| Bavlovic J, et al.(2023) Intact O-antigen is critical structure for the exceptional tubular shape of outer membrane vesicles in Francisella tularensis.Microbiol Res 269:127300. | 2023 | 微生物およびモデル生物 | |
| Delaunay JL, et al.(2023) Ivacaftor-Mediated Potentiation of ABCB4 Missense Mutations Affecting Critical Motifs of the NBDs: Repositioning Perspectives for Hepatobiliary Diseases.Int J Mol Sci 24(2):1236. | 2023 | その他 | |
| Losada JZ, et al.(2023) Apoptosis-modulatory miR-361-3p as a novel treatment target in endocrine-resistant breast cancer.J Endocrinol Jan 1 doi: 10.1530/JOE-22-0229. | 2023 | がん研究 | 乳がん |
| Thangavel H, et al.(2023) Susceptibility of Fat Tissue to SARS-CoV-2 Infection in Female hACE2 Mouse Model.Int J Mol Sci 24(2):1314. | 2023 | 細胞シグナル伝達 | |
| Gamage CDB, et al.(2023) Libertellenone T, a Novel Compound Isolated from Endolichenic Fungus, Induces G2/M Phase Arrest, Apoptosis, and Autophagy by Activating the ROS/JNK Pathway in Colorectal Cancer Cells.Cancers (Basel) 15(2):489. | 2023 | がん研究 | 大腸がん |
| Zhang X, et al.(2023) Oridonin Induces Apoptosis in Esophageal Squamous Cell Carcinoma by Inhibiting Cytoskeletal Protein LASP1 and PDLIM1.Molecules 28(2):805. | 2023 | がん研究 | 扁平上皮がん |
| Petazzi P, et al.(2023) Global Impairment of Immediate-Early Genes Expression in Rett Syndrome Models and Patients Linked to Myelination Defects.Int J Mol Sci 24(2):1453. | 2023 | 神経生物学 | |
| Oswal N, et al.(2023) Diets Differently Regulate Pulmonary Pathogenesis and Immune Signaling in Mice during Acute and Chronic Mycobacterium tuberculosis Infection.Life (Basel) 13(1):228. | 2023 | 微生物およびモデル生物 | |
| Hsu CL, et al.(2023) Neuroprotective Effects of Erinacine A on an Experimental Model of Traumatic Optic Neuropathy.Int J Mol Sci 24(2):1504. | 2023 | 神経生物学 | |
| Chernikov IV, et al.(2023) siRNA-Mediated Timp1 Silencing Inhibited the Inflammatory Phenotype during Acute Lung Injury.Int J Mol Sci 24(2):1641. | 2023 | その他 | |
| Forte E, et al.(2023) Critical Role for the Human Cytomegalovirus Major Immediate Early Proteins in Recruitment of RNA Polymerase II and H3K27Ac To an Enhancer-Like Element in Ori Lyt.Microbiol Spectr Jan 16 doi: 10.1128/spectrum.03144-22. | 2023 | その他 | |
| Südfeld C, et al.(2023) Expression of glycerol-3-phosphate acyltransferase increases non-polar lipid accumulation in Nannochloropsis oceanica.Microb Cell Fact 22(1):12. | 2023 | その他 | |
| Sloas DC, et al.(2023) Tension-tuned receptors for synthetic mechanotransduction and intercellular force detection.Nat Biotechnol Jan 16 doi: 10.1038/s41587-022-01638-y. | 2023 | メソッド開発 | |
| Kong Y, et al.(2023) HIF2α activation and mitochondrial deficit due to iron chelation cause retinal atrophy.EMBO Mol Med Jan 16 doi: 10.15252/emmm.202216525. | 2023 | その他 | |
| Che Y, et al.(2023) Bile acids target mitofusin 2 to differentially regulate innate immunity in physiological versus cholestatic conditions.Cell Rep 42(1):112011. | 2023 | Mitochondrial studies | |
| Yoshida M, et al.(2023) An antisense amido-bridged nucleic acid gapmer oligonucleotide targeting SRRM4 alters REST splicing and exhibits anti-tumor effects in small cell lung cancer and prostate cancer cells.Cancer Cell Int 23(1):8. | 2023 | がん研究 | 肺がん |
| Woodburn SC, et al.(2023) Depletion of microglial BDNF increases susceptibility to the behavioral and synaptic effects of chronic unpredictable stress.Brain Behav Immun Jan 18 doi: 10.1016/j.bbi.2023.01.014. | 2023 | 神経生物学 | |
| Shang J, et al.(2023) Inhibition of Klf10 Attenuates Oxidative Stress-Induced Senescence of Chondrocytes via Modulating Mitophagy.Molecules 28(3)924. | 2023 | 薬剤機構 | |
| Silva RM, et al.(2023) Anion exchange chromatography-based platform for the scalable purification of extracellular vesicles derived from human mesenchymal stromal cells.Sep Purif Technol 310:123238. | 2023 | メソッド開発 | |
| Foliaki ST, et al.(2023) Altered energy metabolism in Fatal Familial Insomnia cerebral organoids is associated with astrogliosis and neuronal dysfunction.PLoS Genet 19(1):e1010565. | 2023 | 神経生物学 | |
| Jung YH, et al.(2023) A conformation-selective protein binder for a KRAS mutant inhibits the interaction between RAS and RAF.Biochem Biophys Res Commun 645:110-117. | 2023 | 構造生物学／タンパク質相互作用 | |
| Wang W, et al.(2023) The impact of osmotic stresses on the biofilm formation, immunodetection, and morphology of Aeromonas hydrophila.Microbiol Res 269:127301. | 2023 | 微生物およびモデル生物 | |
| Morales A, et al.(2023) PACAP and acetylcholine cause distinct Ca2+ signals and secretory responses in chromaffin cells.J Gen Physiol 155(2):e202213180. | 2023 | 細胞シグナル伝達 | |
| Ebelt ND and Manuel ER (2023) 5-Azacytidine-Mediated Modulation of the Immune Microenvironment in Murine Acute Myeloid Leukemia.Cancers 15(1):118. | 2023 | がん研究 | 一般 |
| AlZahrani S, et al.(2023) Anti-Inflammatory Effect of Specialized Proresolving Lipid Mediators on Mesenchymal Stem Cells: An In Vitro Study.Cells 12(1):122. | 2023 | 幹細胞 | |
| Wang L, et al.(2023) Nicotinamide Mononucleotide Ameliorates Silica-Induced Lung Injury through the Nrf2-Regulated Glutathione Metabolism Pathway in Mice.Nutrients 15(1): 143. | 2023 | その他 | |
| Kim YK, et al.(2023) Transcriptome Profile in the Mouse Brain of Hepatic Encephalopathy and Alzheimer's Disease.Int. J. Mol.Sci 24(1): 675. | 2023 | 神経生物学 | |
| Marianna B, et al.(2023) Design, Synthesis and Antiproliferative Evaluation of Bis-Indole Derivatives with a Phenyl Linker: Focus on Autophagy.Molecules 28(1): 251. | 2023 | がん研究 | 肺がん |
| Kim JY, et al.(2023) Antioxidant, Anti-Apoptotic, and Anti-Inflammatory Effects of Farrerol in a Mouse Model of Obstructive Uropathy.Curr.Issues Mol.Biol 45(1): 337-352. | 2023 | 薬剤機構 | |
| Montero‐Blay A, et al.(2023) Bacterial expression of a designed single‐chain IL‐10 prevents severe lung inflammation.Mol Syst Biol Jan 4 doi: 10.15252/msb.202211037. | 2023 | 薬剤機構 | |
| Thangavel H, et al.(2023) Diets Differently Regulate Tumorigenesis in Young E0771 Syngeneic Breast Cancer Mouse Model.J. Clin.Med 12(2): 413. | 2023 | がん研究 | 乳がん |
| Verma A, et al.(2023) P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress.Int. J. Mol.Sci 24(2):950. | 2023 | Mitochondrial studies | |
| Sokanovic SJ, et al.(2023) Common and female-specific roles of protein tyrosine phosphatase receptors N and N2 in mice reproduction.Sci Rep 13(1):355. | 2023 | その他 | |
| Hung SH, et al.(2023) Structural basis of Qng1-mediated salvage of the micronutrient queuine from queuosine-5′-monophosphate as the biological substrate.Nucleic Acids Res Jan 5 doi: 10.1093/nar/gkac1231. | 2023 | その他 | |
| Alway SE, et al.(2023) Mitochondria transplant therapy improves regeneration and restoration of injured skeletal muscle.J Cachexia Sarcopenia Muscle Jan 5 doi: 10.1002/jcsm.13153. | 2023 | Mitochondrial studies | |
| Nielsen SSE, et al.(2023) Apicobasal transferrin receptor localization and trafficking in brain capillary endothelial cells.Fluids Barriers CNS 20(1):2. | 2023 | 神経生物学 | |
| Woo JH, et al.(2023) Polypropylene nanoplastic exposure leads to lung inflammation through p38-mediated NF-κB pathway due to mitochondrial damage.Part Fibre Toxicol 20(1):2. | 2023 | Mitochondrial studies | |
| Itoh T, et al.(2023) Phenolic Glycosides Citrulluside H and Citrulluside T Isolated From Young Watermelon (Citrullus lanatus) Fruit Have Beneficial Effects Against Cutibacterium acnes-Induced Skin Inflammation.Natural Product Communications 18(1). | 2023 | 植物科学 | |
| Chen TW, et al.(2022) Vitamin B3 Provides Neuroprotection via Antioxidative Stress in a Rat Model of Anterior Ischemic Optic Neuropathy.Antioxidants (Basel) 11(12):2422. | 2022 | 神経生物学 | |
| Dorajoo R, et al.(2022) Vascular smooth muscle cells in low SYNTAX scores coronary artery disease exhibit proinflammatory transcripts and proteins correlated with IL1B activation.Atherosclerosis Dec 17 doi: 10.1016/j.atherosclerosis.2022.12.005. | 2022 | その他 | |
| Ceyzériat K, et al.(2022) Low-dose brain irradiation normalizes TSPO and CLUSTERIN levels and promotes the non-amyloidogenic pathway in pre-symptomatic TgF344-AD rats.J Neuroinflammation 19(1):311. | 2022 | 神経生物学 | |
| Erzurumlu Y, et al.(2022) 1, 25 (OH) 2 D3 induced vitamin D receptor signaling negatively regulates endoplasmic reticulum-associated degradation (ERAD) and androgen receptor signaling in human prostate cancer cells.Cell Signal Dec 22 doi: 10.1016/j.cellsig.2022.110577. | 2022 | 細胞シグナル伝達 | |
| van Vliet VJE, et al.(2022) Ubiquitin variants potently inhibit SARS-CoV-2 PLpro and viral replication via a novel site distal to the protease active site.PLoS Pathog 18(12):e1011065. | 2022 | 微生物およびモデル生物 | |
| Sato T, et al.(2022) Fibrosis resolution in the mouse liver: role of Mmp12 and potential role of Calpain ½.Matrix Biol Plus 17: 100127. | 2022 | その他 | |
| Chen J, et al.(2022) Building bioorthogonal click-release capable artificial receptors on cancer cell surface for imaging, drug targeting and delivery.Acta Pharm Sin B. Dec 28 doi: 10.1016/j.apsb.2022.12.018. | 2022 | がん研究 | 一般 |
| Li Z, et al.(2022) Sodium para-aminosalicylic acid ameliorates brain neuroinflammation and behavioral deficits in juvenile lead-exposed rats by modulating MAPK signaling pathway and alpha-synuclein.Toxicol Lett Dec 28 doi: 10.1016/j.toxlet.2022.12.013. | 2022 | 神経生物学 | |
| Cesaro G, et al.(2022) Trypanosoma brucei RRP44: a versatile enzyme for processing structured and non-structured RNA substrates.Nucleic Acids Res Dec 30 doi: 10.1093/nar/gkac1199. | 2022 | その他 | |
| Shiohara A, et al.(2022) SARS‐CoV‐2 Virus Detection Via a Polymeric Nanochannel‐Based Electrochemical Biosensor.Small Dec 30 doi: 10.1002/smll.202205281. | 2022 | メソッド開発 | |
| Chan K, et al.(2022) Survival-based CRISPR genetic screens across a panel of permissive cell lines identify common and cell-specific SARS-CoV-2 host factors.Heliyon Dec 30 doi: 10.1016/j.heliyon.2022.e12744. | 2022 | CRISPR | |
| Seo S, et al.(2022) Neuro‐Glia‐Vascular‐on‐a‐Chip System to Assess Aggravated Neurodegeneration via Brain Endothelial Cells upon Exposure to Diesel Exhaust Particles.Adv Funct Mater Dec 20 doi: 10.1002/adfm.202210123. | 2022 | 神経生物学 | |
| Alejaldre L, et al.(2022) Tuning Selectivity in CalA Lipase: Beyond Tunnel Engineering.Biochemistry Dec 29 doi: 10.1021/acs.biochem.2c00513. | 2022 | その他 | |
| Kang H, et al.(2022) DGKB mediates radioresistance by regulating DGAT1-dependent lipotoxicity in glioblastoma.Cell Rep Med Dec 22 doi: 10.1016/j.xcrm.2022.100880. | 2022 | がん研究 | 脳腫瘍 |
| Zhu Y and Hart GW (2022) Dual-specificity RNA aptamers enable manipulation of target-specific O-GlcNAcylation and unveil functions of O-GlcNAc on β-catenin.Cell Dec 30 doi: 10.1016/j.cell.2022.12.016. | 2022 | メソッド開発 | |
| Saghaug C, et al.(2022) Genetic diversity in the metronidazole metabolism genes nitroreductases and pyruvate ferredoxin oxidoreductases in susceptible and refractory clinical samples of Giardia lamblia.Int J Parasitol Drugs Drug Resist 21:51-60. | 2022 | 微生物およびモデル生物 | |
| Bayaraa O, et al.(2022) Nanoceria-GO-intercalated multicellular spheroids revascularize and salvage critical ischemic limbs through anti-apoptotic and pro-angiogenic functions.Biomaterials Nov 14 doi: 10.1016/j.biomaterials.2022.121914. | 2022 | 細胞シグナル伝達 | |
| Zekri-Nechar K, et al.(2022) Spike Protein Subunits of SARS-CoV-2 Alter Mitochondrial Metabolism in Human Pulmonary Microvascular Endothelial Cells: Involvement of Factor Xa.Dis Markers Nov 18 doi: 10.1155/2022/1118195. | 2022 | Mitochondrial studies | |
| Kim H, et al.(2022) Simultaneous Quantification of Apolipoprotein C-III O-Glycoforms by Protein-MRM.J Proteome Res Nov 21 doi: 10.1021/acs.jproteome.2c00490. | 2022 | 構造生物学／タンパク質相互作用 | |
| Wu MY, et al.(2022) Role of non-neuronal cholinergic system in the early stage response of epithelial-mesenchymal transformation related markers in A549 cells induced by coal particles.Heliyon 8(11):e11751. | 2022 | 疾病研究 | バイオマーカー研究 |
| Jacquet S, et al.(2022) Adaptive duplication and genetic diversification of protein kinase R contribute to the specificity of bat-virus interactions.Sci Adv 8(47):eadd7540. | 2022 | 疾病研究 | バイオマーカー研究 |
| Underwood J, et al.(2022) Anaplasma phagocytophilum Transmission Activates Immune Pathways While Repressing Wound Healing in the Skin.Life 12(12): 1965. | 2022 | その他 | |
| Piras R, et al.(2022) circCsnk1g3-and circAnkib1-regulated interferon responses in sarcoma promote tumorigenesis by shaping the immune microenvironment.Nat Commun 13(1):7243. | 2022 | がん研究 | 一般 |
| Palomar-Siles M, et al.(2022) Translational readthrough of nonsense mutant TP53 by mRNA incorporation of 5-Fluorouridine.Cell Death Dis 13(11):997. | 2022 | がん研究 | 一般 |
| Park JH, et al.(2022) Protective Effects of Carnosol on Renal Interstitial Fibrosis in a Murine Model of Unilateral Ureteral Obstruction.Antioxidants 11(12): 2341. | 2022 | その他 | |
| Haynes KA, et al.(2023) Rapid Single-Pot Assembly of Modular Chromatin Proteins for Epigenetic Engineering.Methods Mol Biol 2599:191-214. | 2023 | メソッド開発 | |
| Piel S, et al.(2022) Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning.Sci Rep 12(1):20329. | 2022 | Mitochondrial studies | |
| Idrees M, et al.(2022) Cycloastragenol activation of Telomerase improves β-Klotho protein level and attenuates age-related malfunctioning in ovarian tissues.Mech Ageing Dev Nov 30 doi: 10.1016/j.mad.2022.111756. | 2022 | その他 | |
| Pan B, et al.(2022) MiR-148a deletion protects from bone loss in physiological and estrogen-deficient mice by targeting NRP1.Cell Death Discov 8(1):470. | 2022 | その他 | |
| Duan X, et al.(2022) Novel Loss of Function (G15D) Mutation on RAC2 in a Family with Combined Immunodeficiency and Increased Levels of Immunoglobulin G, A, and E. J Clin Immunol Dec 2 doi: 10.1007/s10875-022-01411-5. | 2022 | その他 | |
| Kim J, et al.(2022) One‐step Preparation of an Injectable Hydrogel Scaffold System Capable of Sequential Dual‐growth Factor Release to Maximize Bone Regeneration.Adv Healthc Mater Dec 1 doi: 10.1002/adhm.202202401. | 2022 | 幹細胞 | |
| Ekundayo B, et al.(2022) Structural insights into the regulation of Cas7-11 by TPR-CHAT.Nat Struct Mol Biol Dec 5 doi: 10.1038/s41594-022-00894-5. | 2022 | 構造生物学／タンパク質相互作用 | |
| Nguyen H, et al.(2023) Impact of physiological media and sterilization methods on the physicochemical characteristics of engineered CNCs, and the effects on nanomaterial-protein interactions and immunological activity.Colloid Interface Sci Commun 52: 100684. | 2023 | 構造生物学／タンパク質相互作用 | |
| Reguigui A, et al.(2022) Nine-dimensional bioprofiles of Tunisian sages (Salvia officinalis, S. aegyptiaca and S. verbenaca) by high-performance thin-layer chromatography–effect-directed analyses.J Chromatogr A Dec 7 doi: 10.1016/j.chroma.2022.463704. | 2022 | 植物科学 | |
| Ceccacci S, et al.(2022) Jasminum sambac Cell Extract as Antioxidant Booster against Skin Aging.Antioxidants 11(12): 2409. | 2022 | その他 | |
| Cheng D, et al.(2022) Emodin Alleviates Arthritis Pain through Reducing Spinal Inflammation and Oxidative Stress.Mol Pain Dec 6 doi: 10.1177/17448069221146398. | 2022 | その他 | |
| Beker M, et al.(2022) Dual action of exosomes derived from in vitro Aβ toxicity model: the role of age for pathological response.Arch Gerontol Geriatr 106:104874. | 2022 | 神経生物学 | |
| Barilli A, et al.(2022) Growth Arrest of Alveolar Cells in Response to Cytokines from Spike S1-Activated Macrophages: Role of IFN-γ.Biomedicines 10 3085. | 2022 | 細胞シグナル伝達 | |
| Yoon SH, et al.(2022) Comparative study of lung toxicity of E-cigarette ingredients to investigate E-cigarette or Vaping Product associated Lung Injury.J Hazard Mater 445: 130454. | 2022 | その他 | |
| Chen X, et al.(2022) Liensinine, an Isoquinoline-Type Alkaloid in Lotus Seeds, Suppressed TGF-beta1-Induced Proliferation and Migration in Human Tenon Capsule Fibroblast Cells Through MAP3K7 Gene.Rev. Bras.Farmacogn Dec 6 doi: 10.1007/s43450-022-00334-x. | 2022 | 細胞シグナル伝達 | |
| Vetrovoy O, et al.(2022) Prenatal Hypoxia-Induced Adverse Reaction to Mild Stress is Associated with Depressive-Like Changes in the Glucocorticoid System of Rats.Neurochem Res Dec 10 doi: 10.1007/s11064-022-03837-0. | 2022 | 神経生物学 | |
| Senthilvelan A, et al.(2022) Click-iT Trinucleotide Cap Analog: Synthesis, mRNA Translation, and Detection.Bioorg Med Chem 77:117128. | 2022 | メソッド開発 | |
| Shao W, et al.(2022) Expression of fibrinogen-like protein 2 (Fgl2) on Toll-like receptor 9 (TLR9) expression in autoimmune myelitis.Int Immunopharmacol 114:109539. | 2022 | 細胞シグナル伝達 | |
| Yang W, et al.(2022) Thermophilic archaeon orchestrates temporal expression of GDGT ring synthases in response to temperature and acidity stress.Environ Microbiol Dec 10 doi: 10.1111/1462-2920.16301. | 2022 | 微生物およびモデル生物 | |
| Digby EM, et al.(2022) Photocaged DNA-Binding Photosensitizer Enables Photocontrol of Nuclear Entry for Dual-Targeted Photodynamic Therapy.J Med Chem 65(24):16679-16694. | 2022 | 薬剤機構 | |
| Ji M, et al.(2022) Sirt6 attenuates chondrocyte senescence and osteoarthritis progression.Nat Commun 13(1):7658. | 2022 | 細胞シグナル伝達 | |
| Singh S, et al.(2022) Butyrate Ameliorates Intraocular Bacterial Infection by Promoting Autophagy and Attenuating the Inflammatory Response.Infect Immun Dec 14 doi: 10.1128/iai.00252-22. | 2022 | 細胞シグナル伝達 | |
| Smart K, et al.(2022) Fidgetin-like 2 depletion enhances cell migration by regulating GEF-H1, RhoA, and FAK.Biophys J Dec 15 doi: 10.1016/j.bpj.2022.12.018. | 2022 | その他 | |
