,Holyoake T,Higgins B,Huang X,Blyth K,Copland M,Chevassut TJT,Keeshan K,Adams PD
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Mon Jan 11 00:00:00 EST 2021
Design, Synthesis and Biological Evaluation of Arylpyridin-2-yl Guanidine Derivatives and Cyclic Mimetics as Novel MSK1 Inhibitors. An Application in an Asthma Model.
Molecules (Basel, Switzerland)
Bollenbach M,Nemska S,Wagner P,Camelin G,Daubeuf F,Obrecht A,Villa P,Rognan D,Bihel F,Bourguignon JJ,Schmitt M,Frossard N
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Wed Jan 13 00:00:00 EST 2021
IFNγ-Producing γ/δ T Cells Accumulate in the Fetal Brain Following Intrauterine Inflammation.
Frontiers in immunology
Lewis EL,Tulina N,Anton L,Brown AG,Porrett PM,Elovitz MA
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Wed Jan 05 00:00:00 EST 2022
Lung mesenchymal stromal cells influenced by Th2 cytokines mobilize neutrophils and facilitate metastasis by producing complement C3.
Nature communications
Zheng Z,Li YN,Jia S,Zhu M,Cao L,Tao M,Jiang J,Zhan S,Chen Y,Gao PJ,Hu W,Wang Y,Shao C,Shi Y
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Wed Oct 27 00:00:00 EDT 2021
Retinoic Acid Inhibits Tumor-Associated Mesenchymal Stromal Cell Transformation in Melanoma.
Frontiers in cell and developmental biology
Lou Q,Zhao M,Xu Q,Xie S,Liang Y,Chen J,Yuan L,Wang L,Jiang L,Mou L,Lin D,Zhao M
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Sat Apr 24 00:00:00 EDT 2021
Comprehensive mutagenesis identifies the peptide repertoire of a p53 T-cell receptor mimic antibody that displays no toxicity in mice transgenic for human HLA-A*0201.
PloS one
Trenevska I,Anderson AP,Bentley C,Hassanali T,Wiblin S,Maguire S,Pezzella F,Banham AH,Li D
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Wed Sep 29 00:00:00 EDT 2021
Abraxane-induced bone marrow CD11b+ myeloid cell depletion in tumor-bearing mice is visualized by μPET-CT with 64Cu-labeled anti-CD11b and prevented by anti-CSF-1.
Theranostics
Cao Q,Huang Q,Wang YA,Li C
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Fri Jul 23 00:00:00 EDT 2021
SPARC regulation of PMN clearance protects from pristane-induced lupus and rheumatoid arthritis.
iScience
Sangaletti S,Botti L,Gulino A,Lecis D,Bassani B,Portararo P,Milani M,Cancila V,De Cecco L,Dugo M,Tripodo C,Colombo MP
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Immunohistochemistry
Fri Jun 25 00:00:00 EDT 2021
Single-cell analyses unravel cell type-specific responses to a vitamin D analog in prostatic precancerous lesions.
Science advances
Abu El Maaty MA,Grelet E,Keime C,Rerra AI,Gantzer J,Emprou C,Terzic J,Lutzing R,Bornert JM,Laverny G,Metzger D
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Thu Jul 01 00:00:00 EDT 2021
Optimized protocol for immunophenotyping of melanoma and tumor-bearing skin from mouse.
STAR protocols
Krisna SS,Goncalves C,Gagnon N,Huang F,Plourde D,Miller WH,Fritz JH,Del Rincon SV
48-5931-82 was used in Flow cytometry/Cell sorting to determine a protocol for mouse skin isolation and immune cell isolation.
Fri Sep 17 00:00:00 EDT 2021
Construction, characterization, and immunization of nanoparticles that display a diverse array of influenza HA trimers.
PloS one
Cohen AA,Yang Z,Gnanapragasam PNP,Ou S,Dam KA,Wang H,Bjorkman PJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Fri Oct 15 00:00:00 EDT 2021
Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist.
eLife
Glassman CR,Su L,Majri-Morrison SS,Winkelmann H,Mo F,Li P,Pérez-Cruz M,Ho PP,Koliesnik I,Nagy N,Hnizdilova T,Picton LK,Kovar M,Bollyky P,Steinman L,Meyer E,Piehler J,Leonard WJ,Garcia KC
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Tue May 18 00:00:00 EDT 2021
Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist.
eLife
Glassman CR,Su L,Majri-Morrison SS,Winkelmann H,Mo F,Li P,Pérez-Cruz M,Ho PP,Koliesnik I,Nagy N,Hnizdilova T,Picton LK,Kovar M,Bollyky P,Steinman L,Meyer E,Piehler J,Leonard WJ,Garcia KC
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Tue May 18 00:00:00 EDT 2021
Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution.
Nature communications
Lima LG,Ham S,Shin H,Chai EPZ,Lek ESH,Lobb RJ,Müller AF,Mathivanan S,Yeo B,Choi Y,Parker BS,Möller A
48-5931-82 was used in Flow Cytometry to show that microenvironmental cytokines, particularly CCL2, decorate cancer exosomes via binding to surface glycosaminoglycan side chains of proteoglycans, causing exosome accumulation in specific cell subsets and organs.
Thu Jun 10 00:00:00 EDT 2021
Mitochondrial ubiquinol oxidation is necessary for tumour growth.
Nature
Martínez-Reyes I,Cardona LR,Kong H,Vasan K,McElroy GS,Werner M,Kihshen H,Reczek CR,Weinberg SE,Gao P,Steinert EM,Piseaux R,Budinger GRS,Chandel NS
48-5931 was used in Flow cytometry/Cell sorting to indicate that tumour growth requires the ETC to oxidize ubiquinol, which is essential to drive the oxidative TCA cycle and DHODH activity.
Tue Sep 01 00:00:00 EDT 2020
Adaptive response to inflammation contributes to sustained myelopoiesis and confers a competitive advantage in myelodysplastic syndrome HSCs.
Nature immunology
Muto T,Walker CS,Choi K,Hueneman K,Smith MA,Gul Z,Garcia-Manero G,Ma A,Zheng Y,Starczynowski DT
48-5931 was used in Flow cytometry/Cell sorting to show that chronic inflammation is a determinant for the competitive advantage of myelodysplastic syndrome (MDS) hematopoietic stem and progenitor cells (HSPCs) and for disease progression.
Fri May 01 00:00:00 EDT 2020
RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia.
Cell stem cell
Shen C,Sheng Y,Zhu AC,Robinson S,Jiang X,Dong L,Chen H,Su R,Yin Z,Li W,Deng X,Chen Y,Hu YC,Weng H,Huang H,Prince E,Cogle CR,Sun M,Zhang B,Chen CW,Marcucci G,He C,Qian Z,Chen J
48-5931-82 was used in Flow Cytometry to reveal crucial functions of ALKBH5 in leukemogenesis and LSC/LIC self-renewal/maintenance and highlight the therapeutic potential of targeting the ALKBH5/m6A axis.
Thu Jul 02 00:00:00 EDT 2020
Restraining Lysosomal Activity Preserves Hematopoietic Stem Cell Quiescence and Potency.
Cell stem cell
Liang R,Arif T,Kalmykova S,Kasianov A,Lin M,Menon V,Qiu J,Bernitz JM,Moore K,Lin F,Benson DL,Tzavaras N,Mahajan M,Papatsenko D,Ghaffari S
48-5931-82 was used in Flow Cytometry to investigate the overall metabolic properties of hematopoietic stem cells.
Thu Mar 05 00:00:00 EST 2020
BCG vaccination-induced emergency granulopoiesis provides rapid protection from neonatal sepsis.
Science translational medicine
Brook B,Harbeson DJ,Shannon CP,Cai B,He D,Ben-Othman R,Francis F,Huang J,Varankovich N,Liu A,Bao W,Bjerregaard-Andersen M,Schaltz-Buchholzer F,Sanca L,Golding CN,Larsen KL,Levy O,Kampmann B,Tan R,Charles A,Wynn JL,Shann F,Aaby P,Benn CS,Tebbutt SJ,Kollmann TR,Amenyogbe N
48-5931 was used in Flow cytometry/Cell sorting to show that BCG was also protective in a mouse model of neonatal polymicrobial sepsis, where it induced granulocyte colony-stimulating factor (G-CSF) within hours of administration.
Wed May 06 00:00:00 EDT 2020
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2020
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2020
In Situ Therapeutic Cancer Vaccination with an Oncolytic Virus Expressing Membrane-Tethered IL-2.
Molecular therapy oncolytics
Liu W,Dai E,Liu Z,Ma C,Guo ZS,Bartlett DL
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Fri Jun 26 00:00:00 EDT 2020
Deficiency of immunoglobulin E protects mice from experimental abdominal aortic aneurysms.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Li J,Deng Z,Zhang X,Liu F,Yang C,Shi GP
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2020
Flagellin-Stimulated Production of Interferon-β Promotes Anti-Flagellin IgG2c and IgA Responses.
Molecules and cells
Kang W,Park A,Huh JW,You G,Jung DJ,Song M,Lee HK,Kim YM
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Tue Mar 31 00:00:00 EDT 2020
Effects of Hypertonic Saline and Hydroxyethyl Starch on Myeloid-Derived Suppressor Cells in Hemorrhagic Shock Mice under Secondary Bacterial Attack.
BioMed research international
Jiang JK,Hong LJ,Lu YQ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Wed Dec 16 00:00:00 EST 2020
Long Non-Coding RNA Hotairm1 Promotes S100A9 Support of MDSC Expansion during Sepsis.
Journal of clinical & cellular immunology
Alkhateeb T,Bah I,Kumbhare A,Youssef D,Yao ZQ,McCall CE,Gazzar ME
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Sat Aug 13 00:00:00 EDT 2022
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Thu Sep 17 00:00:00 EDT 2020
Hyaluronan Degradation by Cemip Regulates Host Defense against Staphylococcus aureus Skin Infection.
Cell reports
Dokoshi T,Zhang LJ,Li F,Nakatsuji T,Butcher A,Yoshida H,Shimoda M,Okada Y,Gallo RL
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Tue Jan 07 00:00:00 EST 2020
Renal proximal tubular NEMO plays a critical role in ischemic acute kidney injury.
JCI insight
Han SJ,Williams RM,Kim M,Heller DA,D'Agati V,Schmidt-Supprian M,Lee HT
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Immunohistochemistry
Thu Sep 17 00:00:00 EDT 2020
Loss of testosterone impairs anti-tumor neutrophil function.
Nature communications
Markman JL,Porritt RA,Wakita D,Lane ME,Martinon D,Noval Rivas M,Luu M,Posadas EM,Crother TR,Arditi M
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Tue Mar 31 00:00:00 EDT 2020
Bacterial and Fungal Toll-Like Receptor Activation Elicits Type I IFN Responses in Mast Cells.
Frontiers in immunology
Kornstädt L,Pierre S,Weigert A,Ebersberger S,Schäufele TJ,Kolbinger A,Schmid T,Cohnen J,Thomas D,Ferreirós N,Brüne B,Ebersberger I,Scholich K
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Mon Jun 21 00:00:00 EDT 2021
Sensing and signaling of immunogenic extracellular RNAs restrain group 2 innate lymphoid cell-driven acute lung inflammation and airway hyperresponsiveness.
PloS one
She L,Alanazi HH,Yan L,Brooks EG,Dube PH,Xiang Y,Zhang F,Sun Y,Liu Y,Zhang X,Li XD
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Thu Sep 24 00:00:00 EDT 2020
Prevention of acute kidney injury by low intensity pulsed ultrasound via anti-inflammation and anti-apoptosis.
Scientific reports
Chiang CK,Loh JZ,Yang TH,Huang KT,Wu CT,Guan SS,Liu SH,Hung KY
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Immunohistochemistry
Mon Aug 31 00:00:00 EDT 2020
G protein-coupled receptor 68 increases the number of B lymphocytes.
American journal of blood research
He X,Feng S,Hawkins C,Lawley L,Fan W,Xu Y,Zha XM,Fang J
48-5931 was used in Flow cytometry/Cell sorting to indicate that Gpr68 expression is upregulated in hematopoietic cells upon aging and during hematopoietic regeneration that ends up with increased number of B lymphocytes.
Mon Sep 28 00:00:00 EDT 2020
TNFAIP3 Plays a Role in Aging of the Hematopoietic System.
Frontiers in immunology
Smith MA,Culver-Cochran AE,Adelman ER,Rhyasen GW,Ma A,Figueroa ME,Starczynowski DT
48-5931-82 was used in Flow Cytometry to find that the expression of A20 is significantly reduced in aged hematopoietic stem and progenitor cells (HSPC) as compared to young HSPC.
Wed Apr 28 00:00:00 EDT 2021
Protocol for Flow Cytometric Detection of Immune Cell Infiltration in the Epidermis and Dermis of a Psoriasis Mouse Model.
STAR protocols
Lou F,Sun Y,Wang H
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Fri Dec 18 00:00:00 EST 2020
The endothelial protein C receptor plays an essential role in the maintenance of pregnancy.
Science advances
Castillo MM,Yang Q,Sigala AS,McKinney DT,Zhan M,Chen KL,Jarzembowski JA,Sood R
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Immunohistochemistry
Sun Nov 01 00:00:00 EDT 2020
Human and Mouse Transcriptome Profiling Identifies Cross-Species Homology in Pulmonary and Lymph Node Mononuclear Phagocytes.
Cell reports
Leach SM,Gibbings SL,Tewari AD,Atif SM,Vestal B,Danhorn T,Janssen WJ,Wager TD,Jakubzick CV
48-5931 was used in Flow cytometry/Cell sorting to created a gene expression compendium across 24 distinct human and murine lung and lymph node mononuclear phagocyte (MP), along with human blood and murine spleen MPs, to serve as validation datasets.
Tue Nov 03 00:00:00 EST 2020
β4GALT1 controls β1 integrin function to govern thrombopoiesis and hematopoietic stem cell homeostasis.
Nature communications
Giannini S,Lee-Sundlov MM,Rivadeneyra L,Di Buduo CA,Burns R,Lau JT,Falet H,Balduini A,Hoffmeister KM
48-5931 was used in Flow cytometry/Cell sorting to identify the conserved B4galt1 gene as a critical regulator of thrombopoiesis in megakaryocytes.
Fri Jan 17 00:00:00 EST 2020
Compartmentalized gut lymph node drainage dictates adaptive immune responses.
Nature
Esterházy D,Canesso MCC,Mesin L,Muller PA,de Castro TBR,Lockhart A,ElJalby M,Faria AMC,Mucida D
48-5931-82 was used in Flow Cytometry to show drainage of gut-draining lymph nodes can resolve conflicting tolerogenic and inflammatory intestinal responses by encouraging antigen targeting to specific gut segments.
Wed May 01 00:00:00 EDT 2019
Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity.
Cell
Brown CC,Gudjonson H,Pritykin Y,Deep D,Lavallée VP,Mendoza A,Fromme R,Mazutis L,Ariyan C,Leslie C,Pe'er D,Rudensky AY
48-5931 was used in Flow cytometry/Cell sorting to identify two principal cDC2 lineages defined by distinct developmental pathways and transcriptional regulators, including T-bet and RORγt, two key transcription factors known to define innate and adaptive lymphocyte subsets.
Thu Oct 31 00:00:00 EDT 2019
Ptpn21 Controls Hematopoietic Stem Cell Homeostasis and Biomechanics.
Cell stem cell
Ni F,Yu WM,Wang X,Fay ME,Young KM,Qiu Y,Lam WA,Sulchek TA,Cheng T,Scadden DT,Qu CK
48-5931 was used in Flow cytometry/Cell sorting to show that Ptpn21 maintains cellular mechanics, which is correlated with its important functions in HSC niche retention and preservation of hematopoietic regeneration capacity.