| Wang YF, et al.(2022) Endoplasmic reticulum stress regulates autophagic response that is involved in Saikosaponin a-induced liver cell damage.Toxicol In Vitro Dec 17 doi: 10.1016/j.tiv.2022.105534. | 2022 | その他 | |
| Yang M, et al.(2022) Transcorneal but not transpalpebral electrical stimulation disrupts mucin homeostasis of the ocular surface.BMC Ophthalmol 22(1):490. | 2022 | 神経生物学 | |
| Niwa R, et ail (2022) Experimental model of micronodular thymic neoplasm with lymphoid stroma.Thorac Cancer Dec 16 doi: 10.1111/1759-7714.14716. | 2022 | がん研究 | 一般 |
| Chen Y, et al.(2022) E2F1-mediated up-regulation of TOP2A promotes viability, migration, and invasion, and inhibits apoptosis of gastric cancer cells.J Biosci 47:84. | 2022 | がん研究 | 胃がん |
| Degnan RM, et al.(2022) Exogenous double‐stranded RNA inhibits the infection physiology of rust fungi to reduce symptoms in planta.Mol Plant Pathol Dec 17 doi: 10.1111/mpp.13286. | 2022 | 植物科学 | |
| Luan Y, et al.(2022) TAp63 determines the fate of oocytes against DNA damage.Sci Adv 8(51):eade1846. | 2022 | 細胞シグナル伝達 | |
| Lee HL, et al.(2023) Anti-Amnesic Effect of Synbiotic Supplementation Containing Corni fructus and Limosilactobacillus reuteri in DSS-Induced Colitis Mice.Int Mol Sci 24(1):90. | 2023 | その他 | |
| Yan Y, et al.(2022) Thalamocortical Circuit Controls Neuropathic Pain via Up-regulation of HCN2 in the Ventral Posterolateral Thalamus.Neurosci Bull Dec 20 doi: 10.1007/s12264-022-00989-5. | 2022 | 神経生物学 | |
| Okawa M, et al.(2022) Extracellular matrix-inspired hydrogel of hyaluronan and gelatin crosslinked via a Link module with a transglutaminase reactive sequence.Commun Mater 3: 81. | 2022 | その他 | |
| Jousma J, et al.(2022) Alteration of the N6-methyladenosine epitranscriptomic profile in synthetic phthalate-treated human induced pluripotent stem cell-derived endothelial cells.Epigenomics Oct 31 doi: 10.2217/epi-2022-0110. | 2022 | 疾病研究 | バイオマーカー研究 |
| Liang W, et al.(2022) Prolactin-Induced Protein facilitates corneal wound healing.Exp Eye Res 225:109300. | 2022 | その他 | |
| Dong ZB, et al.(2022) 2-Bromopalmitate decreases spinal inflammation and attenuates oxaliplatin-induced neuropathic pain via reducing Drp1-mediated mitochondrial dysfunction.PLoS One 17(10):e0275428. | 2022 | がん研究 | 一般 |
| Wang TC, et al.(2022) Inflammation-Regulated Nanodrug Sensitizes Hepatocellular Carcinoma to Checkpoint Blockade Therapy by Reprogramming the Tumor Microenvironment.ACS Appl Mater Interfaces Oct 31 doi: 10.1021/acsami.2c14448. | 2022 | がん研究 | 肝臓がん |
| Wu Z, et al.(2022) ALDH3B1 protects interfollicular epidermal cells against lipid peroxidation via the NRF2 pathway.Cell Stress Chaperones Nov 3 doi: 10.1007/s12192-022-01306-9. | 2022 | 細胞シグナル伝達 | |
| Qu X, et al.(2022) Solamargine Alleviates Proliferation and Metastasis of Cervical Cancer Cells by Blocking the CXCL3-Mediated Erk Signaling Pathway.Evid Based Complement Alternat Med Oct 29 doi: 10.1155/2022/7634754. | 2022 | がん研究 | 一般 |
| Liu L, et al.(2022) Fibroblast growth factor 10 protects against particulate matter-induced lung injury by inhibiting oxidative stress-mediated pyroptosis via the PI3K/Akt/Nrf2 signaling pathway.Int Immunol 113: 109398. | 2022 | 細胞シグナル伝達 | |
| Chrystal PW, et al.(2022) The inner junction protein CFAP20 functions in motile and non-motile cilia and is critical for vision.Nat Commun 13(1):6595. | 2022 | その他 | |
| Cameron DR, et al.(2022) Parallel Evolution of Pseudomonas aeruginosa during a Prolonged ICU-Infection Outbreak.Microbiol Spectr Nov 7 doi: 10.1128/spectrum.02743-22. | 2022 | 微生物およびモデル生物 | |
| Martinez P, et al.(2022) Bassoon contributes to tau-seed propagation and neurotoxicity.Nat Neurosci Nov 7 doi: 10.1038/s41593-022-01191-6. | 2022 | 神経生物学 | |
| Li Z, et al.(2022) Xuanfei Baidu Formula alleviates impaired mitochondrial dynamics and activated NLRP3 inflammasome by repressing NF-κB and MAPK pathways in LPS-induced ALI and inflammation models.Phytomedicine Nov 9 doi: 10.1016/j.phymed.2022.154545. | 2022 | Mitochondrial studies | |
| Nanduri B, et al.(2023) Using Activity-Based Proteomics for the Quantification of Deubiquitinases in Animal Tissue.Methods Mol Biol 2591:45-57. | 2022 | メソッド開発 | |
| Wang J, et al.(2022) Nuclear paraspeckle assembly transcript 1 promotes the podocyte injury via targeting miR-23b-3p/B-cell lymphoma-2 interacting protein 3 like axis.Ren Fail 44(1):1961-1975. | 2022 | その他 | |
| Spetz JKE, et al.(2022) Heightened apoptotic priming of vascular cells across tissues and life span predisposes them to cancer therapy–induced toxicities.Sci Adv 8(45):eabn6579. | 2022 | がん研究 | 一般 |
| Hepowit NL, et al.(2023) Application of Archaea in Deubiquitinase-Like Enzyme Discovery and Activity Assay.Methods Mol Biol 2591:151-169. | 2022 | メソッド開発 | |
| Kim H, et al.(2022) Afrormosin exerts an anticancer effect via MAPK and AKT signaling pathways in B16F10 cells.Appl Biol Chem 65 71. | 2022 | がん研究 | 皮膚がん |
| Song J, et al.(2022) Matrix Adhesiveness Regulates Myofibroblast Differentiation from Vocal Fold Fibroblasts in a Bio-orthogonally Cross-linked Hydrogel.ACS Appl Mater Interfaces 14(46):51669-51682. | 2022 | その他 | |
| Xenias HS, et al.(2022) R1441C and G2019S LRRK2 knockin mice have distinct striatal molecular, physiological, and behavioral alterations.Commun Biol 5(1):1211. | 2022 | その他 | |
| Benoit M, et al.(2022) Postnatal neuronal Bace1 deletion impairs neuroblast and oligodendrocyte maturation.Hum Mol Genet Nov 12 doi: 10.1093/hmg/ddac282. | 2022 | その他 | |
| Joo S, et al.(2022) α-ketoglutarate suppresses immediate early gene expression in cancer cells.Biochem Biophys Res Commun 637:144-152. | 2022 | がん研究 | 一般 |
| Jacob C, et al.(2022) Mediterranean G6PD variant mitigates expression of DNA methyltransferases and right heart pressure in experimental model of pulmonary hypertension.J Biol Chem Nov 10 doi: 10.1016/j.jbc.2022.102691. | 2022 | その他 | |
| Liu Y, et al.(2022) Melatonin alleviates heat stress-induced testicular damage in dairy goats by inhibiting the PI3K/AKT signaling pathway.Stress Biology 2: 47. | 2022 | 細胞シグナル伝達 | |
| Liu X, et al.(2022) CD16+ fibroblasts foster a trastuzumab-refractory microenvironment that is reversed by VAV2 inhibition.Cancer Cell 40(11):1341-1357. | 2022 | がん研究 | 乳がん |
| Sridaran D, et al.(2022) Inhibiting ACK1-mediated phosphorylation of C-terminal Src kinase counteracts prostate cancer immune checkpoint blockade resistance.Nat Commun 13(1):6929. | 2022 | がん研究 | 一般 |
| Park SH, et al.(2022) Inositol polyphosphates‐regulated polyubiquitination of PHR1 by NLA E3 ligase during phosphate starvation response in Arabidopsis.New Phytol Nov 14 doi: 10.1111/nph.18621. | 2022 | 植物科学 | |
| Feng Y, et al.(2022) Promotion of osteogenesis in BMSC under hypoxia by ATF4 via the PERK–eIF2α signaling pathway.In Vitro Cell Dev Biol Anim Nov 15 doi: 10.1007/s11626-022-00732-4. | 2022 | 細胞シグナル伝達 | |
| Guidry G, et al.(2022) 17β-estradiol ameliorates delirium-like phenotypes in a murine model of urinary tract infection.Sci Rep 12(1):19622. | 2022 | 神経生物学 | |
| Xu M, et al.(2022) Alteration in tyrosine phosphorylation of cardiac proteome and EGFR pathway contribute to hypertrophic cardiomyopathy.Commun Biol 5(1):1251. | 2022 | 疾病研究 | バイオマーカー研究 |
| Shin E, et al.(2022) LDR-adapted liver-derived cytokines have potential to induce atherosclerosis.Int J Radiat Biol Nov 16 doi: 10.1080/09553002.2023.2145028. | 2022 | その他 | |
| Sheriff A, et al.(2022) ABE8e adenine base editor precisely and efficiently corrects a recurrent COL7A1 nonsense mutation.Sci Rep 12(1):19643. | 2022 | DNA修復プロセス | |
| Hong SC, et al.(2022) Protective effect of Tisochrysis lutea on dry eye syndrome via NF-κB inhibition.Sci Rep 12(1):19576. | 2022 | その他 | |
| Zhang N, et al.(2022) LCMT1 indicates poor prognosis and is essential for cell proliferation in hepatocellular carcinoma.Transl Oncol 27:101572. | 2022 | がん研究 | 肝臓がん |
| Wu HF, et al.(2022) Norepinephrine transporter defects lead to sympathetic hyperactivity in Familial Dysautonomia models.Nat Commun 13(1):7032. | 2022 | 神経生物学 | |
| Jamshidi-adegani F, et al.(2022) Comparative study of the cytotoxicity, apoptotic, and epigenetic effects of Boswellic acid derivatives on breast cancer.Sci Rep 12(1):19979. | 2022 | がん研究 | 乳がん |
| Wang HC, et al.(2022) Tumor-associated macrophages promote resistance of hepatocellular carcinoma cells against sorafenib by activating CXCR2 signaling.J Biomed Sci 29(1):99. | 2022 | がん研究 | 肝臓がん |
| Shin JY, et al.(2022) Priming mesenchymal stem cells with α-synuclein enhances neuroprotective properties through induction of autophagy in Parkinsonian models.Stem Cell Res Ther 13(1):483. | 2022 | 神経生物学 | |
| Li W, et al.(2022) BdcSP10 is a prophenoloxidase-activating protease in Bactrocera dorsalis.Dev Comp Immunol 138:104558. | 2022 | その他 | |
| Palmelund LB, et al.(2022) Development of a medium throughput whole-cell microtiter plate Thr286 autophosphorylation assay for CaMKIIα using ELISA.J Pharmacol Toxicol Methods 118:107226. | 2022 | メソッド開発 | |
| Menkhorst E, et al.(2022) Galectin-7 dysregulates renin-angiotensin-aldosterone and NADPH oxide synthase pathways in preeclampsia.Pregnancy Hypertens 30:130-136. | 2022 | 細胞シグナル伝達 | |
| Jovanović Stojanov S, et al.(2022) Autophagy Inhibition Enhances Anti-Glioblastoma Effects of Pyrazolo [3, 4-d] pyrimidine Tyrosine Kinase Inhibitors.Life 12(10):1503. | 2022 | がん研究 | 脳腫瘍 |
| Chan KL, et al.(2022) Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses.Cancer Cell Sep 19 doi: 10.1016/j.ccell.2022.09.007. | 2022 | がん研究 | 一般 |
| Jana A, et al.(2022) Increased Type I interferon signaling and brain endothelial barrier dysfunction in an experimental model of Alzheimer's disease.Sci Rep 12(1):16488. | 2022 | 神経生物学 | |
| Tatara M, et al.(2023) ATAC-Seq Analysis of Accessible Chromatin: From Experimental Steps to Data Analysis.Methods Mol Biol 2577:65-81. | 2022 | メソッド開発 | |
| Tran NL, et al.(2022) Facile Construction of Tumour Spheroids with Induced M2 Macrophage Polarization for Anticancer Drug Screening.Biomed Mater Sep 27 doi: 10.1088/1748-605X/ac956c. | 2022 | がん研究 | 一般 |
| Xiong X, et al.(2022) MicroRNA-34b-5p targets PPP1R11 to inhibit proliferation and promote apoptosis in cattleyak Sertoli cells by regulating specific signaling pathways.Theriogenology 194:46-57. | 2022 | 細胞シグナル伝達 | |
| Hsueh SC, et al.(2022) Activity of a Novel Anti-Inflammatory Agent F-3, 6′-dithiopomalidomide as a Treatment for Traumatic Brain Injury.Biomedicines 10(10):2449. | 2022 | 神経生物学 | |
| Qrareya AN, et al.(2022) HIV-1 Tat Upregulates the Receptor for Advanced Glycation End Products and Superoxide Dismutase-2 in the Heart of Transgenic Mice.Viruses 14(10):2191. | 2022 | その他 | |
| Chalise U, et al.(2022) Harnessing the Plasma Proteome to Mirror Current and Predict Future Cardiac Remodeling After Myocardial Infarction.J Cardiovasc Transl Res Oct 5 doi: 10.1007/s12265-022-10326-w. | 2022 | 疾病研究 | バイオマーカー研究 |
| Qin L, et al.(2022) The miR-21-5p enriched in the apoptotic bodies of M2 macrophage-derived extracellular vesicles alleviates osteoarthritis by inducing a change in the macrophage phenotype.Genes & Diseases Oct 5 doi: 10.1016/j.gendis.2022.09.010. | 2022 | その他 | |
| Pellavio G, et al.(2022) Aquaporin-6 May Increase the Resistance to Oxidative Stress of Malignant Pleural Mesothelioma Cells.Cells 11(12):1892. | 2022 | がん研究 | 肺がん |
| Tramonti A, et al.(2022) Characterization of the Escherichia coli pyridoxal 5'‐phosphate homeostasis protein (YggS): role of lysine residues in PLP binding and protein stability.Protein Sci Oct 11 doi: 10.1002/pro.4471. | 2022 | 構造生物学／タンパク質相互作用 | |
| El Hamdaoui Y, et al.(2022) Analysis of hyperforin (St. John's wort) action at TRPC6 channel leads to the development of a new class of antidepressant drugs.Mol Psychiatry Oct 12 doi: 10.1038/s41380-022-01804-3. | 2022 | 神経生物学 | |
| Durand-de Cuttoli R, et al.(2022) Distinct forms of regret linked to resilience versus susceptibility to stress are regulated by region-specific CREB function in mice.Sci Adv 8(42):eadd5579. | 2022 | 神経生物学 | |
| Mills C, et al.(2022) A Novel CRISPR Interference Effector Enabling Functional Gene Characterization with Synthetic Guide RNAs.CRISPR J Oct 17 doi: 10.1089/crispr.2022.0056. | 2022 | CRISPR | |
| Griem-Krey N, et al.(2022) The CaMKIIα hub ligand Ph-HTBA promotes neuroprotection after focal ischemic stroke by a distinct molecular interaction.Biomed Pharmacother 156:113895. | 2022 | 神経生物学 | |
| Sun H, et al.(2022) Increased circulating microparticles contribute to severe infection and adverse outcomes of COVID-19 patients with diabetes.Am J Physiol Heart Circ Physiol Oct 21 doi: 10.1152/ajpheart.00409.2022. | 2022 | その他 | |
| Choi W, et al.(2022) Targeted thrombolysis by magnetoacoustic particles in photothrombotic stroke model.Biomater Res 26(1):58. | 2022 | 薬剤機構 | |
| Lu X, et al.(2022) Silencing SNHG1 Suppresses Viability, Proliferation and Invasion of Gallbladder Carcinoma Cells via Targeting miR-194-5p.Ann Clin Lab Sci 52(5):707-720. | 2022 | がん研究 | 一般 |
| Li Z, et al.(2022) Enhancing Gasdermin-induced tumor pyroptosis through preventing ESCRT-dependent cell membrane repair augments antitumor immune response.Nat Commun 13(1):6321. | 2022 | がん研究 | 一般 |
| Park JS, et al.(2022) Isoform-specific inhibition of FGFR signaling achieved by a de-novo-designed mini-protein.Cell Rep 41(4):111545. | 2022 | 構造生物学／タンパク質相互作用 | |
| Zhou G, et al.(2022) Co-alterations of circadian clock gene transcripts in human placenta in preeclampsia.Sci Rep 12(1):17856. | 2022 | その他 | |
| Cruz JA, et al.(2022) A pseudovirus-based platform to measure neutralizing antibodies in Mexico using SARS-CoV-2 as proof-of-concept.Sci Rep 12(1):17966. | 2022 | メソッド開発 | |
| Bergman H, et al.(2022) Establishment of Cytotoxic and Non-cytotoxic NK-92 Cell Clones–Evaluation of Their Function as Target Cells.Anticancer Res 42(9):4259-4264. | 2022 | がん研究 | 一般 |
| Okada C, et al.(2022) Establishment of Neutralizing Monoclonal Antibodies Against Severe Acute Respiratory Syndrome Coronavirus 2 by the Screening with Exosomes Expressing the Viral Spike Protein.Monoclon Antib Immunodiagn Immunother (4):173-180. | 2022 | メソッド開発 | |
| Cui S, et al.(2022) SIRT1 activation synergizes with FXR agonism in hepatoprotection via governing nucleocytoplasmic shuttling and degradation of FXR.Acta Pharmaceutica Sinica B Aug 27 doi: 10.1016/j.apsb.2022.08.019. | 2022 | その他 | |
| Chen Y, et al.(2022) Tumour-associated Mucin1 correlates with the procoagulant properties of cancer cells of epithelial origin.Thrombosis Update 9: 100123. | 2022 | がん研究 | 一般 |
| Stenvall CGA, et al.(2022) Cytoplasmic keratins couple with and maintain nuclear envelope integrity in colonic epithelial cells.Mol Biol Cell Aug 24 doi: 10.1091/mbc.E20-06-0387. | 2022 | 構造生物学／タンパク質相互作用 | |
| Ju P, et al.(2022) Histone deacetylase 4 inhibition ameliorates the social deficits induced by Ephrin-B2 mutation.Prog Neuropsychopharmacol Biol Psychiatry Aug 24 doi: 10.1016/j.pnpbp.2022.110622. | 2022 | 神経生物学 | |
| Spampinato SF, et al.(2022) Microglia Contributes to BAF-312 Effects on Blood–Brain Barrier Stability.Biomolecules 12(9): 1174. | 2022 | 神経生物学 | |
| Pritchard Jr KA, et al.(2022) Role of endoplasmic reticulum stress in impaired neonatal lung growth and bronchopulmonary dysplasia.PLoS One 17(8):e0269564. | 2022 | その他 | |
| Zhang G, et al.(2022) ACOT7 protects epidermal stem cells against lipid peroxidation.In Vitro Cell Dev Biol Anim Aug 29 doi: 10.1007/s11626-022-00703-9. | 2022 | その他 | |
| Yin J, et al.(2022) Development of Whole-Cell Biosensors for Screening of Peptidoglycan-Targeting Antibiotics in a Gram-Negative Bacterium.Appl Environ Microbiol Aug 30 doi: 10.1128/aem.00846-22. | 2022 | メソッド開発 | |
| Han Z, et. al.(2022) Hsp20 Promotes Endothelial Progenitor Cell Angiogenesis via Activation of PI3K/Akt Signaling Pathway under Hypoxia.Tissue Eng Regen Med Aug 30 doi: 10.1007/s13770-022-00481-1. | 2022 | 細胞シグナル伝達 | |
| Basu S, et al.(2022) Negative Feedback Loop Mechanism between EAF1/2 and DBC1 in Regulating ELL Stability and Functions.Mol Cell Biol Aug 29 doi: 10.1128/mcb.00151-22. | 2022 | 構造生物学／タンパク質相互作用 | |
| López‐Haber C, et al.(2022) The phagosomal solute transporter SLC15A4 promotes inflammasome activity via mTORC1 signaling and autophagy restraint in dendritic cells.EMBO J Aug 29 doi: 10.15252/embj.2022111161. | 2022 | その他 | |
| Fowler EW, et al.(2022) A TGFβR inhibitor represses keratin-7 expression in 3D cultures of human salivary gland progenitor cells.Sci Rep 12(1):15008. | 2022 | 幹細胞 | |
| Kuppa S, et al.(2022) Rtt105 regulates RPA function by configurationally stapling the flexible domains.Nat Commun 13(1):5152. | 2022 | DNA修復プロセス | |
| Sawai M, et al.(2022) Dihydropyrazine suppresses TLR4-dependent inflammatory responses by blocking MAPK signaling in human hepatoma HepG2 cells.J Toxicol Sci 47(9):381-387. | 2022 | 細胞シグナル伝達 | |
| Jin N, et al.(2022) Tau seeding activity in various regions of down syndrome brain assessed by two novel assays.Acta Neuropathol Commun 10(1):132. | 2022 | 神経生物学 | |
| Shen H, et al.(2022) TRIM46 aggravated high glucose-induced hyper permeability and inflammatory response in human retinal capillary endothelial cells by promoting IκBα ubiquitination.Eye Vis (Lond) 9(1):35. | 2022 | その他 | |