Thu Apr 04 00:00:00 EDT 2019
TNF-α Coordinates Hematopoietic Stem Cell Survival and Myeloid Regeneration.
Cell stem cell
Yamashita M,Passegué E
48-5931 was used in Flow cytometry/Cell sorting to reveal several TNF-α-mediated pro-survival mechanisms unique to HSCs, highlight an important role for necroptosis in HSC killing, and establish TNF-α as a major pro-survival and pro-regeneration factor for HSCs.
Thu Sep 05 00:00:00 EDT 2019
Neutrophils contribute to spontaneous resolution of liver inflammation and fibrosis via microRNA-223.
The Journal of clinical investigation
Calvente CJ,Tameda M,Johnson CD,Del Pilar H,Lin YC,Adronikou N,De Mollerat Du Jeu X,Llorente C,Boyer J,Feldstein AE
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Thu Jul 11 00:00:00 EDT 2019
The role of platelets in mediating a response to human influenza infection.
Nature communications
Koupenova M,Corkrey HA,Vitseva O,Manni G,Pang CJ,Clancy L,Yao C,Rade J,Levy D,Wang JP,Finberg RW,Kurt-Jones EA,Freedman JE
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Immunocytochemistry
Tue Apr 16 00:00:00 EDT 2019
Neutrophil extracellular traps induced by VP1 contribute to pulmonary edema during EV71 infection.
Cell death discovery
Wang N,Yang X,Sun J,Sun Z,Ma Q,Wang Z,Chen Z,Wang Z,Hu F,Wang H,Zhou L,Zhang M,Xu J
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Wed Sep 30 00:00:00 EDT 2020
In Situ Modification of Tissue Stem and Progenitor Cell Genomes.
Cell reports
Goldstein JM,Tabebordbar M,Zhu K,Wang LD,Messemer KA,Peacker B,Ashrafi Kakhki S,Gonzalez-Celeiro M,Shwartz Y,Cheng JKW,Xiao R,Barungi T,Albright C,Hsu YC,Vandenberghe LH,Wagers AJ
48-5931 was used in Flow cytometry/Cell sorting to demonstrate in vivo transduction of endogenous tissue stem cells in the muscle, blood, and skin by systemic or local administration of adeno-associated viruses (AAVs) encoding genome-modifying enzymes.
Tue Apr 23 00:00:00 EDT 2019
SCGN deficiency results in colitis susceptibility.
eLife
Sifuentes-Dominguez LF,Li H,Llano E,Liu Z,Singla A,Patel AS,Kathania M,Khoury A,Norris N,Rios JJ,Starokadomskyy P,Park JY,Gopal P,Liu Q,Tan S,Chan L,Ross T,Harrison S,Venuprasad K,Baker LA,Jia D,Burstein E
48-5931-82 was used in Flow cytometry/Cell sorting to report the identification of an ultra rare missense variant (NM_006998.3:c.230G > A;p.Arg77His) in the SCGN gene causing Mendelian early-onset ulcerative colitis.
Wed Oct 30 00:00:00 EDT 2019
E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor.
Immunity
Li Q,Li D,Zhang X,Wan Q,Zhang W,Zheng M,Zou L,Elly C,Lee JH,Liu YC
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Tue Feb 20 00:00:00 EST 2018
E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor.
Immunity
Li Q,Li D,Zhang X,Wan Q,Zhang W,Zheng M,Zou L,Elly C,Lee JH,Liu YC
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Tue Feb 20 00:00:00 EST 2018
Cbl Ubiquitin Ligases Control B Cell Exit from the Germinal-Center Reaction.
Immunity
Li X,Gadzinsky A,Gong L,Tong H,Calderon V,Li Y,Kitamura D,Klein U,Langdon WY,Hou F,Zou YR,Gu H
48-5931-82 was used in Flow Cytometry to show that deleting E3 ubiquitin ligases Cbl and Cbl-b (Cbls) in GC B cells results in the early exit of high-affinity antigen-specific B cells from the GC reaction and thus impaired clonal expansion.
Tue Mar 20 00:00:00 EDT 2018
Co-inhibitory Molecule B7 Superfamily Member 1 Expressed by Tumor-Infiltrating Myeloid Cells Induces Dysfunction of Anti-tumor CD8+ T Cells.
Immunity
Li J,Lee Y,Li Y,Jiang Y,Lu H,Zang W,Zhao X,Liu L,Chen Y,Tan H,Yang Z,Zhang MQ,Mak TW,Ni L,Dong C
48-5931 was used in Flow cytometry/Cell sorting to demonstrate that increased B7S1 expression in myeloid cells from human hepatocellular carcinoma is correlated with CD8+ T cell dysfunction.
Tue Apr 17 00:00:00 EDT 2018
PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy.
Cell stem cell
Hsu JI,Dayaram T,Tovy A,De Braekeleer E,Jeong M,Wang F,Zhang J,Heffernan TP,Gera S,Kovacs JJ,Marszalek JR,Bristow C,Yan Y,Garcia-Manero G,Kantarjian H,Vassiliou G,Futreal PA,Donehower LA,Takahashi K,Goodell MA
48-5931 was used in Flow cytometry/Cell sorting to establish the clinical relevance of PPM1D mutations in clonal haematopoiesis and the importance of studying mutation-treatment interactions.
Thu Nov 01 00:00:00 EDT 2018
Loss of pleckstrin-2 reverts lethality and vascular occlusions in JAK2V617F-positive myeloproliferative neoplasms.
The Journal of clinical investigation
Zhao B,Mei Y,Cao L,Zhang J,Sumagin R,Yang J,Gao J,Schipma MJ,Wang Y,Thorsheim C,Zhao L,Stalker T,Stein B,Wen QJ,Crispino JD,Abrams CS,Ji P
48-5931 was used in Flow cytometry/Cell sorting to identify pleckstrin-2 as an effector of the JAK2/STAT5 pathway and a key factor in the pathogenesis of JAK2V617F-induced myeloproliferative neoplasms.
Tue Jan 02 00:00:00 EST 2018
Investigation of tumor-tumor interactions in a double human cervical carcinoma xenograft model in nude mice.
Oncotarget
Mertens B,Cristina de Araujo Nogueira T,Topalis D,Stranska R,Snoeck R,Andrei G
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Tue Apr 24 00:00:00 EDT 2018
Analysis of leukocyte transepithelial migration using an in vivo murine colonic loop model.
JCI insight
Flemming S,Luissint AC,Nusrat A,Parkos CA
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Immunofluorescence
Thu Oct 18 00:00:00 EDT 2018
Antiviral effects of ferric ammonium citrate.
Cell discovery
Wang H,Li Z,Niu J,Xu Y,Ma L,Lu A,Wang X,Qian Z,Huang Z,Jin X,Leng Q,Wang J,Zhong J,Sun B,Meng G
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2020
Induction of neutrophil apoptosis by a Bcl-2 inhibitor reduces particulate matter-induced lung inflammation.
Aging
Geng X,Wang X,Luo M,Xing M,Wu Y,Li W,Chen Z,Shen H,Ying S
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Tue Jun 26 00:00:00 EDT 2018
Microbiota Reconstitution Does Not Cause Bone Loss in Germ-Free Mice.
mSphere
Quach D,Collins F,Parameswaran N,McCabe L,Britton RA
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Provocative decompression causes diffuse vascular injury in mice mediated by microparticles containing interleukin-1β.
Journal of applied physiology (Bethesda, Md. : 1985)
Thom SR,Bhopale VM,Yu K,Yang M
48-5931-82 was used in Flow cytometry/Cell sorting to demonstrate that elevations of circulating MPs containing up to 9-fold higher concentrations of IL-1β occur while mice are exposed to high air pressure whereas smaller particles carrying proteins specific to exosomes are not elevated.
Mon Oct 01 00:00:00 EDT 2018
Hematopoietic stem cells can differentiate into restricted myeloid progenitors before cell division in mice.