| Gerhardy S, et al.(2022) Allosteric inhibition of HTRA1 activity by a conformational lock mechanism to treat age-related macular degeneration.Nat Commun 13(1):5222. | 2022 | 構造生物学／タンパク質相互作用 | |
| Tiwari R, et al.(2022) Chemical inhibition of oxygen-sensing prolyl hydroxylases impairs angiogenic competence of human vascular endothelium through metabolic reprogramming. iScience Sep 6 doi: 10.1016/j.isci.2022.105086. | 2022 | その他 | |
| Shi H, et al.(2022) Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer's-induced retinal vasculopathy by limiting Clec7a/Galectin-3+ neurodegenerative microglia.Acta Neuropathol Commun 10(1):136. | 2022 | 神経生物学 | |
| Visigalli R, et al.(2022) Expression and Function of ABC Transporters in Human Alveolar Epithelial Cells.Biomolecules 12(9):1260. | 2022 | その他 | |
| Schon SB, et al.(2022) Obesity-related alterations in protein expression in human follicular fluid from women undergoing in-vitro fertilization (IVF).F S Sci Sep 9 doi: 10.1016/j.xfss.2022.09.002. | 2022 | 疾病研究 | バイオマーカー研究 |
| Yoon JY, et al.(2022) Chemically-induced osteogenic cells for bone tissue engineering and disease modeling.Biomaterials 289:121792. | 2022 | メソッド開発 | |
| Jang M, et al.(2022) Hyperglycemic Neurovasculature‐On‐A‐Chip to Study the Effect of SIRT1‐Targeted Therapy for the Type 3 Diabetes “Alzheimer's Disease”.Adv Sci (Weinh) Sep 8 doi: 10.1002/advs.202201882. | 2022 | 神経生物学 | |
| Xue H, et al.(2022) A two-step mechanism governing PARP1-DNA retention by PARP inhibitors.Sci Adv 8(36):eabq0414. | 2022 | DNA修復プロセス | |
| Dai X, et al.(2022) KLF5-mediated aquaporin 3 activated autophagy to facilitate cisplatin resistance of gastric cancer.Immunopharmacol Immunotoxicol Sep 20 doi: 10.1080/08923973.2022.2122498. | 2022 | がん研究 | 胃がん |
| van Senten JR, et al.(2022) Use of CRISPR/Cas9-edited HEK293 cells reveals that both conventional and novel protein kinase C isozymes are involved in mGlu5a receptor internalization.J Biol Chem Sep 7 doi: 10.1016/j.jbc.2022.102466. | 2022 | CRISPR | |
| Mallard J, et al.(2022) Development of skeletal muscle atrophy and intermuscular adipose tissue in early breast cancer patients treated with chemotherapy.Am J Physiol Cell Physiol Sep 12 doi: 10.1152/ajpcell.00373.2022. | 2022 | がん研究 | 乳がん |
| Uquillas JA, et al.(2022) An off-the-shelf decellularized and sterilized human bone-ACL-bone allograft for anterior cruciate ligament reconstruction.J Mech Behav Biomed Mater 135:105452. | 2022 | その他 | |
| Song W and Qiu N (2022) MiR-495-3p depletion contributes to myocardial ischemia/reperfusion injury in cardiomyocytes by targeting TNC.Regen Ther 21: 380-388. | 2022 | その他 | |
| Kane EI, et al.(2022) Redefining the Catalytic HECT Domain Boundaries for the HECT E3 Ubiquitin Ligase Family.Biosci Rep Sep 16 doi: 10.1042/BSR20221036. | 2022 | 構造生物学／タンパク質相互作用 | |
| Zhang N, et al.(2022) Ameliorative effect of Lactobacillus plantarum Lp2 against cyclophosphamide-induced liver injury in mice.Food Chem Toxicol 169:113433. | 2022 | 細胞シグナル伝達 | |
| Wang S, et al.(2022) Ginseng polysaccharide attenuates red blood cells oxidative stress injury by regulating red blood cells glycolysis and liver gluconeogenesis.J Ethnopharmacol 300:115716. | 2022 | その他 | |
| Fonseca-Ornelas L, et al.(2022) Parkinson-causing mutations in LRRK2 impair the physiological tetramerization of endogenous α-synuclein in human neurons.NPJ Parkinsons Dis 8(1):118. | 2022 | 神経生物学 | |
| Barilli A, et al.(2022) The JAK1/2 Inhibitor Baricitinib Mitigates the Spike-Induced Inflammatory Response of Immune and Endothelial Cells In Vitro.Biomedicines 10(9):2324. | 2022 | 細胞シグナル伝達 | |
| Zhu X, et al.(2022) Structural basis of adhesion GPCR GPR110 activation by stalk peptide and G-proteins coupling.Nat Commun 13(1):5513. | 2022 | 構造生物学／タンパク質相互作用 | |
| Lim KM, et al.(2022) Advanced 3D Dynamic Culture System with Transforming Growth Factor-β3 Enhances Production of Potent Extracellular Vesicles with Modified Protein Cargoes via Upregulation of TGF-β Signaling.J Adv Res Sep 18 doi: 10.1016/j.jare.2022.09.005. | 2022 | メソッド開発 | |
| Huang Y, et al.(2022) Intracellular delivery of messenger RNA to macrophages with surfactant-derived lipid nanoparticles.Mater Today Adv 16: 100295. | 2022 | メソッド開発 | |
| Katifelis H, et al.(2022) Amniotic Fluid-Derived Mesenchymal Stem/Stromal Cell-Derived Secretome and Exosomes Improve Inflammation in Human Intestinal Subepithelial Myofibroblasts.Biomedicines 10(10): 2357. | 2022 | 幹細胞 | |
| Hauvermale AL, et al.(2022) GA signaling expands: the Plant UBX domain-containing protein 1 is a binding partner for the GA receptor.Plant Physiol Sep 23 doi: 10.1093/plphys/kiac406. | 2022 | 植物科学 | |
| Donne R, et al.(2022) Replication stress triggered by nucleotide pool imbalance drives DNA damage and cGAS-STING pathway activation in NAFLD.Dev Cell Jun 23 doi: 10.1016/j.devcel.2022.06.003. | 2022 | DNA修復プロセス | |
| Stewart JA, et al.(2022) A redox-sensitive iron-sulfur cluster in murine FAM72A controls its ability to degrade the nuclear form of uracil-DNA glycosylase.DNA Repair (Amst) 118:103381. | 2022 | DNA修復プロセス | |
| Watkins JM, et al.(2022) An Engineered Monovalent Anti–TNF-α Antibody with pH-Sensitive Binding Abrogates Immunogenicity in Mice following a Single Intravenous Dose.J Immunol Jul 27 doi: 10.4049/jimmunol.2101180. | 2022 | その他 | |
| Armstrong Z, et al.(2022) Cryo-EM structures of human fucosidase FucA1 reveal insight into substrate recognition and catalysis.Structure Jul 19 doi: 10.1016/j.str.2022.07.001. | 2022 | 構造生物学／タンパク質相互作用 | |
| Schlegel C, et al.(2022) Decreased expression of hypoxia-inducible factor 1α (HIF-1α) in cord blood monocytes under anoxia.Pediatr Res Jul 29 doi: 10.1038/s41390-022-02193-7. | 2022 | 細胞シグナル伝達 | |
| Crudele A, et al.(2022) Hydroxytyrosol Recovers SARS-CoV-2-PLpro-Dependent Impairment of Interferon Related Genes in Polarized Human Airway, Intestinal and Liver Epithelial Cells.Antioxidants 11(8):1466. | 2022 | その他 | |
| Fischer JA, et al.(2022) Opposing effects of genetic variation in MTCH2 for obesity versus heart failure.Hum Mol Genet Jul 29 doi: 10.1093/hmg/ddac176. | 2022 | 疾病研究 | バイオマーカー研究 |
| Hasegawa M, et al.(2022) Tumor suppressor effect of an antibody on xenotransplanted sarcomatoid mesothelioma cells.Thorac Cancer Aug 2 doi: 10.1111/1759-7714.14591. | 2022 | がん研究 | 一般 |
| Wang S, et al.(2022) Huanglian ointment alleviates eczema by maintaining the balance of c-Jun and JunB and inhibiting AGE-RAGE-mediated pro-inflammation signaling pathway.Phytomedicine 105:154372. | 2022 | 細胞シグナル伝達 | |
| Zhi Y, et al.(2022) The effects of air pollutants exposure on the transmission and severity of invasive infection caused by an opportunistic pathogen Streptococcus pyogenes.Environ Pollut Aug 3 doi: 10.1016/j.envpol.2022.119826. | 2022 | 微生物およびモデル生物 | |
| Kolhe P, et al.(2022) Fabrication of an ultrasensitive electrochemical immunosensor coupled with biofunctionalized zero-dimensional graphene quantum dots for rapid detection of cephalexin.Food Chemistry 398:133846. | 2022 | メソッド開発 | |
| Nelczyk AT, et al.(2022) The nuclear receptor TLX (NR2E1) inhibits growth and progression of triple-negative breast cancer.Biochim Biophys Acta Mol Basis Dis Aug 3 doi: 10.1016/j.bbadis.2022.166515. | 2022 | がん研究 | 乳がん |
| Leng F, et al.(2022) The transcription factor FoxP3 can fold into two dimerization states with divergent implications for regulatory T cell function and immune homeostasis.Immunity 55(8):1354-1369.e8. | 2022 | 構造生物学／タンパク質相互作用 | |
| Eccardt AM, et al.(2022) Stimulation of Akt Phosphorylation and Glucose Transport by Metalloporphyrins with Peroxynitrite Decomposition Catalytic Activity.Catalysts 12(8):849. | 2022 | 細胞シグナル伝達 | |
| El-Sayed D, et al.(2022) Evaluating the Phenotypic and Genomic Characterization of Some Egyptian Phages Infecting Shiga Toxin-Producing Escherichia coli O157: H7 for the Prospective Application in Food Bio-Preservation.Biology 11(8)1180. | 2022 | 微生物およびモデル生物 | |
| Costa TC, et al.(2022) Ruminal undegradable protein enriched diet during late gestation of beef cows affects maternal metabolism and offspring's skeletal muscle development.Anim Feed Sci Technol 291:115400. | 2022 | その他 | |
| Metformin improves depressive-like behavior in experimental Parkinson's disease by inducing autophagy in the substantia nigra and hippocampus.Inflammopharmacology Aug 6 doi: 10.1007/s10787-022-01043-6. | 2022 | 神経生物学 | |
| Sherlock D. and Fogg PCM.(2022) The archetypal gene transfer agent RcGTA is regulated via direct interaction with the enigmatic RNA polymerase omega subunit.Cell Rep 40(6):111183. | 2022 | その他 | |
| Desjardins CA, et al.(2022) Enhanced exon skipping and prolonged dystrophin restoration achieved by TfR1-targeted delivery of antisense oligonucleotide using FORCE conjugation in mdx mice.Nucleic Acids Res Aug 10 doi: 10.1093/nar/gkac641. | 2022 | 神経生物学 | |
| Emdal KB, et al.(2022) Phosphoproteomics of primary AML patient samples reveals rationale for AKT combination therapy and p53 context to overcome selinexor resistance.Cell Rep 40(6):111177. | 2022 | 神経生物学 | |
| Dupont V, et al.(2022) Impaired renal reserve contributes to preeclampsia via the kynurenine and soluble fms-like tyrosine kinase 1 pathway.J Clin Invest Aug 9 doi: 10.1172/JCI158346. | 2022 | 細胞シグナル伝達 | |
| Guo X, et al.(2022) Vasorin contributes to lung injury via FABP4-mediated inflammation.Mol Biol Rep Aug 10 doi: 10.1007/s11033-022-07780-9. | 2022 | その他 | |
| Lopes FBTP, et al.(2022) Temporal and sex-linked protein expression dynamics in a familial model of Alzheimer's Disease.Mol Cell Proteomics Aug 6 doi: 10.1016/j.mcpro.2022.100280. | 2022 | 神経生物学 | |
| Gatticchi L, et al.(2022) CRISPR/Cas9-mediated knock-out of AGXT1 in HepG2 cells as a new in vitro model of Primary Hyperoxaluria Type 1.Biochimie Aug 11 doi: 10.1016/j.biochi.2022.08.005. | 2022 | CRISPR | |
| Lazcano P, et al.(2022) Phosphatidic acid inhibits inositol synthesis by inducing nuclear translocation of kinase IP6K1 and repression of myo-inositol-3-P synthase.J Biol Chem Aug 10 doi: 10.1016/j.jbc.2022.102363. | 2022 | 細胞シグナル伝達 | |
| D'Acunzo P, et al.(2022) Isolation of mitochondria-derived mitovesicles and subpopulations of microvesicles and exosomes from brain tissues.Nat Protoc Aug 12. doi: 10.1038/s41596-022-00719-1. | 2022 | メソッド開発 | |
| H Fu, et al.(2023) The heated-induced gelation of soy protein isolate at subunit level: Exploring the impacts of α and α′ subunits on SPI gelation based on natural hybrid breeding varieties.Food Hydrocolloids doi: 10.1016/j.foodhyd.2022.108008. | 2022 | 植物科学 | |
| Xu Q, et al.(2022) CircSERPINA3 promoted cell proliferation, migration, and invasion of laryngeal squamous cell carcinoma by targeting miR‐885‐5p.Cell Biol Int Aug 16 doi: 10.1002/cbin.11872. | 2022 | がん研究 | 扁平上皮がん |
| Tachibana N, et al.(2022) RSPO2 defines a distinct undifferentiated progenitor in the tendon/ligament and suppresses ectopic ossification.Sci Adv 8(33):eabn2138. | 2022 | その他 | |
| Kushwaha A, et al.(2022) Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxododecanoyl) homoserine lactone induces calcium signaling-dependent crosstalk between autophagy and apoptosis in human macrophages.Cell Signal 99:110441. | 2022 | 細胞シグナル伝達 | |
| Zafferani M, et al.(2022) Multiassay Profiling of a Focused Small Molecule Library Reveals Predictive Bidirectional Modulation of the lncRNA MALAT1 Triplex Stability In Vitro.ACS Chem Biol Aug 19 doi: 10.1021/acschembio.2c00124. | 2022 | メソッド開発 | |
| Pozzi S, et al.(2022) MCP-1/CCR2 axis inhibition sensitizes the brain microenvironment against melanoma brain metastasis progression.JCI Insight Aug 18 doi: 10.1172/jci.insight.154804. | 2022 | がん研究 | 脳腫瘍 |
| Jia H, et al.(2022) Highly efficient and simple SSPER and rrPCR approaches for the accurate site-directed mutagenesis of large and small plasmids.N Biotechnol Aug 22 doi: 10.1016/j.nbt.2022.08.004. | 2022 | メソッド開発 | |
| Mukherjee D, et al.(2022) Fetal pulmonary hypertension: dysregulated microRNA-34c-Notch1 axis contributes to impaired angiogenesis in an ovine model.Pediatr Res Jun 18 doi: 10.1038/s41390-022-02151-3. | 2022 | その他 | |
| Zhang D, et al.(2022) Upregulation of miR‐144‐3p alleviates Doxorubicin‐induced heart failure and cardiomyocytes apoptosis via SOCS2/PI3K/AKT axis.Chem Biol Drug Des Jun 22. doi: 10.1111/cbdd.14104. | 2022 | 細胞シグナル伝達 | |
| He J, et al.(2022) Ruscogenin Ameliorated Sjögren's Syndrome by Inhibiting NLRP3 Inflammasome Activation.Evid Based Complement Alternat Med Jun 28 doi: 10.1155/2022/6425121. | 2022 | 細胞シグナル伝達 | |
| Fang CL, et al.(2022) Angelica dahurica attenuates melanogenesis in B16F0 cells by repressing Wnt/β-catenin signaling.Mol.Cell.Toxicol June 27 doi: 10.1007/s13273-022-00250-0. | 2022 | その他 | |
| Mohamed ISE, et al.(2022) Bovine Pancreatic RNase A: An Insight into the Mechanism of Antitumor Activity In Vitro and In Vivo.Pharmaceutics 14(6):1173. | 2022 | がん研究 | 皮膚がん |
| Lee EH, et al.(2022) Inhibition of TRPM7 suppresses migration and invasion of prostate cancer cells via inactivation of ERK1/2, Src and Akt pathway signaling.J. Mens Health 18(7):144. | 2022 | がん研究 | 一般 |
| Kim JH, et al.(2022) Increasing the resilience of plant immunity to a warming climate.Nature Jun 29 doi: 10.1038/s41586-022-04902-y. | 2022 | 植物科学 | |
| Marcovich I, et al.(2033) Optimized AAV Vectors for TMC1 Gene Therapy in a Humanized Mouse Model of DFNB7/11.Biomolecules 12(7): 914. | 2022 | メソッド開発 | |
| Porcù E, et al.(2022) Identification of Homoharringtonine as a potent inhibitor of glioblastoma cell proliferation and migration.Transl Res Jul 1 doi: 10.1016/j.trsl.2022.06.017. | 2022 | がん研究 | 脳腫瘍 |
| Park SK, et al.(2022) Porphyra tenera Protects against PM2.5-Induced Cognitive Dysfunction with the Regulation of Gut Function.Mar. Drugs 20(7):439. | 2022 | 神経生物学 | |
| Avila H, et al.(2022) Hydra-Elastin-like Polypeptides Increase Rapamycin Potency When Targeting Cell Surface GRP78.Biomacromolecules Jul 5 doi: 10.1021/acs.biomac.2c00048. | 2022 | 薬剤機構 | |
| Han SM, et al.(2022) The Change in Circadian Rhythms in P301S Transgenic Mice is Linked to Variability in Hsp70-related Tau Disaggregation.Exp Neurobiol 31(3):196-207. | 2022 | 神経生物学 | |
| Li Z, et al.(2022) Sodium para-aminosalicylic acid ameliorates lead-induced hippocampal neuronal apoptosis by suppressing the activation of the IP3R-Ca2+-ASK1-p38 signaling pathway.Ecotoxicol Environ Saf 241:113829. | 2022 | 神経生物学 | |
| Pemberton K, et al.(2022) Differential Effects of the G Protein-Coupled Estrogen Receptor (GPER) on Rat Embryonic (E18) Hippocampal and Cortical Neurons. eNeuro Jun 30 doi: 10.1523/ENEURO.0475-21.2022. | 2022 | 神経生物学 | |
| Poli E, et al.(2022) Immunoreactivity against fibroblast growth factor 8 in alveolar rhabdomyosarcoma patients and its involvement in tumor aggressiveness.Oncoimmunology 11(1):2096349. | 2022 | がん研究 | 一般 |
| Baglyas M, et al.(2022) High-performance thin-layer chromatography-antibacterial assay first reveals bioactive clerodane diterpenes in giant goldenrod (Solidago gigantea Ait.).J Chromatogr A July 9 doi: 10.1016/j.chroma.2022.463308. | 2022 | 植物科学 | |
| Chu HS, et al.(2022) Integrated Stress Response Regulation of Corneal Epithelial Cell Motility and Cytokine Production.Invest Ophthalmol Vis Sci 63(8):1. | 2022 | 細胞シグナル伝達 | |
| Swain RM, et al.(2022) Two novel piperidones induce apoptosis and antiproliferative effects on human prostate and lymphoma cancer cell lines.Invest New Drugs Jul 6 doi: 10.1007/s10637-022-01266-y. | 2022 | がん研究 | 一般 |
| Wu LK, et al.(2022) Artemisia Leaf Extract protects against neuron toxicity by TRPML1 activation and promoting autophagy/mitophagy clearance in both in vitro and in vivo models of MPP+ and MPTP induced Parkinson’s disease.Phytomedicine 104:154250. | 2022 | 神経生物学 | |
| Shahdeo D, et al.(2022) Graphene-Based Field-Effect Transistor for Ultrasensitive Immunosensing of SARS-CoV-2 Spike S1 Antigen.ACS Appl Bio Mater 5(7):3563-3572. | 2022 | メソッド開発 | |
| Duschmalé J, et al.(2022) Investigating discovery strategies and pharmacological properties of stereodefined phosphorodithioate LNA gapmers.Mol Ther Nucleic Acids 29:176-188. | 2022 | メソッド開発 | |
| Hu F, et al.(2022) Bioinformatics analysis of KLF2 as a potential prognostic factor in ccRCC and association with epithelial‑mesenchymal transition.Exp Ther Med 24:561. | 2022 | がん研究 | 一般 |
| Halle JL, et al.(2022) Short duration treadmill exercise improves physical function and skeletal muscle mitochondria protein expression after recovery from FOLFOX chemotherapy in male mice.FASEB J 36(8):e22437. | 2022 | Mitochondrial studies | |
| Weinheimer AS, et al.(2022) Extended DNA binding interfaces beyond the canonical SAP domain contribute to the function of replication stress regulator SDE2 at DNA replication forks.J Biol Chem Jul 15 doi: 10.1016/j.jbc.2022.102268. | 2022 | DNA修復プロセス | |
| Guleria VS, et al.(2022) The intraflagellar transport protein IFT52 associated with short-rib thoracic dysplasia is essential for ciliary function in osteogenic differentiation in vitro and for sensory perception in Drosophila.Exp Cell Res 418(2):113273. | 2022 | 神経生物学 | |
| Qin W, et al.(2022) Osteoglycin (OGN) promotes tumorigenesis of pancreatic cancer cell via targeting ID4.Tissue and Cell July 16 doi: 10.1016/j.tice.2022.101867. | 2022 | がん研究 | 膵臓がん |
| Ye Z, et al.(2022) LMCD1 facilitates the induction of pluripotency via cell proliferation, metabolism, and epithelial‐mesenchymal transition.Cell Biol Int Jul 16 doi: 10.1002/cbin.11858. | 2022 | その他 | |
| Demonbreun AR, et al.(2022) A conserved annexin A6–mediated membrane repair mechanism in muscle, heart, and nerve.JCI Insight 7(14):e158107. | 2022 | 神経生物学 | |
| Singh N, et al.(2022) Targeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance.Sci Adv 8(29):eabo3610. | 2022 | 神経生物学 | |
| Wang Z, et al.(2022) The N6-methyladenosine writer WTAP contributes to the induction of immune tolerance post kidney transplantation by targeting regulatory T cells.Lab Invest Jul 21 doi: 10.1038/s41374-022-00811-w. | 2022 | その他 | |
| Simeone CA, et al.(2022) A dominant negative ADIPOQ mutation in a diabetic family with renal disease, hypoadiponectinemia, and hyperceramidemia.NPJ Genom Med 7(1):43. | 2022 | 疾病研究 | バイオマーカー研究 |
| Dong ZB, et al.(2022) Resveratrol ameliorates oxaliplatin‑induced neuropathic pain via anti‑inflammatory effects in rats.Exp Ther Med July 21 doi: 10.3892/etm.2022.11523. | 2022 | 神経生物学 | |
| Zhang L, et al.(2022) Measuring Cytological Proximity of Chromosomal Loci to Defined Nuclear Compartments with TSA-seq. Methods Mol Biol 2532:145-186. | 2022 | メソッド開発 | |
| Song D, et al.(2022) Dual-hairpin ligation amplification enabled ultra-sensitive and selective ATP detection for cancer monitor.Biosens Bioelectron 212:114402. | 2022 | その他 | |
| John L, et al.(2022) Redirecting Imipramine against Bluetongue Virus Infection: Insights from a Genome-wide Haploid Screening Study.Pathogens 11(5):602. | 2022 | その他 | |
| Du Q, et al.(2022) Bioinformatics analysis of LMAN1 expression, clinical characteristics, and its effects on cell proliferation and invasion in glioma.Brain Res 1789:147952. | 2022 | がん研究 | 脳腫瘍 |
| Grismaldo Rodríguez A, et al.(2022) Effect of Platelet-Derived Growth Factor C on Mitochondrial Oxidative Stress Induced by High d-Glucose in Human Aortic Endothelial Cells.Pharmaceuticals (Basel) 15(5):639. | 2022 | 細胞シグナル伝達 | |
| Simões V, et al.(2022) Redox-sensitive E2 Rad6 controls cellular response to oxidative stress via K63-linked ubiquitination of ribosomes.Cell Rep 39(8):110860. | 2022 | その他 | |
| Altegoer F, et al.(2022) Structural insights into the mechanism of archaellar rotational switching.Nat Commun 13(1):2857. | 2022 | 構造生物学／タンパク質相互作用 | |
| Gangopadhyay A, et al.(2022) NLRP3 licenses NLRP11 for inflammasome activation in human macrophages.Nat Immunol 23(6):892-903. | 2022 | 細胞シグナル伝達 | |
| Roy S, et al.(2022) Role of MrgprB2 in Rosacea-like Inflammation in Mice: Modulation by βarrestin2.J Invest Dermatol May 26 doi: 10.1016/j.jid.2022.05.005. | 2022 | 細胞シグナル伝達 | |
| Matyushkina D, et al.(2022) Autoimmune Effect of Antibodies against the SARS-CoV-2 Nucleoprotein.Viruses 14(6): 1141. | 2022 | 微生物およびモデル生物 | |
| Zhang Q, et al.(2022) Down-Regulating Scar Formation by Microneedles Directly via a Mechanical Communication Pathway.ACS Nano May 26 doi: 10.1021/acsnano.1c11016. | 2022 | メソッド開発 | |
| Lin S, et al.(2022) TGF-β1 regulates chondrocyte proliferation and extracellular matrix synthesis via circPhf21a-Vegfa axis in osteoarthritis.Cell Commun Signal 20(1):75. | 2022 | 細胞シグナル伝達 | |
| Fan X, et al.(2022) Iron-Regulated Assembly of the Cytosolic Iron-Sulfur Cluster Biogenesis Machinery.J Biol Chem May 30 doi: 10.1016/j.jbc.2022.102094. | 2022 | 構造生物学／タンパク質相互作用 | |
| Shin CH, et al.(2022) Cytosolic microRNA-inducible nuclear translocation of Cas9 protein for disease-specific genome modification.Nucleic Acids Res 50(10):5919-5933. | 2022 | CRISPR | |
| Mohamed ISE, et al.(2022) Bovine Pancreatic RNase A: An Insight into the Mechanism of Antitumor Activity In Vitro and In Vivo.Pharmaceutics 14:1173. | 2022 | がん研究 | 一般 |
| Onori ME, et al.(2022) Genetics and Sport Injuries: New Perspectives for Athletic Excellence in an Italian Court of Rugby Union Players.Genes 13(6):995. | 2022 | その他 | |
| Jiang L, et al.(2022) Salidroside attenuates sepsis-associated acute lung injury through PPP1R15A mediated endoplasmic reticulum stress inhibition.Bioorg Med Chem June 1 doi: 10.1016/j.bmc.2022.116865. | 2022 | その他 | |
| Chalise U, et al.(2022) MMP-12 polarizes the neutrophil signalome towards an apoptotic signature.J Proteomics Jun 1 doi: 10.1016/j.jprot.2022.104636. | 2022 | 細胞シグナル伝達 | |
| Siddoway AC, et al.(2022) Structural Stability and Antigenicity of Universal Equine H3N8 Hemagglutinin Trimer upon Release from Polyanhydride Nanoparticles and Pentablock Copolymer Hydrogels.ACS Biomater Sci Eng May 23 doi: 10.1021/acsbiomaterials.2c00219. | 2022 | その他 | |
| Yang HY, et al.(2022) Glycogen synthase kinase‐3β inhibition decreases inflammation and relieves cancer induced bone pain via reducing Drp1‐mediated mitochondrial damage.J Cell Mol Med Jun 10 doi: 10.1111/jcmm.17432. | 2022 | がん研究 | 一般 |
| Csizmarik A, et al.(2022) Proteome profiling of enzalutamide‐resistant cell lines and serum analysis identified ALCAM as marker of resistance in castration‐resistant prostate cancer.Int J Cancer Jun 11 doi: 10.1002/ijc.34159. | 2022 | がん研究 | 一般 |
| Hallacli E, et al.(2022) The Parkinson's disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability.Cell 185(12):2035-2056.e33. | 2022 | 神経生物学 | |
| Vasquez I, et al.(2022) Comparative Genomics of Typical and Atypical Aeromonas salmonicida Complete Genomes Revealed New Insights into Pathogenesis Evolution.Microorganisms 10(1):189. | 2022 | 微生物およびモデル生物 | |
| Kim S, et al.(2022) Phosphorylation of GluA1-Ser831 by CaMKII activation in the caudate and putamen is required for behavioral sensitization after challenge nicotine in rats.Int J Neuropsychopharmacol Jun 9 doi: 10.1093/ijnp/pyac034. | 2022 | 神経生物学 | |
| Yang J, et al.(2022) Mmu_circ_0000271 regulated the growth of ox-LDL-stimulated mouse vascular smooth muscle cells via sponging miR-5123.Genes Genomics Jun 6 doi: 10.1007/s13258-022-01268-3. | 2022 | その他 | |
| Peng Y, et al.(2022) The Drosophila hnRNP F/H homolog Glorund recruits dFMRP to inhibit nanos translation elongation.Nucleic Acids Res Jun 14 doi: 10.1093/nar/gkac500. | 2022 | その他 | |
| Chen N, et al.(2022) YAP1 maintains active chromatin state in head and neck squamous cell carcinomas that promotes tumorigenesis through cooperation with BRD4.Cell Rep 39(11):110970. | 2022 | がん研究 | 扁平上皮がん |
| Guilloteau E, et al.(2022) Murine in utero exposure to simulated complex urban air pollution disturbs offspring gut maturation and microbiota during intestinal suckling-to-weaning transition in a sex-dependent manner.Part Fibre Toxicol 19(1):41. | 2022 | その他 | |
| Li W, et al.(2022) The downregulation of miR‐22 and miR‐372 may contribute to gestational diabetes mellitus through regulating glucose metabolism via the PI3K/AKT/GLUT4 pathway.J Clin Lab Anal Jun 17 doi: 10.1002/jcla.24557 | 2022 | 細胞シグナル伝達 | |
| Liu D, et al.(2022) Impact of schizophrenia GWAS loci converge onto distinct pathways in cortical interneurons vs glutamatergic neurons during development.Mol Psychiatry Jun 14 doi: 10.1038/s41380-022-01654-z. | 2022 | 神経生物学 | |
| Suthon S, et al.(2022) GATA4 and estrogen receptor alpha bind at SNPs rs9921222 and rs10794639 to regulate AXIN1 expression in osteoblasts Hum Genet Jun 9 doi: 10.1007/s00439-022-02463-8. | 2022 | 疾病研究 | バイオマーカー研究 |
| Giuliani E, et al.(2022) Obesity-induced follicular phase endometrial proteome dysregulation in a well-phenotyped population.F S Sci Jun 13 doi: 10.1016/j.xfss.2022.06.002. | 2022 | その他 | |
| Lee BR, et al.(2022) Ascorbate peroxidase‐mediated in situ labelling of proteins in secreted exosomes.J Extracell Vesicles 11(6):e12239. | 2022 | メソッド開発 | |
| Singh N, et al.(2022) BACE-1 inhibition facilitates the transition from homeostatic microglia to DAM-1.Sci Adv 8(24):eabo1286. | 2022 | その他 | |
| Garcia-Gerique L, et al.(2022) MIF/CXCR4 signaling axis contributes to survival, invasion, and drug resistance of metastatic neuroblastoma cells in the bone marrow microenvironment.BMC Cancer 22(1):669. | 2022 | がん研究 | 一般 |
| Jiang N, et al.(2022) Inhibition of Cpt1a alleviates oxidative stress-induced chondrocyte senescence via regulating mitochondrial dysfunction and activating mitophagy.Mech Ageing Dev 205:111688. | 2022 | がん研究 | 一般 |
| Haworth AS, et al.(2022) Subcellular dynamics and functional activity of the cleaved intracellular domain of the Na+ channel β1 subunit.J Biol Chem Jun 22 doi: 10.1016/j.jbc.2022.102174. | 2022 | がん研究 | 乳がん |
| Figueiredo J, et al.(2022) Encapsulation of the septal cell wall protects Streptococcus pneumoniae from its major peptidoglycan hydrolase and host defenses.PLoS Pathog 18(6):e1010516. | 2022 | 微生物およびモデル生物 | |
| Yang YY, et al.(2022) Moderate Dose Irradiation Induces DNA Damage and Impairments of Barrier and Host Defense in Nasal Epithelial Cells in vitro.J Inflamm Res 2022(15):3661—3675. | 2022 | DNA修復プロセス | |
| Othmène YB, et al.(2022) Triazole fungicide tebuconazole induces apoptosis through ROS-mediated endoplasmic reticulum stress pathway.Environ Toxicol Pharmacol Jun 23 doi: 10.1016/j.etap.2022.103919. | 2022 | 細胞シグナル伝達 | |
| TJ Yang TJ, et al.(2022) Tumor suppressor BAP1 nuclear import is governed by transportin-1.J Cell Biol 221(6):e202201094. | 2022 | がん研究 | 一般 |
| Sahu BP, et al.(2022) Genome-wide identification and characterization of microsatellite markers within the Avipoxviruses.3 Biotech 12(5):113. | 2022 | 疾病研究 | バイオマーカー研究 |
| West PK, et al.(2022) The cytokines interleukin-6 and interferon-α induce distinct microglia phenotypes.J Neuroinflammation 19(1):96. | 2022 | 神経生物学 | |
| M Diefenbacher M, et al.(2022) Interactions between Influenza A Virus Nucleoprotein and Gene Segment Untranslated Regions Facilitate Selective Modulation of Viral Gene Expression.J Virol Apr 25 doi: 10.1128/jvi.00205-22. | 2022 | 微生物およびモデル生物 | |
| Xu WF, et al.(2022) Octreotide-based therapies effectively protect mice from acute and chronic gastritis.Eur J Pharmacol Apr 26 doi: 10.1016/j.ejphar.2022.174976. | 2022 | 薬剤機構 | |
| Menna M, et al.(2022) Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models.Eur J Med Chem 237:114410. | 2022 | がん研究 | 一般 |
| Liu Y, et al.(2022) Whole-Exome Sequencing of Germline Variants in Non-BRCA Families with Hereditary Breast Cancer.Biomedicines 10(5):1004. | 2022 | がん研究 | 乳がん |
| Esfahani SA, et al.(2022) Hyperpolarized [1-13C] Pyruvate Magnetic Resonance Spectroscopic Imaging for Evaluation of Early Response to Tyrosine Kinase Inhibition Therapy in Gastric Cancer.Mol Imaging Biol Apr 25 doi: 10.1007/s11307-022-01727-z. | 2022 | がん研究 | 胃がん |
| Thompson L, et al.(2022) An eIF3d-dependent switch regulates HCMV replication by remodeling the infected cell translation landscape to mimic chronic ER stress.Cell Rep 39(5):110767. | 2022 | その他 | |
| Xue JB, et al.(2022) Heart failure in mice induces a dysfunction of the sinus node associated with reduced CaMKII signaling.J Gen Physiol 154(9):e202112895. | 2022 | 細胞シグナル伝達 | |
| Yang X, et al.(2022) MARCH8 attenuates cGAS-mediated innate immune responses through ubiquitylation.Sci Signal 15(732):eabk3067. | 2022 | その他 | |
| Butta GM, et al.(2022) Heterogeneity of Latency Establishment in the Different Human CD4+ T Cell Subsets Stimulated with IL-15.J Virol May 2 doi: 10.1128/jvi.00379-22. | 2022 | 微生物およびモデル生物 | |
| Siddiqui SH, et al.(2022) Modulatory effects of cell–cell interactions between porcine skeletal muscle satellite cells and fibroblasts on the expression of myogenesis-related genes.Journal of Applied Animal Research 50(1):259-268. | 2022 | その他 | |
| Yin W, Qian S. (2022) Delivery of cisplatin and resiquimod in nanomicelles for the chemoimmunotherapy of ovarian cancer.Cancer Nano 13:8 | 2022 | がん研究 | 卵巣がん |
| Qiao J, et al.(2022) Neuroprotective effect of Ginsenoside Re against neurotoxin‑induced Parkinson's disease models via induction of Nrf2.Mol Med Rep 25(6):215. | 2022 | 神経生物学 | |
| Dong C, et al.(2022) A genome-wide CRISPR-Cas9 knockout screen identifies essential and growth-restricting genes in human trophoblast stem cells.Nat Commun 13(1):2548. | 2022 | CRISPR | |
| Mahari S, et al.(2022) Probe-Free Nanosensor for the Detection of Salmonella Using Gold Nanorods as an Electroactive Modulator.Food Chem 390:133219. | 2022 | メソッド開発 | |
| Mohammed HHH, et al.(2022) New 1, 2, 3-triazole linked ciprofloxacin-chalcones induce DNA damage by inhibiting human topoisomerase I& II and tubulin polymerization.J Enzyme Inhib Med Chem 37(1):1346-1363. | 2022 | がん研究 | 一般 |
| Kshirsagar PG, et al.(2022) DNA-gold nanoprobe-based integrated biosensing technology for non-invasive liquid biopsy of serum miRNA: A new frontier in prostate cancer diagnosis.Nanomedicine May 12 doi: 10.1016/j.nano.2022.102566. | 2022 | がん研究 | 一般 |
| Harbuzariu A, et al.(2022) Neuregulin-1/ErbB4 signaling modulate Plasmodium falciparum HRP2-induced damage to brain cortical organoids.ISCIENCE May 14 doi: https://doi.org/10.1016/j.isci.2022.104407. | 2022 | 神経生物学 | |
| Jain RG, et al.(2022) Foliar application of clay-delivered RNA interference for whitefly control.Nat Plants 8(5):535-548. | 2022 | 植物科学 | |
| Taniguchi H, et al.(2022) WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC.Cell Rep 39(7):110814. | 2022 | がん研究 | 肺がん |
| Lu Y, et al.(2022) Patchouli alcohol protects against myocardial ischaemia–reperfusion injury by regulating the Notch1/Hes1 pathway.Pharm Biol 60(1):949-957. | 2022 | 細胞シグナル伝達 | |
| Shahdeo D, et al.(2022) Label free detection of SARS CoV-2 Receptor Binding Domain (RBD) protein by fabrication of gold nanorods deposited on electrochemical immunosensor (GDEI).Biosens Bioelectron 212:114406. | 2022 | メソッド開発 | |
| Rouault AAJ, et al.(2022) MRAP2 inhibits β-arrestin recruitment to the ghrelin receptor by preventing GHSR1a phosphorylation.J Biol Chem May 20 doi: 10.1016/j.jbc.2022.102057. | 2022 | 細胞シグナル伝達 | |
| Parashar D, et al.(2022) Patient-Derived Ovarian Cancer Spheroids Rely on PI3K-AKT Signaling Addiction for Cancer Stemness and Chemoresistance.Cancers (Basel) 14(4):958. | 2022 | がん研究 | 卵巣がん |
| Ni C, et al.(2022) Labeling of heterochronic ribosomes reveals C1ORF109 and SPATA5 control a late step in human ribosome assembly.Cell Rep 38(13):110597. | 2022 | その他 | |
| Niemeyer CS, et al.(2022) VZV Infection of Primary Human Adrenal Cortical Cells Produces a Proinflammatory Environment without Cell Death.Viruses 14(4):674. | 2022 | その他 | |
| Leo IR, et al.(2022) Integrative multi-omics and drug response profiling of childhood acute lymphoblastic leukemia cell lines.Nat Commun 13(1):1691. | 2022 | がん研究 | 血液がん |
| Donko A, et al.(2022) Interpretation of Dihydrorhodamine-1, 2, 3 Flow Cytometry in Chronic Granulomatous Disease: an Atypical Exemplar.J Clin Immunol Mar 28 doi: 10.1007/s10875-022-01217-5. | 2022 | その他 | |
| Jamieson F, et al.(2022) Ethylene signaling modulates Arabidopsis thaliana nitrate metabolism.Planta 255(5):94. | 2022 | 植物科学 | |
| Lee HK, et al.(2022) Sinkihwan-gamibang ameliorates puromycin aminonucleoside-induced nephrotic syndrome.Chin J Nat Med 20(3):177-184. | 2022 | その他 | |
| Gomes C, et al.(2022) Neurotoxic Astrocytes Directly Converted from Sporadic and Familial ALS Patient Fibroblasts Reveal Signature Diversities and miR-146a Theragnostic Potential in Specific Subtypes.Cells 11(7):1186. | 2022 | 神経生物学 | |
| Suzuki Y, et al.(2022) Rhodococcus equi U19 strain harbors a nonmobilizable virulence plasmid.Microbiol Immunol Mar 11 doi: 10.1111/1348-0421.12975. | 2022 | 微生物およびモデル生物 | |
| Cilibrasi V, et al.(2022) Synthesis of 2H-Imidazo [2′, 1': 2, 3][,] thiazolo [4, 5-e] isoindol-8-yl-phenylureas with promising therapeutic features for the treatment of acute myeloid leukemia (AML) with FLT3/ITD mutations | 2022 | がん研究 | 一般 |
| Ghaleb Y, et al.(2022) Whole Exome/Genome Sequencing Joint Analysis of a Family with Oligogenic Familial Hypercholesterolemia.Metabolites 12(3):262. | 2022 | 疾病研究 | バイオマーカー研究 |
| Sun H, et al.(2022) TRIB2 regulates the expression of miR 33a 5p through the ERK/c Fos pathway to affect the imatinib resistance of chronic myeloid leukemia cells.Int J Oncol 60(5):49. | 2022 | がん研究 | 血液がん |
| Wang YH, et al.(2022) Golgin Imh1 and GARP complex cooperate to restore the impaired SNARE recycling transport induced by ER stress.Cell Rep 38(12):110488. | 2022 | その他 | |
| Park H, et al.(2022) miR-200c suppression increases tau hyperphosphorylation by targeting 14-3-3γ in early stage of 5xFAD mouse model of Alzheimer's disease.Int J Biol Sci 18(5):2220-2234. | 2022 | 神経生物学 | |
| Mallard J, et al.(2022) Chemotherapy impairs skeletal muscle mitochondrial homeostasis in early breast cancer patients.J Cachexia Sarcopenia Muscle Apr 4 doi: 10.1002/jcsm.12991 | 2022 | がん研究 | 乳がん |
| Boltz F, et al.(2022) Nimodipine Exerts Beneficial Effects on the Rat Oligodendrocyte Cell Line OLN-93.Brain Sci 12(4):476. | 2022 | 神経生物学 | |
| Zorzan E, et al.(2022) Hypermethylation-Mediated Silencing of CIDEA, MAL and PCDH17 Tumour Suppressor Genes in Canine DLBCL: From Multi-Omics Analyses to Mechanistic Studies.Int J Mol Sci 23(7):4021. | 2022 | がん研究 | 一般 |
| Park SK, et al.(2022) Peanut (Arachis hypogaea) sprout prevents high-fat diet-induced cognitive impairment by improving mitochondrial function.Sci Rep 12(1):6213. | 2022 | 神経生物学 | |
| Zhang K, et al.(2022) Sevoflurane attenuates hepatic ischemia reperfusion injury by the miR-122/Nrf2 pathway.Ann Transl Med 10(6):350. | 2022 | その他 | |
| Ponterio G, et al.(2022) Alpha-Synuclein is Involved in DYT1 Dystonia Striatal Synaptic Dysfunction.Mov Disord Apr 14 doi: 10.1002/mds.29024. | 2022 | 神経生物学 | |