Nature communications
Grinenko T,Eugster A,Thielecke L,Ramasz B,Krüger A,Dietz S,Glauche I,Gerbaulet A,von Bonin M,Basak O,Clevers H,Chavakis T,Wielockx B
48-5931 was used in Flow cytometry/Cell sorting to study the mechanisms that control fate decision in adult haematopoietic stem cells.s.
Tue May 15 00:00:00 EDT 2018
Notch Signaling Facilitates In Vitro Generation of Cross-Presenting Classical Dendritic Cells.
Cell reports
Kirkling ME,Cytlak U,Lau CM,Lewis KL,Resteu A,Khodadadi-Jamayran A,Siebel CW,Salmon H,Merad M,Tsirigos A,Collin M,Bigley V,Reizis B
48-5931 was used in Flow cytometry/Cell sorting to examine the role of Notch signalling in the in vitro generation of classical dendritic cells.
Tue Jun 19 00:00:00 EDT 2018
Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias.
Nature communications
Chaudhury S,O'Connor C,Cañete A,Bittencourt-Silvestre J,Sarrou E,Prendergast Á,Choi J,Johnston P,Wells CA,Gibson B,Keeshan K
48-5931 was used in Flow cytometry/Cell sorting to study paediatric acute myeloid leukaemia biology, and provide murine models that offer the potential for developing paediatric specific therapeutic strategies.
Tue Dec 11 00:00:00 EST 2018
JNK1 negatively controls antifungal innate immunity by suppressing CD23 expression.
Nature medicine
Zhao X,Guo Y,Jiang C,Chang Q,Zhang S,Luo T,Zhang B,Jia X,Hung MC,Dong C,Lin X
48-5931 was used in Flow cytometry/Cell sorting to investigate the mechanisms that negatively regulate host immune responses to a fungal infection.
Wed Mar 01 00:00:00 EST 2017
Renal Sodium Gradient Orchestrates a Dynamic Antibacterial Defense Zone.
Cell
Berry MR,Mathews RJ,Ferdinand JR,Jing C,Loudon KW,Wlodek E,Dennison TW,Kuper C,Neuhofer W,Clatworthy MR
48-5931-82 was used in Flow Cytometry to reveal a critical accessory role for the homeostatic function of a vital organ in optimizing tissue defense.
Thu Aug 24 00:00:00 EDT 2017
Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia.
Nature immunology
Fang J,Bolanos LC,Choi K,Liu X,Christie S,Akunuru S,Kumar R,Wang D,Chen X,Greis KD,Stoilov P,Filippi MD,Maciejewski JP,Garcia-Manero G,Weirauch MT,Salomonis N,Geiger H,Zheng Y,Starczynowski DT
48-5931 was used in Flow cytometry/Cell sorting to examine the significance of ubiquitin signalling in coordinating RNA processing by Toll-like receptor pathways during an immune response and in premalignant haematologic diseases.
Wed Feb 01 00:00:00 EST 2017
Gli1+ Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target.
Cell stem cell
Schneider RK,Mullally A,Dugourd A,Peisker F,Hoogenboezem R,Van Strien PMH,Bindels EM,Heckl D,Büsche G,Fleck D,Müller-Newen G,Wongboonsin J,Ventura Ferreira M,Puelles VG,Saez-Rodriguez J,Ebert BL,Humphreys BD,Kramann R
48-5931 was used in Flow cytometry/Cell sorting to study the cellular origin of bone marrow fibrosis.
Thu Jun 01 00:00:00 EDT 2017
Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity.
The Journal of experimental medicine
Thomas DC,Clare S,Sowerby JM,Pardo M,Juss JK,Goulding DA,van der Weyden L,Storisteanu D,Prakash A,Espéli M,Flint S,Lee JC,Hoenderdos K,Kane L,Harcourt K,Mukhopadhyay S,Umrania Y,Antrobus R,Nathan JA,Adams DJ,Bateman A,Choudhary JS,Lyons PA,Condliffe AM,Chilvers ER,Dougan G,Smith KG
48-5931 was used in Flow cytometry/Cell sorting to describe the key role of the previously uncharacterised protein Eros in host defence.
Mon Apr 03 00:00:00 EDT 2017
ILC2s regulate adaptive Th2 cell functions via PD-L1 checkpoint control.
The Journal of experimental medicine
Schwartz C,Khan AR,Floudas A,Saunders SP,Hams E,Rodewald HR,McKenzie ANJ,Fallon PG
48-5931 was used in Flow cytometry/Cell sorting to study how group 2 innate lymphoid cells regulate adaptive Th2 cell functions.
Mon Sep 04 00:00:00 EDT 2017
Brd4 modulates the innate immune response through Mnk2-eIF4E pathway-dependent translational control of IκBα.
Proceedings of the National Academy of Sciences of the United States of America
Bao Y,Wu X,Chen J,Hu X,Zeng F,Cheng J,Jin H,Lin X,Chen LF
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Tue May 16 00:00:00 EDT 2017
Cardiac inflammation in genetic dilated cardiomyopathy caused by MYBPC3 mutation.
Journal of molecular and cellular cardiology
Lynch TL,Ismahil MA,Jegga AG,Zilliox MJ,Troidl C,Prabhu SD,Sadayappan S
48-5931 was used in Flow cytometry/Cell sorting to show that a robust proinflammatory response occurs in the hearts of mice with dilated cardiomyopathy caused by a mutation in the cardiac myosin binding protein-C gene.
Sun Jan 01 00:00:00 EST 2017
Cardiac inflammation in genetic dilated cardiomyopathy caused by MYBPC3 mutation.
Journal of molecular and cellular cardiology
Lynch TL,Ismahil MA,Jegga AG,Zilliox MJ,Troidl C,Prabhu SD,Sadayappan S
48-5931 was used in Flow cytometry/Cell sorting to show that a robust proinflammatory response occurs in the hearts of mice with dilated cardiomyopathy caused by a mutation in the cardiac myosin binding protein-C gene.
Sun Jan 01 00:00:00 EST 2017
Silybin attenuates LPS-induced lung injury in mice by inhibiting NF-κB signaling and NLRP3 activation.
International journal of molecular medicine
Zhang B,Wang B,Cao S,Wang Y,Wu D
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2017
ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis.
RNA biology
Ben-Shoshan SO,Kagan P,Sultan M,Barabash Z,Dor C,Jacob-Hirsch J,Harmelin A,Pappo O,Marcu-Malina V,Ben-Ari Z,Amariglio N,Rechavi G,Goldstein I,Safran M
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Thu May 04 00:00:00 EDT 2017
Neutrophils Are Central to Antibody-Mediated Protection against Genital Chlamydia.
Infection and immunity
Naglak EK,Morrison SG,Morrison RP
48-5931 was used in Flow cytometry/Cell sorting to demonstrate that an IFN-γ-activated effector cell population cooperates with antibody to protect against genital chlamydia.
Sun Oct 01 00:00:00 EDT 2017
MiR-125a Is a critical modulator for neutrophil development.
PLoS genetics
Qin Y,Wu L,Ouyang Y,Zhou P,Zhou H,Wang Y,Ma J,Zhang J,Chen Y,Qian J,Tang Y,Shen N
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Sun Oct 01 00:00:00 EDT 2017
Gastric TFF1 Expression from Acute to Chronic Helicobacter Infection.
Frontiers in cellular and infection microbiology
Esposito R,Morello S,Vllahu M,Eletto D,Porta A,Tosco A
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Immunohistochemistry
Mon Jul 09 00:00:00 EDT 2018
Recipient bone marrow assimilates the myeloid/lymphoid reconstitution of distinct fetal hematopoietic stem cells.
Oncotarget
Guo XL,Chu L,Ke F,Mu LL,Li Z,Cai JJ,Li HF,Hong DL
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Tue Dec 12 00:00:00 EST 2017
BOT-4-one attenuates NLRP3 inflammasome activation: NLRP3 alkylation leading to the regulation of its ATPase activity and ubiquitination.
Scientific reports
Shim DW,Shin WY,Yu SH,Kim BH,Ye SK,Koppula S,Won HS,Kang TB,Lee KH
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Wed Nov 08 00:00:00 EST 2017
Tumor-Derived Exosomes Induce the Formation of Neutrophil Extracellular Traps: Implications For The Establishment of Cancer-Associated Thrombosis.