| Yang HD, et al.(2022) Effect of Neiyi Prescription of QIU on autophagy and angiogenic ability of endometriosis via the PPARγ/NF-κB signaling pathway.Arch Gynecol Obstet Apr 3 doi: 10.1007/s00404-022-06537-w. | 2022 | 細胞シグナル伝達 | |
| Barros-Álvarez X, et al.(2022) The tethered peptide activation mechanism of adhesion GPCRs.Nature Apr 13 doi: 10.1038/s41586-022-04575-7. | 2022 | 構造生物学／タンパク質相互作用 | |
| Tang B, et al.(2022) xCT contributes to colorectal cancer tumorigenesis through upregulation of the MELK oncogene and activation of the AKT/mTOR cascade.Cell Death Dis 13(4):373. | 2022 | がん研究 | 大腸がん |
| Debnath S, et al.(2022) Eriodictyol mediated selective targeting of the TNFR1/FADD/TRADD axis in cancer cells induce apoptosis and inhibit tumor progression and metastasis.Transl Oncol 21:101433. | 2022 | がん研究 | 一般 |
| Tabler CO, et al.(2022) The HIV-1 Viral Protease Is Activated during Assembly and Budding Prior to Particle Release.J Virol Apr 19 doi: 10.1128/jvi.02198-21. | 2022 | 微生物およびモデル生物 | |
| Katsumura S, et al.(2022) Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure.Cell Metab 34(4):564-580.e8. | 2022 | その他 | |
| Andhare DS, et al.(2022) Protein-protein interactions on membrane surfaces analysed using pull-downs with supported bilayers on silica beads.J Membr Biol Feb 28 doi: 10.1007/s00232-022-00222-4. | 2022 | メソッド開発 | |
| Uthailak N, et al.(2022) Production of recombinant β-glucocerebrosidase in wild-type and glycoengineered transgenic Nicotiana benthamiana root cultures with different N-glycan profiles.J Biosci Bioeng Feb 18 doi: 10.1016/j.jbiosc.2022.01.002. | 2022 | 植物科学 | |
| Parashar D, et al.(2022) Patient-Derived Ovarian Cancer Spheroids Rely on PI3K-AKT Signaling Addiction for Cancer Stemness and Chemoresistance.Cancers (Basel) 14(4):958. | 2022 | がん研究 | 一般 |
| Park JS, et al.(2022) Proteomic changes in broiler liver by body weight differences under chronic heat stress.Poultry Science Feb 23 doi: 10.1016/j.psj.2022.101794. | 2022 | その他 | |
| Bakrania BA, et al.(2022) Sustained Elevated Circulating Activin A Impairs Global Longitudinal Strain in Pregnant Rats: A Potential Mechanism for Preeclampsia-Related Cardiac Dysfunction.Cells 11(4):742. | 2022 | その他 | |
| Singh V, et al.(2022) Sepsis downregulates aortic Notch signaling to produce vascular hyporeactivity in mice.Sci Rep 12(1):2941 | 2022 | 細胞シグナル伝達 | |
| Kiss E, et al.(2022) Methyl Donors Reduce Cell Proliferation by Diminishing Erk-Signaling and NFkB Levels, While Increasing E-Cadherin Expression in Panc-1 Cell Line | 2022 | がん研究 | 膵臓がん |
| Budayeva HG, et al.(2022) Phosphoproteome Profiling of the Receptor Tyrosine Kinase MuSK Identifies Tyrosine Phosphorylation of Rab GTPases.Mol Cell Proteomics Feb 25 doi: 10.1016/j.mcpro.2022.100221. | 2022 | 細胞シグナル伝達 | |
| Hoang ATN, et al.(2022) Casein kinase I inhibitor D4476 influences autophagy and apoptosis in chloroquine-induced adult retinal pigment epithelial-19 cells.Exp Eye Res 218:109004. | 2022 | 細胞シグナル伝達 | |
| Dong Q, et al.(2022) Sensitive and selective detection of Mucin1 in pancreatic cancer using hybridization chain reaction with the assistance of Fe3O4@ polydopamine nanocomposites.J Nanobiotechnology 20(1):94. | 2022 | がん研究 | 膵臓がん |
| Moon SY, et al.(2022) Fraxinol Stimulates Melanogenesis in B16F10 Mouse Melanoma Cells through CREB/MITF Signaling.Molecules 27(5):1549. | 2022 | がん研究 | 皮膚がん |
| Cui Z, et al.(2022) miR-103a-3p Silencing Ameliorates Calcium Oxalate Deposition in Rat Kidney by Activating the UMOD/TRPV5 Axis.Dis Markers 2022:2602717. | 2022 | その他 | |
| Ma X, et al.(2022) Dimeric G-Quadruplex: An Efficient Probe for Ultrasensitive Fluorescence Detection of Mustard Compounds.Anal Chem 94(9):4112-4118. | 2022 | メソッド開発 | |
| Shahi I, et al.(2022) Genome-Wide CRISPR-Cas9 Screen Does Not Identify Host Factors Modulating Streptococcus agalactiae β-Hemolysin/Cytolysin-Induced Cell Death.Microbiol Spectr 10(1):e0218621. | 2022 | CRISPR | |
| Tolomeo AM, et al.(2022) Temperature-Related Effects of Myocardial Protection Strategies in Swine Hearts after Prolonged Warm Ischemia.Antioxidants 11(3):476. | 2022 | その他 | |
| Yang W, et al.(2022) Immune-responsive gene 1 protects against liver injury caused by concanavalin A via the activation Nrf2/HO-1 pathway and inhibition of ROS activation pathways.Free Radic Biol Med 182:108-118. | 2022 | 細胞シグナル伝達 | |
| Vougioukalaki M, et al.(2022) Cell adhesion tunes inflammatory TPL2 kinase signal transduction.Cell Mol Life Sci 79(3):156. | 2022 | 細胞シグナル伝達 | |
| Wang H, et al.(2022) Bisphosphonate of Zoledronate Has Antiapoptotic Effect on Hypoxia/Reoxygenation Injury in Human Embryonic Stem Cell-Derived Cardiomyocytes Through Trk Signaling Pathway.Cell Biochem Biophys doi: 10.1007/s12013-021-01031-7. | 2022 | 細胞シグナル伝達 | |
| Lee J, et al.(2022) Improved stability of vitamin D3 encapsulated in whey protein isolate microgels.Int Dairy J 129: 105351. | 2022 | その他 | |
| Song ES, et al.(2022) Novel Corneal Endothelial Cell Carrier Couples a Biodegradable Polymer and a Mesenchymal Stem Cell-Derived Extracellular Matrix.ACS Appl Mater Interfaces 14(10):12116-12129. | 2022 | 幹細胞 | |
| Rotoli BM, et al.(2022) Desmopressin Stimulates Nitric Oxide Production in Human Lung Microvascular Endothelial Cells.Biomolecules 12(3): 389. | 2022 | その他 | |
| Cui X, et al.(2022) A clinical study on the effects of dexmedetomidine and propofol on erythrocyte deformability during anaesthesia.Pak J Pharm Sci 29(5):1615-1618. | 2022 | その他 | |
| Nguyen XP, et al.(2022) Expression of FMRpolyG in Peripheral Blood Mononuclear Cells of Women with Fragile X Mental Retardation 1 Gene Premutation.Genes 13(3): 451. | 2022 | その他 | |
| Hou W, et al.(2022) Integrin subunit beta 8 contributes to lenvatinib resistance in HCC.Hepatol Commun Mar 3 doi: 10.1002/hep4.1928. | 2022 | がん研究 | 肝臓がん |
| Ren J, et al.(2022) Generation of immunodeficient pig with hereditary tyrosinemia type 1 and their preliminary application for humanized liver.Cell Biosci 12(1):26. | 2022 | CRISPR | |
| Barilli A, et al.(2022) Immune-Mediated Inflammatory Responses of Alveolar Epithelial Cells: Implications for COVID-19 Lung Pathology.Biomedicines 10(3): 618. | 2022 | 細胞シグナル伝達 | |
| Pinel K, et al.(2022) Are the Main Methionine Sources Equivalent? A Focus on DL-Methionine and DL-Methionine Hydroxy Analog Reveals Differences on Rainbow Trout Hepatic Cell Line Functions.Int. J. Mol.Sci.23(6): 2935. | 2022 | その他 | |
| Kim EH, et al.(2022) PDL1-binding peptide/anti-miRNA21 conjugate as a therapeutic modality for PD-L1high tumors and TAMs.J Control Release 345:62-74. | 2022 | がん研究 | 皮膚がん |
| Daruich A, et al.(2022) Comparative Analysis of Urso-and Tauroursodeoxycholic Acid Neuroprotective Effects on Retinal Degeneration Models.Pharmaceuticals 15(3): 334. | 2022 | 神経生物学 | |
| Teng JW, et al.(2022) Icariin triggers osteogenic differentiation of bone marrow stem cells by up-regulating miR-335–5p.Exp Cell Res 414(2):113085. | 2022 | 幹細胞 | |
| Zhang X, et al.(2022) MiR-874-3p represses the migration and invasion yet promotes the apoptosis and cisplatin sensitivity via being sponged by long intergenic non-coding RNA 00922 and targeting Glycerophosphodiester Phosphodiesterase Domain Containing 5 (GDPD5) in gastric cancer cells.Bioengineered 13(3):7082-7104 | 2022 | がん研究 | 胃がん |
| Lee S, et al.(2022) Quantitative analysis of PACAP-38 and amyloid beta composition using a dual reaction in reduced graphene oxide biosensor to verify the neuroprotective role of PACAP-38.Sens Actuators B Chem 361: 131727. | 2022 | 神経生物学 | |
| S Olivera-Bravo S, et al.(2022) Neuroprotective effects of violacein in a model of inherited amyotrophic lateral sclerosis.Sci Rep 12(1):4439. | 2022 | 神経生物学 | |
| Verkest C, et al.(2022) Intrinsically disordered intracellular domains control key features of the mechanically-gated ion channel PIEZO2.Nat Commun 13(1):1365. | 2022 | 構造生物学／タンパク質相互作用 | |
| Ratti S, et al.(2022) Impact of phospholipase C β1 in glioblastoma: a study on the main mechanisms of tumor aggressiveness.Cell Mol Life Sci 79(4):195. | 2022 | がん研究 | 脳腫瘍 |
| Südfeld C, et al.(2022) Accumulation of medium chain fatty acids in Nannochloropsis oceanica by heterologous expression of Cuphea palustris thioesterase FatB1.Algal Res 64: 102665. | 2022 | 微生物およびモデル生物 | |
| Kim K, et al.(2022) Hispidulin Ameliorates Endotoxin-Induced Acute Kidney Injury in Mice.Molecules 27(6): 2019. | 2022 | その他 | |
| Prvulovic M, et al.(2022) Calorie restriction changes the anxiety-like behaviour of ageing male Wistar rats in an onset-and duration-dependent manner.Mech Ageing Dev Mar 21 doi: 10.1016/j.mad.2022.111666. | 2022 | その他 | |
| Tanuma S, et al.(2022) A Dual Anti-Inflammatory and Anti-Proliferative 3-Styrylchromone Derivative Synergistically Enhances the Anti-Cancer Effects of DNA-Damaging Agents on Colon Cancer Cells by Targeting HMGB1-RAGE-ERK1/2 Signaling.Int J Mol Sci 23(7): 3426. | 2022 | がん研究 | 結腸がん |
| Milosevic K, et al.(2022) Agmatine Mitigates Inflammation-Related Oxidative Stress in BV-2 Cells by Inducing a Pre-Adaptive Response.Int J Mol Sci 23(7): 3561. | 2022 | 神経生物学 | |
| Chen J, et al.(2022) Polyphenols in Ilex latifolia Thunb. inhibit human lung cancer cell line A549 by regulation of the PI3K-Akt signaling pathway.BMC Complement Med Ther 22(1):85. | 2022 | がん研究 | 肺がん |
| Clark KL, et al.(2022) Perfluorooctanoic acid promotes proliferation of the human granulosa cell line HGrC1 and alters expression of cell cycle genes and Hippo pathway effector YAP1.Reprod Toxicol Mar 25 doi: 10.1016/j.reprotox.2022.03.011. | 2022 | 細胞シグナル伝達 | |
| Arakawa M, et al.(2022) Flavivirus recruits the valosin-containing protein (VCP)/NPL4 complex to induce stress granule disassembly for efficient viral genome replication.J Biol Chem Jan 18 doi: 10.1016/j.jbc.2022.101597. | 2022 | 構造生物学／タンパク質相互作用 | |
| Jang DG, et al.(2022) Integrin β-like 1 protein (ITGBL1) promotes cell migration by preferentially inhibiting integrin-ECM binding at the trailing edge.Genes Genomics Jan 23 doi: 10.1007/s13258-021-01204-x. | 2022 | その他 | |
| Korobeynikov VA and Lyashchenko AK/ (2022) Antisense oligonucleotide silencing of FUS expression as a therapeutic approach in amyotrophic lateral sclerosis.Nat Med 28(1):104-116. | 2022 | 神経生物学 | |
| Zigrossi A , et al.(2022) SELENOF is a new tumor suppressor in breast cancer.Oncogene Jan 27 doi: 10.1038/s41388-021-02158-w. | 2022 | がん研究 | 乳がん |
| Yang HH, et al.(2022) Anti-Excitotoxic Effects of N-Butylidenephthalide Revealed by Chemically Insulted Purkinje Progenitor Cells Derived from SCA3 iPSCs.Int. J. Mol.Sci 23(3):1391. | 2022 | 幹細胞 | |
| Wang L, et al.(2022) FOXM1-induced TYMS upregulation promotes the progression of hepatocellular carcinoma.Cancer Cell Int 22(1):47. | 2022 | がん研究 | 肝臓がん |
| Nagaoka M, et al.(2022) Targeted Delivery of Immunostimulatory CpG Oligodeoxynucleotides to Antigen-Presenting Cells in Draining Lymph Nodes by Stearic Acid Modification and and Nanostructurization.Int. J. Mol.Sci.23(3): 1350. | 2022 | 構造生物学／タンパク質相互作用 | |
| Melnikova AME, et al.(2022) The p. Glu787Lys variant in the GRIA3 gene causes developmental and epileptic encephalopathy mimicking structural epilepsy in a female patient.Eur J Med Genet 65(3):104442 | 2022 | 神経生物学 | |
| Li Y, et al.(2022) Cerebrospinal Fluid Extracellular Vesicles with Distinct Properties in Autoimmune Encephalitis and Herpes Simplex Encephalitis.Mol Neurobiol Jan 27 doi: 10.1007/s12035-021-02705-2. | 2022 | 神経生物学 | |
| Skertich NJ, et al.(2022) Expression of Immunomodulatory Checkpoint Molecules in Drug-Resistant Neuroblastoma: An Exploratory Study.Cancers 14(3):751. | 2022 | がん研究 | 一般 |
| Jia X, et al.(2022) Facile one-step synthesis of NIR-Responsive siRNA-Inorganic hybrid nanoplatform for imaging-guided photothermal and gene synergistic therapy.Biomaterials 282:121404. | 2022 | メソッド開発 | |
| Sia KC, et al.(2022) First use of gene therapy to treat growth hormone resistant dwarfism in a mouse model.Gene Ther Feb 1 doi: 10.1038/s41434-022-00313-w. | 2022 | メソッド開発 | |
| Lee HK, et al.(2022) Differential release of extracellular vesicle tRNA from oxidative stressed renal cells and ischemic kidneys.Sci Rep 12(1):1646. | 2022 | 疾病研究 | バイオマーカー研究 |
| Cheng L, et al.(2022) Long noncoding RNA RP11-241J12.3 targeting pyruvate carboxylase promotes hepatocellular carcinoma aggressiveness by disrupting pyruvate metabolism and the DNA mismatch repair system.Mol Biomed 3(1):4. | 2022 | がん研究 | 肝臓がん |
| Sun Y, et al.(2022) Pharmacologic induction of PGC‐1α stimulates fetal haemoglobin gene expression.Br J Haematol Feb 4 doi: 10.1111/bjh.18042. | 2022 | その他 | |
| Pakarinen E, et al.(2022) CDNF and MANF regulate ER stress in a tissue-specific manner.Cell Mol Life Sci 79(2):124. | 2022 | 細胞シグナル伝達 | |
| Kang D, et al.(2022) Selenophosphate synthetase 1 deficiency exacerbates osteoarthritis by dysregulating redox homeostasis.Nat Commun 13(1):779. | 2022 | その他 | |
| Watanabe H, et al.(2022) Transcription factor Hhex negatively regulates osteoclast differentiation by controlling cyclin‐dependent kinase inhibitors.JBMR Plus Jan 28 doi: 10.1002/jbm4.10608. | 2022 | 細胞シグナル伝達 | |
| Ljungblad L, et al.(2022) Omega-3 fatty acids decrease CRYAB, production of oncogenic prostaglandin E2 and suppress tumor growth in medulloblastoma.Life Sci 295:120394. | 2022 | がん研究 | 脳腫瘍 |
| Omura CM, et al.(2022) Decrease of IL-1β and TNF in the Spinal Cord Mediates Analgesia Produced by Ankle Joint Mobilization in Complete Freund Adjuvant-Induced Inflammation Mice Model.Front Physiol 12:816624. | 2022 | その他 | |
| Xu Z, et al.(2022) Cabazitaxel suppresses the proliferation and promotes the apoptosis and radiosensitivity of castration-resistant prostate cancer cells by inhibiting PI3K/AKT pathway.Am J Transl Res 14(1):166-181. | 2022 | がん研究 | 一般 |
| Salamone IM, et al.(2022) Intermittent glucocorticoid treatment enhances skeletal muscle performance through sexually dimorphic mechanisms.J Clin Invest Feb 10 doi: 10.1172/JCI149828. | 2022 | その他 | |
| Manna VJ, et al.(2022) The dynamic nature of the Coronavirus receptor, angiotensin-converting enzyme 2 (ACE2) in differentiating airway epithelia.BBA Adv 2:100044. | 2022 | 微生物およびモデル生物 | |
| Li Y, et al.(2022) LncRNA LINC01315 silencing modulates cancer stem cell properties and epithelial-to-mesenchymal transition in colorectal cancer via miR-484/DLK1 axis.Cell Cycle Feb 13 doi: 10.1080/15384101.2022.2033415. | 2022 | がん研究 | 大腸がん |
| Czajka TF, et al.(2022) Single-Domain Antibodies for Intracellular Toxin Neutralization.Methods Mol Biol 2446:469-487. | 2022 | メソッド開発 | |
| Casas-Sanchez A, et al.(2022) Inhibition of Protein N-Glycosylation Blocks SARS-CoV-2 Infection. mBio 13(1):e0371821. | 2022 | 微生物およびモデル生物 | |
| Mandi CS, et al.(2022) Cleavage of Abasic Sites in DNA by an Aminoquinoxaline Compound: Augmented Cytotoxicity and DNA Damage in Combination with an Anticancer Drug Chlorambucil in Human Colorectal Carcinoma Cells.ACS Omega Feb 18 doi: 10.1021/acsomega.1c04962. | 2022 | がん研究 | 大腸がん |
| Rudy MJ, et al.(2022) Density Analysis of Enterovirus D68 Shows Viral Particles Can Associate with Exosomes.Microbiol Spectr 10(1):e0245221. | 2022 | 微生物およびモデル生物 | |
| Liu M, et al.(2022) miR-197 Participates in Lipopolysaccharide-Induced Cardiomyocyte Injury by Modulating SIRT1.Cardiol Res Pract Feb 17 doi: 10.1155/2022/7687154 | 2022 | その他 | |
| Ahn SH, et al.(2022) Rhynchosia volubilis Promotes Cell Survival via cAMP-PKA/ERK-CREB Pathway.Pharmaceuticals (Basel) 15(1):73. | 2022 | 細胞シグナル伝達 | |
| Choi YH , et al.(2022) Antiandrogenic activity of Riboflavin 5′-phosphate (FMN) in 22Rv1 and LNCaP human prostate cancer cell lines.Eur J Pharmacol Jan 5 doi: 10.1016/j.ejphar.2022.174743. | 2022 | がん研究 | 一般 |
| Furuyama W, et al.(2022) Rapid Protection from COVID-19 in Nonhuman Primates Vaccinated Intramuscularly but Not Intranasally with a Single Dose of a Vesicular Stomatitis Virus-Based Vaccine. mBio Jan 11 doi: 10.1128/mbio.03379-21. | 2022 | その他 | |
| Harlaar N, et al.(2022) Conditional immortalization of human atrial myocytes for the generation of in vitro models of atrial fibrillation.Nat Biomed Eng Jan 6 doi: 10.1038/s41551-021-00827-5. | 2022 | その他 | |
| Kono M, et al.(2022) Immunomodulation via FGFR inhibition augments FGFR1 targeting T-cell based antitumor immunotherapy for head and neck squamous cell carcinoma.Oncoimmunology 11(1):2021619. | 2022 | がん研究 | 扁平上皮がん |
| Lee H, et al.(2022) Soybean-Derived Peptides Attenuate Hyperlipidemia by Regulating Trans-Intestinal Cholesterol Excretion and Bile Acid Synthesis.Nutrients 14(1):95. | 2022 | 植物科学 | |
| Morgan SM, et la. (2022) The three-dimensional structure of Epstein-Barr virus genome varies by latency type and is regulated by PARP1 enzymatic activity.Nat Commun 13(1):187. | 2022 | 構造生物学／タンパク質相互作用 | |
| Starikova AV, et al.(2022) Therapeutic potential of highly functional codon-optimized microutrophin for muscle-specific expression.Sci Rep 12(1):848. | 2022 | Mitochondrial studies | |
| Weixler D, et al.(2022) Recombinant production of the lantibiotic nisin using Corynebacterium glutamicum in a two-step process.Microb Cell Fact 21(1):11. | 2022 | 微生物およびモデル生物 | |
| Yin J, et al.(2022) Development of a whole-cell biosensor for detection of antibiotics targeting bacterial cell envelope in Bacillus subtilis.Appl Microbiol Biotechnol 106(2):789-798. | 2022 | 微生物およびモデル生物 | |