Scientific reports
Leal AC,Mizurini DM,Gomes T,Rochael NC,Saraiva EM,Dias MS,Werneck CC,Sielski MS,Vicente CP,Monteiro RQ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Immunohistochemistry
Tue Jul 25 00:00:00 EDT 2017
One Year Follow-Up Risk Assessment in SKH-1 Mice and Wounds Treated with an Argon Plasma Jet.
International journal of molecular sciences
Schmidt A,Woedtke TV,Stenzel J,Lindner T,Polei S,Vollmar B,Bekeschus S
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Immunofluorescence
Wed Apr 19 00:00:00 EDT 2017
Acute and chronic effects of treatment with mesenchymal stromal cells on LPS-induced pulmonary inflammation, emphysema and atherosclerosis development.
PloS one
Khedoe PPSJ,de Kleijn S,van Oeveren-Rietdijk AM,Plomp JJ,de Boer HC,van Pel M,Rensen PCN,Berbée JFP,Hiemstra PS
48-5931 was used in Flow cytometry/Cell sorting to investigate the immunomodulatory properties of MSC in acute and chronic models of lipopolysaccharide (LPS)-induced inflammation, emphysema and atherosclerosis development.
Thu Oct 12 00:00:00 EDT 2017
Combinatorial hydrogel library enables identification of materials that mitigate the foreign body response in primates.
Nature biotechnology
Vegas AJ,Veiseh O,Doloff JC,Ma M,Tam HH,Bratlie K,Li J,Bader AR,Langan E,Olejnik K,Fenton P,Kang JW,Hollister-Locke J,Bochenek MA,Chiu A,Siebert S,Tang K,Jhunjhunwala S,Aresta-Dasilva S,Dholakia N,Thakrar R,Vietti T,Chen M,Cohen J,Siniakowicz K,Qi M,McGarrigle J,Graham AC,Lyle S,Harlan DM,Greiner DL,Oberholzer J,Weir GC,Langer R,Anderson DG
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.
Cell
Damgaard RB,Walker JA,Marco-Casanova P,Morgan NV,Titheradge HL,Elliott PR,McHale D,Maher ER,McKenzie ANJ,Komander D
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Thu Aug 25 00:00:00 EDT 2016
The Spectrum and Regulatory Landscape of Intestinal Innate Lymphoid Cells Are Shaped by the Microbiome.
Cell
Gury-BenAri M,Thaiss CA,Serafini N,Winter DR,Giladi A,Lara-Astiaso D,Levy M,Salame TM,Weiner A,David E,Shapiro H,Dori-Bachash M,Pevsner-Fischer M,Lorenzo-Vivas E,Keren-Shaul H,Paul F,Harmelin A,Eberl G,Itzkovitz S,Tanay A,Di Santo JP,Elinav E,Amit I
48-5931 was used in Flow cytometry/Cell sorting to investigate the cellular states and regulatory landscapes of innate lymphoid cells.
Thu Aug 25 00:00:00 EDT 2016
Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq.
Cell
Jaitin DA,Weiner A,Yofe I,Lara-Astiaso D,Keren-Shaul H,David E,Salame TM,Tanay A,van Oudenaarden A,Amit I
48-5931 was used in Flow cytometry/Cell sorting to establish CRISP-seq as a broadly applicable, comprehensive, and unbiased approach for elucidating mammalian regulatory circuits.
Thu Dec 15 00:00:00 EST 2016
Co-inhibition of CD73 and A2AR Adenosine Signaling Improves Anti-tumor Immune Responses.
Cancer cell
Young A,Ngiow SF,Barkauskas DS,Sult E,Hay C,Blake SJ,Huang Q,Liu J,Takeda K,Teng MWL,Sachsenmeier K,Smyth MJ
48-5931 was used in Flow cytometry/Cell sorting to identify that co-blockade of the ectonucleotidase that generates adenosine CD73 and the A2A adenosine receptor that mediates adenosine signalling in leuokocytes limits tumour initiation, growth and metastasis.
Mon Sep 12 00:00:00 EDT 2016
Multiple myeloma exosomes establish a favourable bone marrow microenvironment with enhanced angiogenesis and immunosuppression.
The Journal of pathology
Wang J,De Veirman K,Faict S,Frassanito MA,Ribatti D,Vacca A,Menu E
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Wed Jun 01 00:00:00 EDT 2016
Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth.
Stem cells translational medicine
Zheng H,Zou W,Shen J,Xu L,Wang S,Fu YX,Fan W
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses.
Immunology
Xu Y,Liu Y,Yang C,Kang L,Wang M,Hu J,He H,Song W,Tang H
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Sat Oct 01 00:00:00 EDT 2016
Dendritic Cells Are Dispensable for T Cell Priming and Control of Acute Lymphocytic Choriomeningitis Virus Infection.
Journal of immunology (Baltimore, Md. : 1950)
Hilpert C,Sitte S,Matthies A,Voehringer D
48-5931 was used in Flow cytometry/Cell sorting to study the role of dendritic cells as antigen presenting cells and a source of type I interferons in acute lymphocytic choriomeningitis virus infection.
Sat Oct 01 00:00:00 EDT 2016
The miR-17∼92 cluster contributes to MLL leukemia through the repression of MEIS1 competitor PKNOX1.
Leukemia research
Mian YA,Zeleznik-Le NJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Fri Jul 01 00:00:00 EDT 2016
Trypanosoma cruzi Causes Paralyzing Systemic Necrotizing Vasculitis Driven by Pathogen-Specific Type I Immunity in Mice.
Infection and immunity
Roffê E,Marino APMP,Weaver J,Wan W,de Araújo FF,Hoffman V,Santiago HC,Murphy PM
48-5931 was used in Flow cytometry/Cell sorting to investigate T. cruzi infection as a trigger of vasculitis.
Fri Apr 01 00:00:00 EDT 2016
IFNγ is Required for Optimal Antibody-Mediated Immunity against Genital Chlamydia Infection.
Infection and immunity
Naglak EK,Morrison SG,Morrison RP
48-5931 was used in Flow cytometry/Cell sorting to examine the importance of interferon-gamma in antibody-mediated protection against chlamydia infection.
Tue Nov 01 00:00:00 EDT 2016
Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency.
Stem cell reports
Mucci A,Kunkiel J,Suzuki T,Brennig S,Glage S,Kühnel MP,Ackermann M,Happle C,Kuhn A,Schambach A,Trapnell BC,Hansen G,Moritz T,Lachmann N
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Tue Aug 09 00:00:00 EDT 2016
Activated c-Kit receptor in the heart promotes cardiac repair and regeneration after injury.
Cell death & disease
Di Siena S,Gimmelli R,Nori SL,Barbagallo F,Campolo F,Dolci S,Rossi P,Venneri MA,Giannetta E,Gianfrilli D,Feigenbaum L,Lenzi A,Naro F,Cianflone E,Mancuso T,Torella D,Isidori AM,Pellegrini M
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Thu Jul 28 00:00:00 EDT 2016
Activated c-Kit receptor in the heart promotes cardiac repair and regeneration after injury.
Cell death & disease
Di Siena S,Gimmelli R,Nori SL,Barbagallo F,Campolo F,Dolci S,Rossi P,Venneri MA,Giannetta E,Gianfrilli D,Feigenbaum L,Lenzi A,Naro F,Cianflone E,Mancuso T,Torella D,Isidori AM,Pellegrini M
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Thu Jul 28 00:00:00 EDT 2016
Influenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice.
BMC genomics
Leist SR,Pilzner C,van den Brand JM,Dengler L,Geffers R,Kuiken T,Balling R,Kollmus H,Schughart K
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Sat Feb 27 00:00:00 EST 2016
Stroke Damage Is Exacerbated by Nano-Size Particulate Matter in a Mouse Model.