| Zhong J, et al.(2022) KCNIP3 silence promotes proliferation and epithelial-mesenchymal transition of papillary thyroid carcinoma through activating Wnt/β-catenin pathway.Tissue and Cell 75:101739. | 2022 | がん研究 | 一般 |
| Acar NV, et al.(2021) An investigation of different intracellular parameters for Inborn Errors of Metabolism: Cellular stress, antioxidant response and autophagy.Free Radic Biol Med 179:190-199. | 2021 | その他 | |
| Adhikari A, et al, (2021) Myogenin is required for assembly of the transcription machinery on muscle genes during skeletal muscle differentiation.PLoS One 16(1):e0245618. | 2021 | その他 | |
| Ali A, et al.(2021) Inhibition of HDACs Suppresses Cell Proliferation and Cell Migration of Gastric Cancer by Regulating E2F5 Targeting BCL2.Life (Basel) 11(12):1425. | 2021 | がん研究 | 胃がん |
| Almeida-Toledano L, et al.(2021) Epigallocatechin Gallate Ameliorates the Effects of Prenatal Alcohol Exposure in a Fetal Alcohol Spectrum Disorder-Like Mouse Model.Int J Mol Sci 22(2):715. | 2021 | その他 | |
| Altman T, et al.(2021) Axonal TDP-43 condensates drive neuromuscular junction disruption through inhibition of local synthesis of nuclear encoded mitochondrial proteins.Nat Commun 12(1):6914. | 2021 | 神経生物学 | |
| An X, et al.(2021) Discovery of a widespread presence bunyavirus that may have symbiont‐like relationships with different species of aphids.Insect Sci Dec 7 doi: 10.1111/1744-7917.12989. | 2021 | 微生物およびモデル生物 | |
| Arunkumar R, et al.(2021) Lutein and zeaxanthin reduce A2E and iso-A2E levels and improve visual performance in Abca4−/−/bco2−/− double knockout mice.Exp Eye Res 209:108680. | 2021 | 神経生物学 | |
| Avila H, et al.(2021) Intracellular Dynamin Elastin-like Polypeptides Assemble into Rodlike, Spherical, and Reticular Dynasomes.Biomacromolecules Dec 16 doi: 10.1021/acs.biomac.1c01251. | 2021 | 構造生物学／タンパク質相互作用 | |
| Bade AN, et al.(2021) Dolutegravir Inhibition of Matrix Metalloproteinases Affects Mouse Neurodevelopment.Mol Neurobiol Aug 14 doi: 10.1007/s12035-021-02508-5. | 2021 | 神経生物学 | |
| Bae IY, et al.(2021) TIMP‐1‐expressing breast tumor spheroids for the evaluation of drug penetration and efficacy.Bioeng Transl Med Dec 23 doi: 10.1002/btm2.10286. | 2021 | がん研究 | 乳がん |
| Baker l, et al.(2021) Fidgetin-like 2 negatively regulates axonal growth and can be targeted to promote functional nerve regeneration.JCI Insight Apr 19 doi: 10.1172/jci.insight.138484. | 2021 | 神経生物学 | |
| Barilli A, et al.(2021) Organic cation transporters (OCTs/OCTNs) in human primary alveolar epithelial cells.Biochem Biophys Res Commun 576:27-32. | 2021 | その他 | |
| Barua R, et al.(2021) Bioinformatics and Functional Analyses Implicate Potential Roles for EOGT and L-fringe in Pancreatic Cancers.Molecules 26(4):882. | 2021 | がん研究 | 膵臓がん |
| Beveridge DJ, et al.(2021) The tumor suppressor miR-642a-5p targets Wilms Tumor 1 gene and cell-cycle progression in prostate cancer.Sci Rep 11(1):18003. | 2021 | がん研究 | 一般 |
| Bian S, et al.(2021) Knockdown of p62/sequestosome enhances ginsenoside Rh2-induced apoptosis in cervical cancer HeLa cells with no effect on autophagy.Biosci Biotechnol Biochem, Feb 5 doi:10.1093/bbb/zbab019. | 2021 | 細胞シグナル伝達 | |
| Burgess HM, et al.(2021) Targeting the m6A RNA modification pathway blocks SARS-CoV-2 and HCoV-OC43 replication.Genes Dev 35(13-14):1005-1019. | 2021 | 微生物およびモデル生物 | |
| Burr SD, et al.(2021) Rap1a Regulates Cardiac Fibroblast Contraction of 3D Diabetic Collagen Matrices by Increased Activation of the AGE/RAGE Cascade.Cells 10(6) 1286 | 2021 | 細胞シグナル伝達 | |
| Cai S, et al.(2021) Integrative analysis and experiments to explore angiogenesis regulators correlated with poor prognosis, immune infiltration and cancer progression in lung adenocarcinoma.J Transl Med 19(1):361. | 2021 | がん研究 | 肺がん |
| Carano F, et al.(2021) Assessment of the structural and functional characteristics of human mesenchymal stem cells associated with a prolonged exposure of morphine.Sci Rep 11(1):19248. | 2021 | 幹細胞 | |
| Carinci M, et al.(2021) TFG binds LC3C to regulate ULK1 localization and autophagosome formation.EMBO J May 1 doi: 10.15252/embj.2019103563 | 2021 | 細胞シグナル伝達 | |
| Carminita E, et al.(2021) DNAse-dependent, NET-independent pathway of thrombus formation in vivo.Proc Natl Acad Sci USA 118(28):e2100561118. | 2021 | その他 | |
| Chalise U, et al.(2021) S100A9 is a functional effector of infarct wall thinning after myocardial infarction.Am J Physiol Heart Circ Physiol Dec 10 doi: 10.1152/ajpheart.00475.2021. | 2021 | その他 | |
| Chang H, et al.(2021) PARP1 Is Targeted by miR-519a-3p and Promotes the Migration, Invasion, and Tube Formation of Ovarian Cancer Cells.Cancer Biother Radiopharm May 18 doi: 10.1089/cbr.2020.4394 | 2021 | がん研究 | 卵巣がん |
| Chen F, et al.(2021) Prognostic plasma exosomal microRNA biomarkers in patients with substance use disorders presenting comorbid with anxiety and depression.Sci Rep 11(1):6271. | 2021 | 疾病研究：バイオマーカー研究 | |
| Chen L, et al.(2021) Downregulation of GTSE1 leads to the inhibition of proliferation, migration, and Warburg effect in cervical cancer by blocking LHDA expression.J Obstet Gynaecol Res Sep 5 doi: 10.1111/jog.15000. | 2021 | がん研究 | 一般 |
| Chen M, et al.(2021) Downregulation of triggering receptor expressed on myeloid cells 1 inhibits invasion and migration of liver cancer cells by mediating macrophage polarization.Oncol Rep 45(4):1-12. | 2021 | がん研究 | 肝臓がん |
| Cheng TY, et al.(2021) β-(1→ 4) Mannobiose Acts as an Immunostimulatory Molecule in Murine Dendritic Cells by Binding the TLR4/MD-2 Complex.Cells Jul 5 doi: 10.3390/cells10071774. | 2021 | 神経生物学 | |
| Cherngwelling R, et al.(2021) Agomelatine protects against obesity-induced renal injury by inhibiting endoplasmic reticulum stress/apoptosis pathway in rats.Toxicol Appl Pharmacol 425:115601. | 2021 | 細胞シグナル伝達 | |
| Chompunud Na Ayudhya C, et al.(2021) MRGPRX2 Activation by Rocuronium: Insights from Studies with Human Skin Mast Cells and Missense Variants.Cells 10(1):156. | 2021 | その他 | |
| Civera-Tregón A, et al.(2021) Mitochondria and calcium defects correlate with axonal dysfunction in GDAP1-related Charcot-Marie-Tooth mouse model.Neurobiol Dis Feb 11 doi: 10.1016/j.nbd.2021.105300. | 2021 | 神経生物学 | |
| Contreras L, et al.(2021) Three novel piperidones exhibit tumor-selective cytotoxicity on leukemia cells via protein degradation and stress-mediated mechanisms.Pharmacol Rep Aug 26 doi: 10.1007/s43440-021-00322-3. | 2021 | がん研究 | 一般 |
| D'Acunzo, P, et al, (2021) Mitovesicles are a novel population of extracellular vesicles of mitochondrial origin altered in Down syndrome.Sci Adv 7(7):eabe5085. | 2021 | 神経生物学 | |
| Dai C, et al.(2021) A non‐translational role of threonyl‐tRNA synthetase in regulating JNK signaling during myogenic differentiation.FASEB J 35(10):e21948. | 2021 | 細胞シグナル伝達 | |
| Danac JMC, et al.(2021) CircPVT1 attenuates negative regulation of NRAS by let-7 and drives cancer cells towards oncogenicity.Sci Rep 11(1):9021 | 2021 | がん研究 | その他 |
| Daruich A, et al.(2021) Oral Ursodeoxycholic Acid Crosses the Blood Retinal Barrier in Patients with Retinal Detachment and Protects Against Retinal Degeneration in an Ex Vivo Model.Neurotherapeutics Feb 3 doi: 10.1007/s13311-021-01009-6. | 2021 | 薬剤機構 | |
| Das P, et al.(2021) Glyceraldehyde-3-phosphate dehydrogenase present in extracellular vesicles from Leishmania major suppresses host TNF-alpha expression.J Biol Chem Sep 14 doi: 10.1016/j.jbc.2021.101198. | 2021 | 微生物およびモデル生物 | |
| Delgado-Peraza F, et al.(2021) Neuronal and Astrocytic Extracellular Vesicle Biomarkers in Blood Reflect Brain Pathology in Mouse Models of Alzheimer's Disease.Cells 10(5):993 | 2021 | 神経生物学 | |
| Demonbreun AR, et al.(2021) Anti-latent TGFβ binding protein 4 antibody improves muscle function and reduces muscle fibrosis in muscular dystrophy.Sci Transl Med 13(610):eabf0376. | 2021 | 薬剤機構 | |
| Di Filippo M, et al.(2021) Interleukin-17 affects synaptic plasticity and cognition in an experimental model of multiple sclerosis.Cell Rep 37(10):110094. | 2021 | 神経生物学 | |
| Diller T, et al.(2021) Biological Validation of a Novel Process and Product for Quantitating Western Blots.J Biotechnol 326: 52–60. | 2021 | メソッド開発 | |
| Dong P, et al.(2021) Runjing Decoction alleviated cyclophosphamide‐induced oligoasthenospermia rats by inhibiting cell apoptosis via RXFP1/AKT/FOXO1 pathway.Andrologia Aug 16 doi: 10.1111/and.14216 | 2021 | 細胞シグナル伝達 | |
| Douglass M, et al.(2021) EXPRESS: L-citrulline increases arginase II protein levels and arginase activity in hypoxic piglet pulmonary artery endothelial cells.Pulm Circ Mar 16 doi: 10.1177/20458940211006289. | 2021 | その他 | |
| Dupont L, et al.(2021) The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr.Cell Host Microbe S1931-3128(21)00101-3. | 2021 | その他 | |
| Ebelt ND, et al.(2021) Collagenase-Expressing Salmonella Targets Major Collagens in Pancreatic Cancer and Improves Immune Checkpoint Blockade.Cancers (Basel) 13(14): 3565. | 2021 | がん研究 | 膵臓がん |
| F Zhang F, et al.(2021) Crocin ameliorates atherosclerosis by promoting the reverse cholesterol transport and inhibiting the foam cell formation via regulating PPARγ/LXR-α.Cell Cycle Jan 3 doi: 10.1080/15384101.2021.2015669. | 2021 | その他 | |
| Fasolato L, et al.(2021) An Iron Shield to Protect Epigallocatehin-3-Gallate from Degradation: Multifunctional Self-Assembled Iron Oxide Nanocarrier Enhances Protein Kinase CK2 Intracellular Targeting and Inhibition.Pharmaceutics 13(8):1266. | 2021 | 構造生物学とタンパク質相互作用 | |
| Frazier TW, et al.(2021) Cross-level analysis of molecular and neurobehavioral function in a prospective series of patients with germline heterozygous PTEN mutations with and without autism.Mol Autism 12(1):5. | 2021 | 疾病研究：バイオマーカー研究 | |
| Freeman AJ, et al.(2021) HOIP limits anti‐tumor immunity by protecting against combined TNF and IFN‐gamma‐induced apoptosis.EMBO Rep Sep 1 doi: 10.15252/embr.202153391. | 2021 | がん研究 | 皮膚がん |
| Fu T, et al.(2021) Silencing lncRNA LINC01410 suppresses cell viability yet promotes apoptosis and sensitivity to temozolomide in glioblastoma cells by inactivating PTEN/AKT pathway via targeting miR-370-3p.Immunopharmacol Immunotoxicol Aug 26 doi: 10.1080/08923973.2021.1966031. | 2021 | がん研究 | 脳腫瘍 |
| Fujiwara S, et al.(2021) Chemical-gas sterilization of external surface of polymer-based prefilled syringes and its effect on stability of model therapeutic protein.J Pharm Sci Sep 6 doi: 10.1016/j.xphs.2021.09.003. | 2021 | 構造生物学／タンパク質相互作用 | |
| Furuyama W, et al.(2021) The Ebola virus soluble glycoprotein contributes to viral pathogenesis by activating the MAP kinase signaling pathway.PLoS Pathog 17(9):e1009937. | 2021 | 細胞シグナル伝達 | |
| G Hu, et al.(2021) Light-driven CO2 sequestration in Escherichia coli to achieve theoretical yield of chemicals.Nature Catalysis 4: 395–406. | 2021 | 微生物およびモデル生物 | |
| Gao J, et al.(2021) Morroniside Promotes PGC-1α-Mediated Cholesterol Efflux in Sodium Palmitate or High Glucose-Induced Mouse Renal Tubular Epithelial Cells.Biomed Res Int 2021:9942152. | 2021 | その他 | |
| Gao X, et al.(2021) Gambogic acid protects LPS-induced apoptosis and inflammation in a cell model of neonatal pneumonia through the regulation of TrkA/Akt signaling pathway.BMC Pharmacol Toxicol 22(1):28 | 2021 | 細胞シグナル伝達 | |
| Garrido‐Jimenez S, et al.(2021) p53 regulation by MDM2 contributes to self‐renewal and differentiation of basal stem cells in mouse and human airway epithelium.FASEB J 35(9):e21816. | 2021 | 幹細胞 | |
| Gaul S, et al.(2021) Extracellular NLRP3 inflammasome particles are internalized by human coronary artery smooth muscle cells and induce pro-atherogenic effects.Sci Rep 11(1):15156.Other https://pubmed.ncbi.nlm.nih.gov/34312415/ | 2021 | その他 | |
| Ge X, et al.(2021) Protective effects of naringin on glucocorticoid-induced osteoporosis through regulating the PI3K/Akt/mTOR signaling pathway.Am J Transl Res 13(6):6330-6341. | 2021 | 細胞シグナル伝達 | |
| George TA, et al.(2021) Liposome-encapsulated anthraquinone improves efficacy and safety in triple negative breast cancer.J Control Release Dec 8 doi: 10.1016/j.jconrel.2021.12.001. | 2021 | がん研究 | 乳がん |
| Grimbert L, et al.(2021) Spatiotemporal AMPKα2 deletion in mice induces cardiac dysfunction, fibrosis and cardiolipin remodeling associated with mitochondrial dysfunction in males only.Biol Sex Differ 12(1):52. | 2021 | Mitochondrial studies | |
| Groveman BR, et al.(2021) Human cerebral organoids as a therapeutic drug screening model for Creutzfeldt-Jakob disease .Sci Rep 11(1):5165. | 2021 | 神経生物学 | |
| Gu Y, et al.(2021) Therapeutic potential of a novel semi-synthetic-sulfated-polysaccharide to suppress inflammatory mediators in P. gingivalis LPS stimulated human monocytes/macrophages.J Inflamm (Lond) 18(1):26. | 2021 | 薬剤機構 | |
| Guettler J, et al.(2021) Maternal platelets pass interstices of trophoblast columns and are not activated by HLA-G in early human pregnancy.I144:103280. | 2021 | その他 | |
| Guo Y, et al.(2021) miR-23a-3p is involved in drug resistance by directly targeting the influx drug transporter organic anion-transporting polypeptide 2.Childs Nerv Syst Mar 29 doi: 10.1007/s00381-021-05146-3. | 2021 | 薬剤機構 | |
| Han H, et al.(2021) MiR-205 Promotes the Viability, Migration, and Tube Formation of Cervical Cancer Cells In Vitro by Targeting GATA3.Cancer Biother Radiopharm Mar 30 doi: 10.1089/cbr.2020.4184 | 2021 | がん研究 | 一般 |
| Hanafi M, et al.(2021) Discovery of a Napabucasin PROTAC as an Effective Degrader of the E3 Ligase ZFP91.J Med Chem 64(3):1626-1648. | 2021 | 細胞シグナル伝達 | |
| Hasan NA, et al.(2021) Measurable genomic changes in Mycobacterium avium subsp. hominissuis after long-term adaptation in Acanthamoeba lenticulata and reduced persistence in in macrophages.J Bacteriol Jan 11 doi: 10.1128/JB.00257-20. | 2021 | 微生物およびモデル生物 | |
| Heltmann-Meyer S, et al.(2021) Gelatin methacryloyl is a slow degrading material allowing vascularization and long-term use in vivo.Biomed Mater Aug 18 doi: 10.1088/1748-605X/ac1e9d. | 2021 | メソッド開発 | |
| Hernandez JJ, et al.(2021) Dodging COVID-19 infection: low expression and localization of ACE2 and TMPRSS2 in multiple donor-derived lines of human umbilical cord-derived mesenchymal stem cells.J Transl Med 19(1):149 | 2021 | 幹細胞 | |
| Hernandez-Santini AC, et al.(2021) Methamphetamine facilitates pulmonary and splenic tissue injury and reduces T cell infiltration in C57BL/6 mice after antigenic challenge.Sci Rep 11(1):8207 | 2021 | その他 | |
| Hesse J, et al.(2021) Mono-ADP-ribosylation sites of human CD73 inhibit its adenosine-generating enzymatic activity.Purinergic Signal Dec 27 doi: 10.1007/s11302-021-09832-4. | 2021 | その他 | |
| Hesse J, et al.(2021) Normoxic induction of HIF‐1α by adenosine‐A2BR signaling in epicardial stromal cells formed after myocardial infarction.FASEB J 35(5):e21517 | 2021 | 細胞シグナル伝達 | |
| Hong MJ, et al.(2021) Regulation of Glycosylphosphatidylinositol-Anchored Protein (GPI-AP) Expression by F-Box/LRR-Repeat (FBXL) Protein in Wheat (Triticum aestivum L.).Plants 10(8), 1606. | 2021 | 植物科学 | |
| Hsueh SC, et al.(2021) N-Adamantyl Phthalimidine: A New Thalidomide-like Drug That Lacks Cereblon Binding and Mitigates Neuronal and Synaptic Loss, Neuroinflammation, and Behavioral Deficits in Traumatic Brain Injury and LPS Challenge. | 2021 | 神経生物学 | |
| Huang CT, et al.(2021) Intravitreal Injection of Long-Acting Pegylated Granulocyte Colony-Stimulating Factor Provides Neuroprotective Effects via Antioxidant Response in a Rat Model of Traumatic Optic Neuropathy.Antioxidants 10(12):1934. | 2021 | 神経生物学 | |
| Huang L, et al.(2021) Circular RNA hsa_circ_0001598 promotes programmed death-ligand-1-mediated immune escape and trastuzumab resistance via sponging miR-1184 in breast cancer cells.Immunol Res Sep 24 doi: 10.1007/s12026-021-09237-w. | 2021 | がん研究 | 乳がん |
| Huang ZN, et al.(2021) Inhibition of p38 Mitogen–Activated Protein Kinase Ameliorates HAP40 Depletion–Induced Toxicity and Proteasomal Defect in Huntington's Disease Model.Mol Neurobiol Jan 25 doi: 10.1007/s12035-020-02280-y. | 2021 | 神経生物学 | |
| Jackson TC, et al.(2021) Hippocampal and Prefrontal Cortical Brain Tissue Levels of Irisin and GDF15 Receptor Subunits in Children.Mol Neurobiol Jan 7 doi: 10.1007/s12035-020-02250-4. | 2021 | その他 | |
| Janke U, et al.(2021) Reconstitution of Functional Integrin αIIbβ3 and Its Activation in Plasma Membrane-Mimetic Lipid Environments.Membranes (Basel) 11(7):499. | 2021 | 構造生物学 | |
| Ji L, et al.(2021) Enhancing L-malate production of Aspergillus oryzae by nitrogen regulation strategy.Appl Microbiol Biotechnol Apr 5 doi: 10.1007/s00253-021-11149-6. | 2021 | 微生物およびモデル生物 | |
| Ji Z, et al.(2021) miR-7a Targets Insulin Receptor Substrate-2 Gene and Suppresses Viability and Invasion of Cells in Diabetic Retinopathy Mice via PI3K-Akt-VEGF Pathway.Diabetes Metab Syndr Obes 14:719-728. | 2021 | 細胞シグナル伝達 | |
| Jia, XB, et al.(2021) Lotus leaf flavonoids induce apoptosis of human lung cancer A549 cells through the ROS/p38 MAPK pathway.Biol Res 54(1):7. | 2021 | がん研究 | 肺がん |
| Jin H, et al.(2021) Gensenoside Rg1 Protects against Lipopolysaccharide-and D-galactose-induced Acute Liver Failure via Suppressing HMGB1-mediated TLR4-NF-κB Pathway.Mol Cell Probes Feb 19 doi: 10.1016/j.mcp.2021.101706. | 2021 | 薬剤機構 | |