PloS one
Liu Q,Babadjouni R,Radwanski R,Cheng H,Patel A,Hodis DM,He S,Baumbacher P,Russin JJ,Morgan TE,Sioutas C,Finch CE,Mack WJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Immunofluorescence
Tue Aug 23 00:00:00 EDT 2016
C/EBP homologous protein (CHOP) deficiency ameliorates renal fibrosis in unilateral ureteral obstructive kidney disease.
Oncotarget
Liu SH,Wu CT,Huang KH,Wang CC,Guan SS,Chen LP,Chiang CK
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Immunohistochemistry
Tue Apr 19 00:00:00 EDT 2016
The non-canonical Wnt receptor Ryk regulates hematopoietic stem cell repopulation in part by controlling proliferation and apoptosis.
Cell death & disease
Famili F,Perez LG,Naber BA,Noordermeer JN,Fradkin LG,Staal FJ
48-5931 was used in Flow cytometry/Cell sorting to investigate the role of the non-canonical Wnt receptor Ryk in haematopoiesis and lymphoid development.
Thu Nov 24 00:00:00 EST 2016
Stroke sensitivity in the aged: sex chromosome complement vs. gonadal hormones.
Aging
McCullough LD,Mirza MA,Xu Y,Bentivegna K,Steffens EB,Ritzel R,Liu F
48-5931 was used in Flow cytometry/Cell sorting to conclude that the sex chromosome complement contributes to ischemic sensitivity in aged animals and causes differences in innate immune responses.
Fri Jul 01 00:00:00 EDT 2016
BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis.
Nature
Canver MC,Smith EC,Sher F,Pinello L,Sanjana NE,Shalem O,Chen DD,Schupp PG,Vinjamur DS,Garcia SP,Luc S,Kurita R,Nakamura Y,Fujiwara Y,Maeda T,Yuan GC,Zhang F,Orkin SH,Bauer DE
48-5931 was used in Flow cytometry/Cell sorting to develop pooled CRISPR-Cas9 guide RNA libraries to perform in situ saturating mutagenesis of human and mouse enhancers.
Thu Nov 12 00:00:00 EST 2015
Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies.
Blood
Matthews GM,Mehdipour P,Cluse LA,Falkenberg KJ,Wang E,Roth M,Santoro F,Vidacs E,Stanley K,House CM,Rusche JR,Vakoc CR,Zuber J,Minucci S,Johnstone RW
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Thu Nov 19 00:00:00 EST 2015
A dynamic spectrum of monocytes arising from the in situ reprogramming of CCR2+ monocytes at a site of sterile injury.
The Journal of experimental medicine
Dal-Secco D,Wang J,Zeng Z,Kolaczkowska E,Wong CH,Petri B,Ransohoff RM,Charo IF,Jenne CN,Kubes P
48-5931 was used in Flow cytometry/Cell sorting to show that phenotypic conversion of monocytes during hepatic injury is essential for optimal repair.
Mon Apr 06 00:00:00 EDT 2015
A Threshold Level of Intratumor CD8+ T-cell PD1 Expression Dictates Therapeutic Response to Anti-PD1.
Cancer research
Ngiow SF,Young A,Jacquelot N,Yamazaki T,Enot D,Zitvogel L,Smyth MJ
48-5931 was used in Flow cytometry/Cell sorting to provide a framework to interrogate intra-tumour CD8(+) T-cell PD1 and immune PDL1 levels and response in human cancer.
Tue Sep 15 00:00:00 EDT 2015
The receptor for advanced glycation end products (RAGE) enhances autophagy and neutrophil extracellular traps in pancreatic cancer.
Cancer gene therapy
Boone BA,Orlichenko L,Schapiro NE,Loughran P,Gianfrate GC,Ellis JT,Singhi AD,Kang R,Tang D,Lotze MT,Zeh HJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Immunofluorescence
Mon Jun 01 00:00:00 EDT 2015
The receptor for advanced glycation end products (RAGE) enhances autophagy and neutrophil extracellular traps in pancreatic cancer.
Cancer gene therapy
Boone BA,Orlichenko L,Schapiro NE,Loughran P,Gianfrate GC,Ellis JT,Singhi AD,Kang R,Tang D,Lotze MT,Zeh HJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Immunofluorescence
Mon Jun 01 00:00:00 EDT 2015
Experimental design of complement component 5a-induced acute lung injury (C5a-ALI): a role of CC-chemokine receptor type 5 during immune activation by anaphylatoxin.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Russkamp NF,Ruemmler R,Roewe J,Moore BB,Ward PA,Bosmann M
48-5931 was used in Flow cytometry/Cell sorting to determine that the detrimental effects of C5a are partly mediated through CCR5 activation downstream of C5aR1.
Tue Sep 01 00:00:00 EDT 2015
A far-red fluorescent probe for flow cytometry and image-based functional studies of xenobiotic sequestering macrophages.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Keswani RK,Yoon GS,Sud S,Stringer KA,Rosania GR
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Local delivery of VEGF and SDF enhances endothelial progenitor cell recruitment and resultant recovery from ischemia.
Tissue engineering. Part A
Anderson EM,Kwee BJ,Lewin SA,Raimondo T,Mehta M,Mooney DJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
Reducing progression of experimental lupus nephritis via inhibition of the B7/CD28 signaling pathway.
Molecular medicine reports
Huang L,Kong Y,Wang J,Sun J,Shi Q,Qiu YH
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
The bone marrow microenvironment enhances multiple myeloma progression by exosome-mediated activation of myeloid-derived suppressor cells.
Oncotarget
Wang J,De Veirman K,De Beule N,Maes K,De Bruyne E,Van Valckenborgh E,Vanderkerken K,Menu E
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Tue Dec 22 00:00:00 EST 2015
The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia.
Nature communications
Koh HS,Chang CY,Jeon SB,Yoon HJ,Ahn YH,Kim HS,Kim IH,Jeon SH,Johnson RS,Park EJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Immunofluorescence
Fri Mar 20 00:00:00 EDT 2015
Targeted Gene Correction in Osteopetrotic-Induced Pluripotent Stem Cells for the Generation of Functional Osteoclasts.
Stem cell reports
Neri T,Muggeo S,Paulis M,Caldana ME,Crisafulli L,Strina D,Focarelli ML,Faggioli F,Recordati C,Scaramuzza S,Scanziani E,Mantero S,Buracchi C,Sobacchi C,Lombardo A,Naldini L,Vezzoni P,Villa A,Ficara F
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Tue Oct 13 00:00:00 EDT 2015
Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature.
Nature communications
Kolaczkowska E,Jenne CN,Surewaard BG,Thanabalasuriar A,Lee WY,Sanz MJ,Mowen K,Opdenakker G,Kubes P
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Immunofluorescence
Thu Mar 26 00:00:00 EDT 2015
Sunitinib depletes myeloid-derived suppressor cells and synergizes with a cancer vaccine to enhance antigen-specific immune responses and tumor eradication.
Oncoimmunology
Draghiciu O,Nijman HW,Hoogeboom BN,Meijerhof T,Daemen T
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2015
Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1.
PloS one
Szulzewsky F,Pelz A,Feng X,Synowitz M,Markovic D,Langmann T,Holtman IR,Wang X,Eggen BJ,Boddeke HW,Hambardzumyan D,Wolf SA,Kettenmann H
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2016
Severity of DSS-induced colitis is reduced in Ido1-deficient mice with down-regulation of TLR-MyD88-NF-kB transcriptional networks.
Scientific reports
Shon WJ,Lee YK,Shin JH,Choi EY,Shin DM
48-5931 was used in Flow cytometry/Cell sorting to explore the role of IDO1 in producing inflammatory responses and modulating transcriptional networks during the development of colitis.
Fri Nov 27 00:00:00 EST 2015
Sexually dimorphic outcomes and inflammatory responses in hypoxic-ischemic encephalopathy.
Journal of neuroinflammation
Mirza MA,Ritzel R,Xu Y,McCullough LD,Liu F
48-5931 was used in Flow cytometry/Cell sorting to determine HIE leads to an equivalent primary brain injury in male and female neonates that develops into sexually dimorphic outcomes in later life.