| Johar A, et al.(2021) Antibiotic Resistance and Virulence Gene Patterns Associated with Avian Pathogenic Escherichia coli (APEC) from Broiler Chickens in Qatar.Antibiotics 10(5): 564 | 2021 | 微生物およびモデル生物 | |
| Jonuscheit S, et al.(2021) PARP Inhibitors Talazoparib and Niraparib Sensitize Melanoma Cells to Ionizing Radiation.Genes (Basel) 12(6):849. | 2021 | 薬剤機構 | |
| Jung HJ, et al.(2021) TAM mediates adaptation of carbapenem-resistant Klebsiella pneumoniae to antimicrobial stress during host colonization and infection.PLoS Pathog 17(2):e1009309. | 2021 | 微生物およびモデル生物 | |
| Jung YS, et al.(2021) Orphan nuclear receptor ERRγ regulates hepatic TGF-β2 expression and fibrogenic response in CCl4-induced acute liver injury.Arch Toxicol Jun 30 doi: 10.1007/s00204-021-03112-1. | 2021 | その他 | |
| Kalogirou C, et al.(2021) MiR-205-driven downregulation of cholesterol biosynthesis through SQLE-inhibition identifies therapeutic vulnerability in aggressive prostate cancer.Nat Commun 12(1):5066. | 2021 | がん研究 | 前立腺がん |
| Kang H, et al.(2021) Downregulated CLIP3 induces radioresistance by enhancing stemness and glycolytic flux in glioblastoma.J Exp Clin Cancer Res 40(1):282. | 2021 | がん研究 | 脳腫瘍 |
| Kang JS, et al.(2021) Ingestion of Bis (2-ethylhexyl) phthalate (DEHP) during adolescence causes depressive-like behaviors through hypoactive glutamatergic signaling in the medial prefrontal cortex.Environ Pollut 289:117978. | 2021 | 神経生物学 | |
| Kasson S, et al.(2021) Selective monitoring of the protein-free ADP-ribose released by ADP-ribosylation reversal enzymes.PLoS One 16(6):e0254022. | 2021 | メソッド開発 | |
| Kaushal JB, et al.(2021) Repurposing Niclosamide for Targeting Pancreatic Cancer by Inhibiting Hh/Gli Non-Canonical Axis of Gsk3β.Cancers (Basel) 13(13):3105. | 2021 | がん研究 | 膵臓がん |
| Khan SA, et al.(2021) Probing the signaling requirements for naive human pluripotency by high-throughput chemical screening.Cell Rep 35(11):109233. | 2021 | 幹細胞 | |
| Kim DI, et al.(2021) Diesel Exhaust Particulates Enhances Susceptibility of LPS-Induced Acute Lung Injury through Upregulation of the IL-17 Cytokine-Derived TGF-β1/Collagen I Expression and Activation of NLRP3 Inflammasome Signaling in Mice.Biomolecules 11(1):E67. | 2021 | 細胞シグナル伝達 | |
| Kim EA, et al.(2021) Anti-Obesity Effect of Pine Needle Extract on High-Fat Diet-Induced Obese Mice.Plants (Basel) 10(5):837. | 2021 | 植物科学 | |
| Kim H, et al.(2022) Baiap3 regulates depressive behaviors in mice via attenuating dense core vesicle trafficking in subsets of prefrontal cortex neurons.Neurobiol Stress 16:100423. | 2021 | 神経生物学 | |
| Kim JY, et al.(2021) Protective Effects of Bee Venom-Derived Phospholipase A2 against Cholestatic Liver Disease in Mice.Biomedicines 9(8):992. | 2021 | その他 | |
| Kim YR, et al.(2021) Isoegomaketone from Perilla frutescens (L.) Britt Stimulates MAPK/ERK Pathway in Human Keratinocyte to Promote Skin Wound Healing.Evidence-Based Complementary and Alternative Medicine Feb 10 doi: 10.1155/2021/6642606. | 2021 | 薬剤機構 | |
| King WT, et al.(2021) Dynamin-related protein 1 regulates substrate oxidation in skeletal muscle by stabilizing cellular and mitochondrial calcium dynamics.J Biol Chem Sep 13 doi: 10.1016/j.jbc.2021.101196. | 2021 | 細胞シグナル伝達 | |
| Kipkirui E, et al.(2021) Molecular characterization of enterotoxigenic Escherichia coli toxins and colonization factors in children under five years with acute diarrhea attending Kisii Teaching and Referral Hospital, Kenya.Trop Dis Travel Med Vaccines 7(1):31 | 2021 | 微生物およびモデル生物 | |
| Kiss E, et al.(2021) Methyl-Donors Can Induce Apoptosis and Attenuate Both the Akt and the Erk1/2 Mediated Proliferation Pathways in Breast and Lung Cancer Cell Lines.Int J Mol Sci 22(7):3598. | 2021 | 細胞シグナル伝達 | |
| Klid S, et al.(2021) The angiogenic properties of human amniotic membrane stem cells are enhanced in gestational diabetes and associate with fetal adiposity.Stem Cell Res Ther 12(1):608. | 2021 | 幹細胞 | |
| Knorr DY, et al.(2021) Locust Hemolymph Conveys Erythropoietin-Like Cytoprotection via Activation of the Cytokine Receptor CRLF3.Front Physiol April 09 doi: 10.3389/fphys.2021.648245. | 2021 | 細胞シグナル伝達 | |
| Kohno T, et al.(2021) Translocation of LSR from tricellular corners causes macropinocytosis at cell–cell interface as a trigger for breaking out of contact inhibition.FASEB J 35(9):e21742 | 2021 | がん研究 | 子宮体がん |
| Kono M, et al.(2021) Interruption of MDM2 signaling augments MDM2-targeted T cell-based antitumor immunotherapy through antigen-presenting machinery.Cancer Immunol Immunother Apr 18 doi: 10.1007/s00262-021-02940-5. | 2021 | がん研究 | 一般 |
| Kouzminova EA, et al.(2021) Ultraviolet-induced RNA: DNA hybrids interfere with chromosomal DNA synthesis.Nucleic Acids Res Mar 10 doi: 10.1093/nar/gkab147. | 2021 | その他 | |
| Kovačević S, et al.(2021) Fructose-Rich Diet Attenuates Stress-Induced Metabolic Disturbances in the Liver of Adult Female Rats.J Nutr Sep 11 doi: 10.1093/jn/nxab294. | 2021 | その他 | |
| Krüger T, et al.(2021) Single-cell motile behaviour of Trypanosoma brucei in thin-layered fluid collectives.Eur Phys J E Soft Matter 44(3):37. | 2021 | 微生物およびモデル生物 | |
| Latina V, et al.(2021) Systemic delivery of a specific antibody targeting the pathological N-terminal truncated tau peptide reduces retinal degeneration in a mouse model of Alzheimer's Disease.Acta Neuropathol Commun 9: 38 . | 2021 | 神経生物学 | |
| Lee MH, et al.(2021) Anti-Obesity Effect of Licorice Acetone Extract in a Mouse Model of Obesity Induced by a High-Fat Diet.Food Suppl Biomater Health.2021 Mar;1(1):e8. | 2021 | その他 | |
| Lee MN, et al.(2021) Luteolin inhibits NLRP3 inflammasome activation via blocking ASC oligomerization.J Nutr Biochem Mar 8 doi: 10.1016/j.jnutbio.2021.108614. | 2021 | 細胞シグナル伝達 | |
| Lee Y, et al.(2021) Coordinate regulation of the senescent state by selective autophagy.Dev Cell 56(10):1512–1525.e7. | 2021 | その他 | |
| Legscha KJ, et al.(2021) Δ133p53α enhances metabolic and cellular fitness of TCR-engineered T cells and promotes superior antitumor immunity.J Immunother Cancer (6):e001846. | 2021 | がん研究 | その他 |
| Li J, et al.(2021) Identification and validation of a regulatory mutation upstream of the BMP2 gene associated with carcass length in pigs.Genet Sel Evol 53(1):94. | 2021 | その他 | |
| Li L, et al.(2021) Long non‑coding RNA HAND2‑AS1/miR‑106a/PTEN axis re‑sensitizes cisplatin‑resistant ovarian cells to cisplatin treatment.Mol Med Rep 24(5):762. | 2021 | がん研究 | 一般 |
| Li M, et al.(2021) Cytomegalovirus late transcription factor target sequence diversity orchestrates viral early to late transcription. | 2021 | 微生物およびモデル生物 | |
| Li M, et al.(2021) Secreted Expression of mRNA‐Encoded Truncated ACE2 Variants for SARS‐CoV‐2 via Lipid‐Like Nanoassemblies.Adv Mater Jul 18 doi: 10.1002/adma.202101707. | 2021 | その他 | |
| Li N, et al.(2021) Activation of Aquaporin 5 by carcinogenic Helicobacter pylori infection promotes epithelial‐mesenchymal transition via the MEK/ERK pathway.Helicobacter Jul 30 doi: 10.1111/hel.12842. | 2021 | がん研究 | 胃がん |
| Li P, et al.(2021) Melatonin Attenuates ox-LDL-Induced Endothelial Dysfunction by Reducing ER Stress and Inhibiting JNK/Mff Signaling.Oxid Med Cell Longev Mar 4 doi:10.1155/2021/5589612. | 2021 | 薬剤機構 | |
| Li Q, et al.(2021) In vivo PCSK9 gene editing using an all-in-one self-cleavage AAV-CRISPR system.Mol Ther Methods Clin Dev Feb 9 doi: 10.1016/j.omtm.2021.02.005. | 2021 | CRISPR | |
| Li S, et al.(2021) Gossypol ameliorates the IL-1β-induced apoptosis and inflammation in chondrocytes by suppressing the activation of TLR4/MyD88/NF-κB pathway via downregulating CX43.Tissue and Cell Aug 10 doi: 10.1016/j.tice.2021.101621. | 2021 | 細胞シグナル伝達 | |
| Liang M, et al.(2021) Near-infrared fluorescence-guided resection of micrometastases derived from esophageal squamous cell carcinoma using a c-Met-targeted probe in a preclinical xenograft model.J Control Release 332:171–183. | 2021 | がん研究 | 扁平上皮がん |
| Lin C, et al.(2021) Plac1 promotes nasopharyngeal carcinoma cells proliferation, migration and invasion via Furin/NICD/PTEN pathway.Tissue Cell 69:101480. | 2021 | がん研究 | 一般 |
| Lin CC, et al.(2021) Terminal uridyltransferase 7 regulates TLR4-triggered inflammation by controlling Regnase-1 mRNA uridylation and degradation.Nat Commun 12(1):3878. | 2021 | その他 | |
| Lin MJ, et al.(2021) An Insulin-like Growth Factor-1 Conjugated Bombyx mori Silk Fibroin Film for Diabetic Wound Healing: Fabrication, Physicochemical Property Characterization, and and Dosage Optimization In Vitro and In Vivo.Pharmaceutics 13(9): 1459. | 2021 | 薬剤機構 | |
| Lin YK, et al.(2021) Pterostilbene Increases LDL Metabolism in HL-1 Cardiomyocytes by Modulating the PCSK9/HNF1α/SREBP2/LDLR Signaling Cascade, Upregulating Epigenetic hsa-miR-335 and hsa-miR-6825, and LDL Receptor Expression.Antioxidants 10(8):1280. | 2021 | 細胞シグナル伝達 | |
| Lin YM, et al.(2021) Small Molecule Compound Nerolidol attenuates Hypertension induced hypertrophy in spontaneously hypertensive rats through modulation of Mel-18-IGF-IIR signaling.Phytomedicine Jan 4 doi: 10.1016/j.phymed.2020.153450 | 2021 | その他 | |
| Lipońska A, MNF Yap.(2021) Hibernation-Promoting Factor Sequesters Staphylococcus aureus Ribosomes to Antagonize RNase R-Mediated Nucleolytic Degradation. mBio Jul 13 doi: 10.1128/mBio.00334-21. | 2021 | 微生物およびモデル生物 | |
| Liu C, et al.(2021) Epigallocatechin gallate (EGCG) attenuates staphylococcal alpha-hemolysin (Hla)-induced NLRP3 inflammasome activation via ROS-MAPK pathways and EGCG-Hla interactions.Int Immunopharmacol 100:108170. | 2021 | 微生物およびモデル生物 | |
| Liu C, et al.(2021) The Downregulation of Placental Lumican Promotes the Progression of Preeclampsia.Reprod Sci Jul 6 doi: 10.1007/s43032-021-00660-w. | 2021 | その他 | |
| Liu D, et al.(2021) The mRNA Tether Model for Activation-Induced Deaminase and its Relevance for Ig Somatic Hypermutation and Class Switch Recombination.DNA Repair (Amst) 110:103271. | 2021 | DNA修復 | |
| Liu Y, et al.(2021) Long noncoding RNA MIR22HG promotes Leydig cell apoptosis by acting as a competing endogenous RNA for microRNA-125a-5p that targets N-Myc downstream-regulated gene 2 in late-onset hypogonadism.Lab Invest Aug 26 doi: 10.1038/s41374-021-00645-y. | 2021 | 細胞シグナル伝達 | |
| Liu Y, et al.(2021) microRNA-221 upregulates the expression of P-gp and Bcl-2 by activating the Stat3 pathway to promote doxorubicin resistance in osteosarcoma cells. | 2021 | 細胞シグナル伝達 | |
| Loeven NA, et al.(2021) The Burkholderia cenocepacia Type VI Secretion System Effector TecA Is a Virulence Factor in Mouse Models of Lung Infection. mBio Sep 28 doi: 10.1128/mBio.02098-21. | 2021 | 微生物およびモデル生物 | |
| Londoño PAC, et al.(2021) Is mRNA decapping by ApaH like phosphatases present in eukaryotes beyond the Kinetoplastida? BMC Ecol Evol 21(1):131. | 2021 | その他 | |
| Lu L, et al.(2021) Therapeutic Effects of Sodium Para-Aminosalicylic Acid on Cognitive Deficits and Activated ERK1/2-p90RSK/NF-κB Inflammatory Pathway in Pb-Exposed Rats.Biol Trace Elem Res Aug 16 doi: 10.1007/s12011-021-02874-0. | 2021 | 神経生物学 | |
| Lu Z, et al.(2021) PP2A protects podocytes against Adriamycin-induced injury and epithelial-to-mesenchymal transition via suppressing JIP4/p38-MAPK pathway.Cytotechnology Aug 13 doi: 10.1007/s10616-021-00484-1. | 2021 | 細胞シグナル伝達 | |
| Martire A, et al.(2021) P2X7 Receptor Agonist 2′(3′)-O-(4-Benzoylbenzoyl) ATP Differently Modulates Cell Viability and Corticostriatal Synaptic Transmission in Experimental Models of Huntington’s Disease.Front Pharmacol Feb 19 doi: 10.3389/fphar.2020.633861. | 2021 | 神経生物学 | |
| Meng J, et al.(2021) MiR-15a-5p targets FOSL1 to inhibit proliferation and promote apoptosis of keratinocytes via MAPK/ERK pathway.J Tissue Viability Sept 1 doi: 10.1016/j.jtv.2021.08.006. | 2021 | 細胞シグナル伝達 | |
| Miyake T, et al.(2021) Nucleolar localization of c-Jun. FEBS J Sep 9 doi: 10.1111/febs.16187. | 2021 | 構造生物学／タンパク質相互作用 | |
| MOHIUDDIN MD, et al.(2021) Cisplatin Activates the Growth Inhibitory Signaling Pathways by Enhancing the Production of Reactive Oxygen Species in Non-small Cell Lung Cancer Carrying an an EGFR Exon 19 Deletion.Cancer Genomics Proteomics 18(3 Suppl):471-486 | 2021 | がん研究 | 肺がん |
| Mohiuddin MD, et al.(2021) Cisplatin and Pemetrexed Have Distinctive Growth-inhibitory Effects in Monotherapy and Combination Therapy on KRAS-dependent A549 Lung Cancer Cells.Cancer Genomics Proteomics 18(4):579-590. | 2021 | がん研究 | 肺がん |
| Mohiuddin MD, et al.(2021) Paclitaxel Impedes EGFR-mutated PC9 Cell Growth via Reactive Oxygen Species-mediated DNA Damage and EGFR/PI3K/AKT/mTOR Signaling Pathway Suppression.Cancer Genomics Proteomics 18(5):645-659. | 2021 | 細胞シグナル伝達 | |
| Mohiuddin MD, et al.(2021) The Mechanisms of the Growth Inhibitory Effects of Paclitaxel on Gefitinib-resistant Non-small Cell Lung Cancer Cells.Cancer Genomics Proteomics 18(5):661-673. | 2021 | がん研究 | 肺がん |
| Munis AM, et al.(2021) RNA-Seq Analysis of the Human Surfactant Air-Liquid Interface Culture Reveals Alveolar Type II Cell-like Transcriptome.Mol Ther Methods Clin Dev Nov 24 doi: 10.1016/j.omtm.2021.11.06. | 2021 | その他 | |
| Murata K, et al.(2021) Efficient induction of proximity-dependent labeling by biotin feeding in BMAL1-BioID knock-in mice.J Biochem May 12 doi: 10.1093/jb/mvab059 | 2021 | メソッド開発 | |
| Nabar NR, et al.(2021) LRRK2 is required for CD38-mediated NAADP-Ca2+ signaling and the downstream activation of TFEB (transcription factor EB) in immune cells.Autophagy Jul 27 doi: 10.1080/15548627.2021.1954779. | 2021 | 細胞シグナル伝達 | |
| Nagae F, et al.(2021) The lane-switch mechanism for nucleosome repositioning by DNA translocase.Nucleic Acids Res Aug 7 doi: 10.1093/nar/gkab664. | 2021 | 構造生物学とタンパク質相互作用 | |
| Nakase I, et al.(2021) Environmental pH stress influences cellular secretion and uptake of extracellular vesicles.FEBS Open Bio Feb 3 doi: 10.1002/2211-5463.13107. | 2021 | その他 | |
| Negatu DA, et al.(2021) Piperidine-4-carboxamides target DNA gyrase in Mycobacterium abscessus.Antimicrob Agents Chemother May 17 doi: 10.1128/AAC.00676-21. | 2021 | 微生物およびモデル生物 | |
| Nelson JW, et al.(2021) The gut microbiome contributes to blood‐brain barrier disruption in spontaneously hypertensive stroke prone rats.FASEB J 35(2):e21201. | 2021 | 微生物およびモデル生物 | |
| Niyonizigiye I, et al.(2021) Aspilia africana CD Adams inhibits the production of lipopolysaccharide-induced inflammatory mediators in murine macrophage RAW264.7 cells by suppressing the NF-κB and PI3K/Akt pathways.S Afr J Bot 141: 83–89 | 2021 | 植物科学 | |
| Nußbaum P, et al.(2021) The archaeal protein SepF is essential for cell division in Haloferax volcanii.Nat Commun 12(1):3469. | 2021 | 微生物およびモデル生物 | |
| Okazawa M, et al.(2021) A 3-styrylchromone converted from trimebutine 3D pharmacophore possesses dual suppressive effects on RAGE and TLR4 signaling pathways.Biochem Biophys Res Commun 566:1-8. | 2021 | 細胞シグナル伝達 | |
| Oyama T, et al.(2021) Hinokitiol-induced decreases of tyrosinase and microphthalmia-associated transcription factor are mediated by the endoplasmic reticulum-associated degradation pathway in human melanoma cells.Biochimie Sep 15 doi: 10.1016/j.biochi.2021.09.007. | 2021 | がん研究 | 皮膚がん |
| Parashar P, et al.(2021) Targeted biologic inhibition of both tumor cell-intrinsic and intercellular CLPTM1L/CRR9 mediated chemotherapeutic drug resistance.NPJ Precis Oncol 5(1):16. | 2021 | がん研究 | 卵巣がん |
| Park SK, et al.(2021) Ecklonia cava Attenuates PM2.5-Induced Cognitive Decline through Mitochondrial Activation and Anti-Inflammatory Effect.Mar Drugs 19(3):131. | 2021 | 神経生物学 | |
| Pastuschek J, et al.(2021) Molecular characteristics of established trophoblast-derived cell lines.Placenta Mar 4 doi: 10.1016/j.placenta.2021.02.022. | 2021 | その他 | |
| Pourfarjam Y, et al.(2021) Structural and biochemical analysis of human ADP-ribosyl-acceptor hydrolase 3 (ARH3) reveals the basis of metal selectivity and different roles for the two Mg ions.J Biol Chem Apr 21 doi: 10.1016/j.jbc.2021.100692 | 2021 | 構造生物学／タンパク質相互作用 | |
| Purves TD, et al.(2021) Reductions in midbrain GABAergic and dopamine neuron markers are linked in schizophrenia.Mol Brain 14(1):96. | 2021 | 神経生物学 | |
| Qadeer A, et al.(2021) Transcriptional profiles of genes potentially involved in extracellular vesicle biogenesis in Schistosoma japonicum.Acta Trop 217:105851. | 2021 | その他 | |
| Qin D, et al.(2021) LINC01207 promotes prostate cancer progression by sponging miR‑1182 to upregulate AKT3.Oncology Letters Dec 21 doi: 10.3892/ol.2021.13175. | 2021 | がん研究 | 一般 |
| Qiu H, et al.(2021) miR-30b-5p inhibits cancer progression and enhances cisplatin sensitivity in lung cancer through targeting LRP8.Apoptosis Mar 29 doi: 10.1007/s10495-021-01665-1. | 2021 | がん研究 | 肺がん |
| Qiu X, et al.(2021) Forkhead box O1 targeting replication factor C subunit 2 expression promotes glioma temozolomide resistance and survival.Ann Transl Med (8):692 | 2021 | がん研究 | 脳腫瘍 |
| Qiu Y, et al.(2021) RNA binding protein MEX3A controls G1/S transition via regulating the RB/E2F pathway in clear cell renal cell carcinoma.Mol Ther Nucleic Acids 27:241-255 | 2021 | がん研究 | 一般 |
| Radhakrishnan K, et al.(2021) Orphan nuclear receptor ERR-γ regulates hepatic FGF23 production in acute kidney injury.Proc Natl Acad Sci USA 118(16):e2022841118. | 2021 | その他 | |
| Rao Y, et al.(2021) NeuroD1 induces microglial apoptosis and cannot induce microglia-to-neuron cross-lineage reprogramming.Neuron doi: 10.1016/j.neuron.2021.11.008. | 2021 | 神経生物学 | |