Fri Feb 20 00:00:00 EST 2015
Host adaptation of a bacterial toxin from the human pathogen Salmonella Typhi.
Cell
Deng L,Song J,Gao X,Wang J,Yu H,Chen X,Varki N,Naito-Matsui Y,Galán JE,Varki A
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Thu Dec 04 00:00:00 EST 2014
Group 2 innate lymphoid cells facilitate sensitization to local, but not systemic, TH2-inducing allergen exposures.
The Journal of allergy and clinical immunology
Gold MJ,Antignano F,Halim TY,Hirota JA,Blanchet MR,Zaph C,Takei F,McNagny KM
48-5931 was used in Flow cytometry/Cell sorting to reveal a critical role for ILC2s in the development of adaptive type 2 responses to local antigen exposure.
Tue Apr 01 00:00:00 EDT 2014
Macrophages contribute to the cyclic activation of adult hair follicle stem cells.
PLoS biology
Castellana D,Paus R,Perez-Moreno M
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Mon Dec 01 00:00:00 EST 2014
Epithelial β1 integrin is required for lung branching morphogenesis and alveolarization.
Development (Cambridge, England)
Plosa EJ,Young LR,Gulleman PM,Polosukhin VV,Zaynagetdinov R,Benjamin JT,Im AM,van der Meer R,Gleaves LA,Bulus N,Han W,Prince LS,Blackwell TS,Zent R
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Immunofluorescence
Mon Dec 01 00:00:00 EST 2014
Bleomycin delivery by osmotic minipump: similarity to human scleroderma interstitial lung disease.
American journal of physiology. Lung cellular and molecular physiology
Lee R,Reese C,Bonner M,Tourkina E,Hajdu Z,Riemer EC,Silver RM,Visconti RP,Hoffman S
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Immunofluorescence
Tue Apr 15 00:00:00 EDT 2014
Glyphosate-rich air samples induce IL-33, TSLP and generate IL-13 dependent airway inflammation.
Toxicology
Kumar S,Khodoun M,Kettleson EM,McKnight C,Reponen T,Grinshpun SA,Adhikari A
48-5931 was used in Flow cytometry/Cell sorting to explore the mechanisms of glyphosate-induced pulmonary pathology by utilising murine models and real environmental samples.
Wed Nov 05 00:00:00 EST 2014
Anti-tumor innate immunity activated by intermittent metronomic cyclophosphamide treatment of 9L brain tumor xenografts is preserved by anti-angiogenic drugs that spare VEGF receptor 2.
Molecular cancer
Doloff JC,Chen CS,Waxman DJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Thu Jun 26 00:00:00 EDT 2014
Activation of NLRP3 inflammasome by crystalline structures via cell surface contact.
Scientific reports
Hari A,Zhang Y,Tu Z,Detampel P,Stenner M,Ganguly A,Shi Y
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Tue Dec 02 00:00:00 EST 2014
FOXO3A directs a protective autophagy program in haematopoietic stem cells.
Nature
Warr MR,Binnewies M,Flach J,Reynaud D,Garg T,Malhotra R,Debnath J,Passegué E
48-5931 was used in Flow cytometry/Cell sorting to show how FOXO3A directs a protective autophagy program in haematopoietic stem cells.
Thu Feb 21 00:00:00 EST 2013
The transcription factor STAT5 is critical in dendritic cells for the development of TH2 but not TH1 responses.
Nature immunology
Bell BD,Kitajima M,Larson RP,Stoklasek TA,Dang K,Sakamoto K,Wagner KU,Kaplan DH,Reizis B,Hennighausen L,Ziegler SF
48-5931 was used in Flow cytometry/Cell sorting to investigate how type-2 immunity is affected by STAT5 transcription factor in dendritic cells.
Mon Apr 01 00:00:00 EDT 2013
miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis.
Nature cell biology
Zhang Y,Yang P,Sun T,Li D,Xu X,Rui Y,Li C,Chong M,Ibrahim T,Mercatali L,Amadori D,Lu X,Xie D,Li QJ,Wang XF
48-5931 was used in Flow cytometry/Cell sorting to investigate the role of miR-126 and miR-126* in tumour progression.
Fri Mar 01 00:00:00 EST 2013
The CSF3R T618I mutation causes a lethal neutrophilic neoplasia in mice that is responsive to therapeutic JAK inhibition.
Blood
Fleischman AG,Maxson JE,Luty SB,Agarwal A,Royer LR,Abel ML,MacManiman JD,Loriaux MM,Druker BJ,Tyner JW
48-5931 was used in Flow cytometry/Cell sorting to show that a mutation causes a lethal neutrophilic neoplasma in mice that is responsive to JAK inhibition.
Thu Nov 21 00:00:00 EST 2013
Eosinophils mediate the pathogenesis of halothane-induced liver injury in mice.
Hepatology (Baltimore, Md.)
Proctor WR,Chakraborty M,Chea LS,Morrison JC,Berkson JD,Semple K,Bourdi M,Pohl LR
48-5931 was used in Flow cytometry/Cell sorting to study how eosinophils may have a pathologic role in halothane-induced liver injury in mice.
Wed May 01 00:00:00 EDT 2013
Distinct temporal requirements for Runx1 in hematopoietic progenitors and stem cells.
Development (Cambridge, England)
Tober J,Yzaguirre AD,Piwarzyk E,Speck NA
48-5931 was used in Flow cytometry/Cell sorting to study how the requirements for Runx1 in erythroid/myeloid progenitors and hematopoietic stem cell formation are temporally distinct.
Sun Sep 01 00:00:00 EDT 2013
Infection with Francisella tularensis LVS clpB leads to an altered yet protective immune response.
Infection and immunity
Barrigan LM,Tuladhar S,Brunton JC,Woolard MD,Chen CJ,Saini D,Frothingham R,Sempowski GD,Kawula TH,Frelinger JA
48-5931 was used in Flow cytometry/Cell sorting to investigate the altered immune response induced by Francisella tularensis LVS clpB compared to Francisella tularensis LVS in vivo.
Sat Jun 01 00:00:00 EDT 2013
The cardioprotective protein apolipoprotein A1 promotes potent anti-tumorigenic effects.
The Journal of biological chemistry
Zamanian-Daryoush M,Lindner D,Tallant TC,Wang Z,Buffa J,Klipfell E,Parker Y,Hatala D,Parsons-Wingerter P,Rayman P,Yusufishaq MSS,Fisher EA,Smith JD,Finke J,DiDonato JA,Hazen SL
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Fri Jul 19 00:00:00 EDT 2013
R-spondin 2 signalling mediates susceptibility to fatal infectious diarrhoea.
Nature communications
Papapietro O,Teatero S,Thanabalasuriar A,Yuki KE,Diez E,Zhu L,Kang E,Dhillon S,Muise AM,Durocher Y,Marcinkiewicz MM,Malo D,Gruenheid S
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in In Situ Hybridization (ISH)
Mon Dec 30 00:00:00 EST 2013
Differential gene expression in mice infected with distinct Toxoplasma strains.
Infection and immunity
Hill RD,Gouffon JS,Saxton AM,Su C
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2012
A model of GAG/MIP-2/CXCR2 interfaces and its functional effects.
Biochemistry
Rajasekaran D,Keeler C,Syed MA,Jones MC,Harrison JK,Wu D,Bhandari V,Hodsdon ME,Lolis EJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Tue Jul 17 00:00:00 EDT 2012
Preclinical evaluation of oncolytic vaccinia virus for therapy of canine soft tissue sarcoma.
PloS one
Gentschev I,Adelfinger M,Josupeit R,Rudolph S,Ehrig K,Donat U,Weibel S,Chen NG,Yu YA,Zhang Q,Heisig M,Thamm D,Stritzker J,Macneill A,Szalay AA
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Immunofluorescence
Thu Sep 20 00:00:00 EDT 2012
Hepatocyte-specific S100a8 and S100a9 transgene expression in mice causes Cxcl1 induction and systemic neutrophil enrichment.
Cell communication and signaling : CCS
Wiechert L,Németh J,Pusterla T,Bauer C,De Ponti A,Manthey S,Marhenke S,Vogel A,Klingmüller U,Hess J,Angel P
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Immunohistochemistry
Sat Dec 15 00:00:00 EST 2012
Granulocytes and vascularization regulate uterine bleeding and tissue remodeling in a mouse menstruation model.
PloS one
Menning A,Walter A,Rudolph M,Gashaw I,Fritzemeier KH,Roese L
48-5931 was used in Flow cytometry/Cell sorting to investigate mechanisms underlying pathogenesis of menstrual disorders, showing that granulocytes and vascularisation regulate uterine bleeding and tissue remodelling.
Thu Jan 10 00:00:00 EST 2013
Virotherapy of canine tumors with oncolytic vaccinia virus GLV-1h109 expressing an anti-VEGF single-chain antibody.
PloS one
Patil SS,Gentschev I,Adelfinger M,Donat U,Hess M,Weibel S,Nolte I,Frentzen A,Szalay AA
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Thu Mar 28 00:00:00 EDT 2013
In vivo inhibition of c-MYC in myeloid cells impairs tumor-associated macrophage maturation and pro-tumoral activities.
PloS one
Pello OM,Chèvre R,Laoui D,De Juan A,Lolo F,Andrés-Manzano MJ,Serrano M,Van Ginderachter JA,Andrés V
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Mon Feb 25 00:00:00 EST 2013
Genetic deletion of chemokine receptor Ccr6 decreases atherogenesis in ApoE-deficient mice.
Circulation research
Wan W,Lim JK,Lionakis MS,Rivollier A,McDermott DH,Kelsall BL,Farber JM,Murphy PM
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Fri Aug 05 00:00:00 EDT 2011
STAT2 mediates innate immunity to Dengue virus in the absence of STAT1 via the type I interferon receptor.
PLoS pathogens
Perry ST,Buck MD,Lada SM,Schindler C,Shresta S
48-5931 was used in Flow cytometry/Cell sorting to determine the molecular basis of the STAT1-independent pathway that confers resistance to Dengue virus-induced disease in STAT1-deficient mice.
Tue Feb 01 00:00:00 EST 2011
MMP9 is protective against lethal inflammatory mass lesions in the mouse colon.
Disease models & mechanisms
Hald A,Rønø B,Melander MC,Ding M,Holck S,Lund LR
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Immunohistochemistry
Tue Mar 01 00:00:00 EST 2011
Interleukin-17 contributes to generation of Th1 immunity and neutrophil recruitment during Chlamydia muridarum genital tract infection but is not required for macrophage influx or normal resolution of infection.
Infection and immunity
Scurlock AM,Frazer LC,Andrews CW,O'Connell CM,Foote IP,Bailey SL,Chandra-Kuntal K,Kolls JK,Darville T
48-5931 was used in Flow cytometry/Cell sorting to investigate the role of IL-17 during C. muridarum genital tract infection.
Tue Mar 01 00:00:00 EST 2011
Basophils orchestrate chronic allergic dermatitis and protective immunity against helminths.
Immunity
Ohnmacht C,Schwartz C,Panzer M,Schiedewitz I,Naumann R,Voehringer D
48-5931 was used in Flow cytometry/Cell sorting to demonstrate that basophils play an important role for protective immunity against helminths and orchestrate chronic allergic inflammation.
Fri Sep 24 00:00:00 EDT 2010
Brain dendritic cells in ischemic stroke: time course, activation state, and origin.
Brain, behavior, and immunity
Felger JC,Abe T,Kaunzner UW,Gottfried-Blackmore A,Gal-Toth J,McEwen BS,Iadecola C,Bulloch K
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Thu Jul 01 00:00:00 EDT 2010
Local mesenchymal stem/progenitor cells are a preferential target for initiation of adult soft tissue sarcomas associated with p53 and Rb deficiency.
The American journal of pathology
Choi J,Curtis SJ,Roy DM,Flesken-Nikitin A,Nikitin AY
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Mon Nov 01 00:00:00 EDT 2010
Local mesenchymal stem/progenitor cells are a preferential target for initiation of adult soft tissue sarcomas associated with p53 and Rb deficiency.
The American journal of pathology
Choi J,Curtis SJ,Roy DM,Flesken-Nikitin A,Nikitin AY
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Mon Nov 01 00:00:00 EDT 2010
The presence of professional phagocytes dictates the number of host cells targeted for Yop translocation during infection.
Cellular microbiology
Durand EA,Maldonado-Arocho FJ,Castillo C,Walsh RL,Mecsas J
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Immunofluorescence
Sun Aug 01 00:00:00 EDT 2010
The presence of professional phagocytes dictates the number of host cells targeted for Yop translocation during infection.
Cellular microbiology
Durand EA,Maldonado-Arocho FJ,Castillo C,Walsh RL,Mecsas J
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Immunofluorescence
Sun Aug 01 00:00:00 EDT 2010
TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis.
Cellular immunology
Drage MG,Pecora ND,Hise AG,Febbraio M,Silverstein RL,Golenbock DT,Boom WH,Harding CV
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Fri Jun 12 00:00:00 EDT 2009
Host transmission of Salmonella enterica serovar Typhimurium is controlled by virulence factors and indigenous intestinal microbiota.
Infection and immunity
Lawley TD,Bouley DM,Hoy YE,Gerke C,Relman DA,Monack DM
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Immunofluorescence
Tue Jan 01 00:00:00 EST 2008
Listeria monocytogenes promotes tumor growth via tumor cell toll-like receptor 2 signaling.
Cancer research
Huang B,Zhao J,Shen S,Li H,He KL,Shen GX,Mayer L,Unkeless J,Li D,Yuan Y,Zhang GM,Xiong H,Feng ZH
Tue May 01 00:00:00 EDT 2007
Mouse neutrophilic granulocytes express mRNA encoding the macrophage colony-stimulating factor receptor (CSF-1R) as well as many other macrophage-specific transcripts and can transdifferentiate into macrophages in vitro in response to CSF-1.
Journal of leukocyte biology
Sasmono RT,Ehrnsperger A,Cronau SL,Ravasi T,Kandane R,Hickey MJ,Cook AD,Himes SR,Hamilton JA,Hume DA
Sun Jul 01 00:00:00 EDT 2007
Mouse neutrophilic granulocytes express mRNA encoding the macrophage colony-stimulating factor receptor (CSF-1R) as well as many other macrophage-specific transcripts and can transdifferentiate into macrophages in vitro in response to CSF-1.
Journal of leukocyte biology
Sasmono RT,Ehrnsperger A,Cronau SL,Ravasi T,Kandane R,Hickey MJ,Cook AD,Himes SR,Hamilton JA,Hume DA
Sun Jul 01 00:00:00 EDT 2007
Mouse neutrophilic granulocytes express mRNA encoding the macrophage colony-stimulating factor receptor (CSF-1R) as well as many other macrophage-specific transcripts and can transdifferentiate into macrophages in vitro in response to CSF-1.
Journal of leukocyte biology
Sasmono RT,Ehrnsperger A,Cronau SL,Ravasi T,Kandane R,Hickey MJ,Cook AD,Himes SR,Hamilton JA,Hume DA
Sun Jul 01 00:00:00 EDT 2007
The mouse mammary carcinoma 4T1: characterization of the cellular landscape of primary tumours and metastatic tumour foci.
International journal of experimental pathology
DuPré SA,Redelman D,Hunter KW
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 48-5931-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2007
Hemorrhagic shock-activated neutrophils augment TLR4 signaling-induced TLR2 upregulation in alveolar macrophages: role in hemorrhage-primed lung inflammation.
American journal of physiology. Lung cellular and molecular physiology
Fan J,Li Y,Vodovotz Y,Billiar TR,Wilson MA
Sat Apr 01 00:00:00 EST 2006
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-RB6-8C5-RE-AV-20170920122035.jpg?time=20240507?time=20240507 "Ly-6G/Ly-6C Antibody (48-5931-82)")