| Ratti S, et al.(2021) Lamin B1 Accumulation's Effects on Autosomal Dominant Leukodystrophy (ADLD): Induction of Reactivity in the Astrocytes.Cells 10(10):2566. | 2021 | 神経生物学 | |
| Rehnitz J, et al.(2021) FMR1 expression in human granulosa cells and variable ovarian response: control by epigenetic mechanisms.Mol Hum Reprod Jan 25 doi: 10.1093/molehr/gaab001. | 2021 | その他 | |
| Rensi N, et al.(2021) Evaluation of TFR-1 Expression in Feline Mammary Cancer and In Vitro Antitumor Efficacy Study of Doxorubicin-Loaded H-Ferritin Nanocages.Cancers 13(6): 1248. | 2021 | がん研究 | 乳がん |
| Roberts A, et al.(2021) Electroactive reduced graphene oxide for highly sensitive detection of secretory non-structural 1 protein: A potential diagnostic biomarker for Japanese encephalitis virus.Biosens Bioelectron 198:113837. | 2021 | 疾病研究 | バイオマーカー研究 |
| Rodriguez F, et al.(2021) Surveillance of Trypanosoma cruzi infection in Triatomine vectors, feral dogs and cats, and wild animals in and around El Paso county, Texas, and New Mexico.PLoS Negl Trop Dis 15(2):e0009147. | 2021 | 微生物およびモデル生物 | |
| Russell JC, et al.(2021) Generation and characterization of a tractable C. elegans model of tauopathy.Geroscience Sep 18 doi: 10.1007/s11357-021-00436-9. | 2021 | 神経生物学 | |
| Ryota C. et al.(2021) Divergence in chondrogenic potential between in vitro and in vivo of adipose-and synovial-stem cells from mouse and human.Stem Cell Res Ther 12(1):405. | 2021 | 幹細胞 | |
| Santerre M, et al.(2021) HIV-1 Vpr protein impairs lysosome clearance causing SNCA/alpha-synuclein accumulation in neurons.Autophagy Apr 23 doi: 10.1080/15548627.2021.1915641. | 2021 | 神経生物学 | |
| Santos MF, et al.(2021) Itraconazole inhibits nuclear delivery of extracellular vesicle cargo by disrupting the entry of late endosomes into the nucleoplasmic reticulum.J Extracell Vesicles 10(10):e12132. | 2021 | その他 | |
| Savitr C, et al.(2021) M2 Macrophage-Derived Concentrated Conditioned Media Significantly Improves Skin Wound Healing.Tissue Eng Regen Med Dec 28. doi: 10.1007/s13770-021-00414-4. | 2021 | その他 | |
| Senji Laxme RR, et al.(2021) Biogeographical venom variation in the Indian spectacled cobra (Naja naja) underscores the pressing need for pan-India efficacious snakebite therapy.PLoS Negl Trop Dis 15(2):e0009150. | 2021 | その他 | |
| Seno S, et al.(2021) β-Thujaplicin Enhances TRAIL-Induced Apoptosis via the Dual Effects of XIAP Inhibition and Degradation in NCI-H460 Human Lung Cancer Cells.Medicines 8(6):26. | 2021 | がん研究 | 肺がん |
| Shih HJ, et al.(2021) Differential expression of hypoxia-inducible factors related to the invasiveness of epithelial ovarian cancer.Sci Rep 11(1):22925. | 2021 | がん研究 | 一般 |
| Shih HJ, et al.(2021) Simultaneous Inhibition of Three Major Cytokines and Its Therapeutic Effects: A Peptide-Based Novel Therapy against Endotoxemia in Mice.J Pers Med 11(5): 436. | 2021 | 薬剤機構 | |
| Shirsath K, et al.(2021) Chronic photoperiodic manipulation induced chronodisruption upregulates HSP60 during early pro-atherogenic remodeling in thoracic aorta of C57BL/6J mice.The Journal of Basic and Applied Zoology 82:9. | 2021 | その他 | |
| Shirsath K, et al.(2021) HSP60 knockdown exerts differential response in endothelial cells and monocyte derived macrophages during atherogenic transformation.Sci Rep 11(1):1086. | 2021 | その他 | |
| Siwach M, et al.(2021) An organelle-tethering mechanism couples flagellation to cell division in bacteria.Dev Cell Feb 17 doi: 10.1016/j.devcel.2021.01.013. | 2021 | 微生物およびモデル生物 | |
| Skertich NJ, et al.(2021) Expression of Programmed Death Ligand 1 in Drug Resistant Osteosarcoma: An Exploratory Study.Surg Open Sci doi: 10.1016/j.sopen.2021.07.001. | 2021 | がん研究 | 一般 |
| Slominski AT, et al.(2021) Vitamin D and lumisterol derivatives can act on liver X receptors (LXRs).Sci Rep 11(1):8002. | 2021 | その他 | |
| Souza COS, et al.(2021) NLRC4 inhibits NLRP3 inflammasome and abrogates effective antifungal CD8+ T cell responses. iScience May 18 doi.org/10.1016/j.isci.2021.102548 | 2021 | その他 | |
| Spampinato S, et al.(2021) Protective effect of the sphingosine-1 phosphate receptor agonist siponimod on disrupted blood brain barrier function.Biochem Pharmacol 186:114465. | 2021 | 神経生物学 | |
| Srinivasan A, et al.(2021) Preclinical Development of Plant‐based Oral Immune Modulatory Therapy for Hemophilia B. Plant Biotechnol J May 5 doi: 10.1111/pbi.13608 | 2021 | その他 | |
| Sripathi SR, et al.(2021) Epithelial to mesenchymal transition (EMT) of human stem cell-derived retinal pigment epithelium shares commonalities with malignancy-associated EMT: a proteomic analysis.Mol Cell Proteomics Aug 26 doi: 10.1016/j.mcpro.2021.100131. | 2021 | 幹細胞 | |
| Srivastava T, et al.(2021) A mouse model of prenatal exposure to Interleukin-6 to study the developmental origin of health and disease.Sci Rep 11(1):13260. | 2021 | その他 | |
| Stabel JR, et al.(2021) Reduced tissue colonization of Mycobacterium avium subsp. paratuberculosis in neonatal calves vaccinated with a cocktail of recombinant proteins.Vaccine 39(23):3131–3140 | 2021 | その他 | |
| Su N , et al.(2021) Circ_0001666 affects miR-620/WNK2 axis to inhibit breast cancer progression.Genes Genomics Jun 1 doi: 10.1007/s13258-021-01114-y | 2021 | がん研究 | 乳がん |
| Sun L, et al.(2021) Electroacupuncture ameliorates postoperative cognitive dysfunction and associated neuroinflammation via NLRP3 signal inhibition in aged mice.CNS Neurosci Ther Dec 23. doi: 10.1111/cns.13784. | 2021 | 神経生物学 | |
| Sunagar K, et al.(2021) A Wolf in Another Wolf's Clothing: Post-Genomic Regulation Dictates Venom Profiles of Medically-Important Cryptic Kraits in India.Toxins (Basel) 13(1):69. | 2021 | その他 | |
| Suthon S, et al.(2021) Estrogen receptor alpha and NFATc1 bind to a bone mineral density-associated SNP to repress WNT5B in osteoblasts.Am J Hum Genet Dec 2 doi: 10.1016/j.ajhg.2021.11.018. | 2021 | 疾病研究 | バイオマーカー研究 |
| Suzuki Y, et al.(2021) Pathogenicity and genomic features of vapN-harboring Rhodococcus equi isolated from human patients.Int J Med Microbiol July 2 doi: 10.1016/j.ijmm.2021.151519. | 2021 | その他 | |
| Switzer CH, et al.(2021) Cysteine trisulfide oxidizes protein thiols and induces electrophilic stress in human cells.Redox Biol 47:102155. | 2021 | 細胞シグナル伝達 | |
| Szatmári Á, et al.(2021) A pattern-triggered immunity-related phenolic, acetosyringone, boosts rapid inhibition of a diverse set of plant pathogenic bacteria.BMC Plant Biol 21(1):153. | 2021 | 植物科学 | |
| Tada T, et al.(2021) Convalescent-Phase Sera and Vaccine-Elicited Antibodies Largely Maintain Neutralizing Titer against Global SARS-CoV-2 Variant Spikes. mBio Jun 1 doi: 10.1128/mBio.00696-21. | 2021 | その他 | |
| Takahashi M, et al.(2021) Quick and Easy Assembly of a One-Step qRT-PCR Kit for COVID-19 Diagnostics Using In-House Enzymes.ACS Omega 6(11): 7374–7386. | 2021 | メソッド開発 | |
| Takahashi Y, et al.(2021) Direct administration of the non-competitive interleukin-1 receptor antagonist rytvela transiently reduced intrauterine inflammation in an extremely preterm sheep model of chorioamnionitis.PLoS One 16(9):e0257847. | 2021 | その他 | |
| Tanaka H, et al.(2021) Human colorectal cancer-associated carbohydrate antigen on annexin A2 protein.J Mol Med (Berl) Apr 27 doi: 10.1007/s00109-021-02077-z | 2021 | がん研究 | 大腸がん |
| Tang M, et al.(2021) Glycyrrhetinic acid remodels the tumor microenvironment and synergizes with doxorubicin for breast cancer treatment in a murine model.Nanotechnology Jan 27. doi: 10.1088/1361-6528/abe076. | 2021 | がん研究 | 乳がん |
| Taş İ, et al.(2021) Physciosporin Suppresses Mitochondrial Respiration, Aerobic Glycolysis, and Tumorigenesis in Breast Cancer.Phytomedicine Jul 18 doi: 10.1016/j.phymed.2021.153674. | 2021 | がん研究 | 乳がん |
| Tassone A, et al.(2021) Vesicular Acetylcholine Transporter Alters Cholinergic Tone and Synaptic Plasticity in DYT1 Dystonia.Mov Disord Jun 26 doi: 10.1002/mds.28698 | 2021 | 神経生物学 | |
| Teti G, et al.(2021) Cellular senescence in vascular wall mesenchymal stromal cells, a possible contribution to the development of aortic aneurysm.Mech Ageing Dev 197:111515. | 2021 | その他 | |
| Tong X, et al.(2021) RNF144A-AS1 promotes the development of glioma cells by targeting miR-665/HMGA1 axis.Neurosci Lett Sep 21 doi: 10.1016/j.neulet.2021.136259. | 2021 | がん研究 | 一般 |
| Toychiev AH, et al.(2021) Gap Junctional Coupling Between Retinal Astrocytes Exacerbates Neuronal Damage in Ischemia-Reperfusion Injury.Invest Ophthalmol Vis Sci 62(14):27. | 2021 | 神経生物学 | |
| Ueda H, et al.(2021) Synthesis of sp [3]-Rich Chiral Bicyclo [3.3.1] nonanes for Chemical Space Expansion and Study of Biological Activities.Bioorg Med Chem 54:116561. | 2021 | その他 | |
| Urrutia Iñiguez J, et al.(2021) An epilepsy-causing mutation leads to co-translational misfolding of the Kv7.2 channel.BMC Biol 19(1):109. | 2021 | 神経生物学 | |
| V Kumar, et al.(2021) Polymeric nanomedicine for overcoming resistance mechanisms in hedgehog and Myc-amplified medulloblastoma.Biomaterials 278:121138. | 2021 | 薬剤機構 | |
| Vakilian S, et al.(2021) An engineered microfluidic blood‐brain barrier model to evaluate the anti‐metastatic activity of β‐boswellic acid.Biotechnol J Jul 27 doi: 10.1002/biot.202100044 | 2021 | がん研究 | 一般 |
| Valenzuela-Muñoz V, et al.(2021) Transcriptome and morphological analysis in Caligus rogercresseyi uncover the effects of Atlantic salmon vaccination with IPath®. | 2021 | その他 | |
| Vester SK, et al.(2021) Nucleolin acts as the receptor for C1QTNF4 and supports C1QTNF4-mediated innate immunity modulation.J Biol Chem Mar 4 doi: 10.1016/j.jbc.2021.100513. | 2021 | 構造生物学／タンパク質相互作用 | |
| Wan S, et al.(2021) MicroRNA-140-3p represses the proliferation, migration, invasion and angiogenesis of lung adenocarcinoma cells via targeting TYMS (Thymidylate Synthetase).Bioengineered Nov 24 doi: 10.1080/21655979.2021.2009422 | 2021 | がん研究 | 肺がん |
| Wang J, et al.(2021) MicroRNA-532-5p upregulation protects neurological deficits after ischemic stroke through inhibition of BTB and CNC homology 1.Int Immunopharmacol 100:108003. | 2021 | 神経生物学 | |
| Wang K, et al.(2021) Downregulation of DEAD-box helicase 21 (DDX21) inhibits proliferation, cell cycle, and tumor growth in colorectal cancer via targeting cell division cycle 5-like (CDC5L).Bioengineered 12(2):12647-12658. | 2021 | がん研究 | 大腸がん |
| Wang P, et al.(2021) Loss of haspin suppresses cancer cell proliferation by interfering with cell cycle progression at multiple stages.FASEB J 35(10):e21923. | 2021 | がん研究 | 一般 |
| Wang X, et al.(2021) Staphylococcus aureus Extracellular Vesicles: A Story of Toxicity and the Stress of 2020.Toxins (Basel) 13(2):E75. | 2021 | 微生物およびモデル生物 | |
| Wang Y, et al.(2021) MYPT1, regulated by miR-19b-3p inhibits the progression of non-small cell lung cancer via inhibiting the activation of wnt/β-catenin signaling.Life Sci May 5 doi: 10.1016/j.lfs.2021.119573 | 2021 | がん研究 | 肺がん |
| Wei, Y et al.(2021) Acacetin ameliorates insulin resistance in obesity mice through regulating Treg/Th17 balance via MiR-23b-3p/NEU1 Axis.BMC Endocr Disord 21(1):57. | 2021 | 細胞シグナル伝達 | |
| Welch JL, et al.(2021) Human T cells express Angiotensin Converting Enzyme 2 at levels sufficient to interact with the SARS-CoV-2 Spike protein.J Infect Dis Dec 16 doi: 10.1093/infdis/jiab595. | 2021 | 微生物およびモデル生物 | |
| Wen L, et al.(2021) The lignan sesamin suppresses TRIM44 and exerts antitumor activity to esophageal squamous cell carcinoma.Chem Biol Drug Des Aug 19. doi: 10.1111/cbdd.13937. | 2021 | がん研究 | 扁平上皮がん |
| Wu CL, et al.(2021) Single cell transcriptomic analysis of human pluripotent stem cell chondrogenesis.Nat Commun 12(1):362. | 2021 | 幹細胞 | |
| Xu J, et al.(2021) Oxidative stress induced by NOX2 contributes to neuropathic pain via plasma membrane translocation of PKCε in rat dorsal root ganglion neurons.J Neuroinflammation 18(1):106 | 2021 | 神経生物学 | |
| Yahya G, et al.(2021) Profiling the physiological pitfalls of anti‐hepatitis C direct‐acting agents in budding yeast.Microb Biotechnol Aug 11 doi: 10.1111/1751-7915.13904. | 2021 | 微生物およびモデル生物 | |
| Yan L, et al.(2021) Fisetin ameliorates atherosclerosis by regulating PCSK9 and LOX‑1 in apoE‑/‑mice.Exp Ther Med 21:25. | 2021 | 薬剤機構 | |
| Yang C, et al.(2021) Nuclear IGF1R interacts with NuMA and regulates 53BP1‑dependent DNA double‑strand break repair in colorectal cancer.Oncol Rep 46(2):168. | 2021 | がん研究 | 大腸がん |
| Yang W, et al.(2021) Maresin 1 protects against lipopolysaccharide/d-galactosamine-induced acute liver injury by inhibiting macrophage pyroptosis and inflammatory response.Biochem Pharmacol 195:114863. | 2021 | その他 | |
| Yang X, et al.(2021) Identification and verification of HCAR3 and INSL5 as new potential therapeutic targets of colorectal cancer.World J Surg Oncol 19(1):248. | 2021 | がん研究 | 大腸がん |
| Yang Y, et al.(2021) Dysregulated APP expression and α-secretase processing of APP is involved in manganese-induced cognitive impairment.Ecotoxicol Environ Saf 220:112365. | 2021 | その他 | |
| Yankel C, et al.(2020) Visualizing the dynamics of exported bacterial proteins with the chemogenetic fluorescent reporter FAST.Sci Rep 10(1):15791. | 2021 | メソッド開発 | |
| Yazgili AS, et al.(2021) In-gel proteasome assay to determine the activity, amount, and composition of proteasome complexes from mammalian cells or tissues.STAR Protoc 2(2): 100526 | 2021 | メソッド開発 | |
| Yeini E, et al.(2021) P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression.Nat Commun 12(1):1912. | 2021 | がん研究 | 脳腫瘍 |
| Yi H, et al.(2021) Knockdown of long non‑coding RNA DLEU2 suppresses idiopathic pulmonary fibrosis by regulating the microRNA‑369‑3p/TRIM2 axis.Int J Mol Med 47(5):80. | 2021 | その他 | |
| Yoo SK, et al.(2021) Immature Persimmon Suppresses Amyloid Beta (Aβ) Mediated Cognitive Dysfunction via Tau Pathology in ICR Mice.Curr Issues Mol Biol 43(1):405-422. | 2021 | 神経生物学 | |
| Young N, et al.(2021) Biallelic SYNE2 Missense Mutations Leading to Nesprin-2 Giant Hypo-Expression Are Associated with Intellectual Disability and Autism.Genes 12(9): 1294. | 2021 | 神経生物学 | |
| Yousefzadeh MJ, et al.(2021) An aged immune system drives senescence and ageing of solid organs.Nature May 12 doi: 10.1038/s41586-021-03547-7 | 2021 | その他 | |
| Yu C, et al.(2021) Protective Effect and Mechanism of Schisandra Chinensis Extract on Retinal Photoreceptor Cell Injury.Farmacia 69(1): 107-112. | 2021 | その他 | |
| Yu S, et al.(2021) A Protein from Dioscorea polystachya (Chinese Yam) Improves Hydrocortisone-Induced Testicular Dysfunction by Alleviating Leydig Cell Injury via Upregulation of the Nrf2 Pathway.Oxid Med Cell Longev 2021:3575016 | 2021 | 細胞シグナル伝達 | |
| Yu Y, et al.(2021) Prodrug Nanomedicine Inhibits Chemotherapy-Induced Proliferative Burst by Altering the Deleterious Intercellular Communication.ACS Nano Jan 7 doi: 10.1021/acsnano.0c07113. | 2021 | がん研究 | 一般 |
| Yuk H, et al.(2021) Necrostatin-1 Prevents Ferroptosis in a RIPK1-and IDO-Independent Manner in Hepatocellular Carcinoma.Antioxidants 10(9): 1347. | 2021 | がん研究 | 肝臓がん |
| Zabegina L, et al.(2021) A New Approach for Prostate Cancer Diagnosis by miRNA Profiling of Prostate-Derived Plasma Small Extracellular Vesicles.Cells 10(9): 2372. | 2021 | がん研究 | 一般 |
| Zhai L, et al.(2021) Overexpressed Versican Promoted Cell Multiplication, Migration and Invasion in Gastric Cancer.Tissue Cell 73:101611. | 2021 | がん研究 | 胃がん |
| Zhang L, et al.(2021) MiR-22 regulated T cell differentiation and hepatocellular carcinoma growth by directly targeting Jarid2.Am J Cancer Res 11(5):2159-2173. | 2021 | がん研究 | 肝臓がん |
| Zhang M, et al.(2021) Optimized photochemistry enables efficient analysis of dynamic RNA structuromes and interactomes in genetic and infectious diseases.Nat Commun 12(1):2344. | 2021 | その他 | |
| Zhang X, et la. (2021) Transcranial photobiomodulation therapy ameliorates perioperative neurocognitive disorder through modulation of mitochondrial function in aged mice.Neuroscience Dec 31 doi: 10.1016/j.neuroscience.2021.12.033. | 2021 | 神経生物学 | |
| Zhang Y, et al.(2021) Cerebellar Kv3.3 potassium channels activate TANK-binding kinase 1 to regulate trafficking of the cell survival protein Hax-1.Nat Commun 12(1):1731 | 2021 | 細胞シグナル伝達 | |
| Zhang Y, et al.(2021) Lycium barbarum Polysaccharides Promotes Mitochondrial Biogenesis and Energy Balance in a NAFLD Cell Model.Chin J Integr Med Dec 7 doi: 10.1007/s11655-021-3309-6. | 2021 | Mitochondrial studies | |
| Zhang Y, et al.(2021) Overexpression of miR-99a Alleviates Intestinal Mucosal Barrier Injury in Rats with Severe Acute Pancreatitis.J Interferon Cytokine Res 41(2):72-80. | 2021 | その他 | |
| Zhang YY, et al.(2021) Chimeric antigen-guiding extracellular vesicles eliminate antigen-specific Th2 cells in subjects with food allergy.World Allergy Organ J 14(3): 100522. | 2021 | その他 | |
| Zhao Y, et al.(2021) Inhibiting USP14 ameliorates inflammatory responses in trophoblast cells by suppressing MAPK/NF‐κB signaling.Immun Inflamm Dis Jun 5 doi: 10.1002/iid3.465. | 2021 | 細胞シグナル伝達 | |
| Zhou X, et al.(2021) UTMD-mediated delivery of MiR-21-5p inhibitor suppresses the development of lung cancer.Tissue Cell 74:101719. | 2021 | がん研究 | 肺がん |
| Zhu J, et al.(2021) Predictive Models for HCC Prognosis, Recurrence Risk, and Immune Infiltration Based on Two Exosomal Genes: MYL6B and THOC2.J Inflamm Res 14:4089-4109. | 2021 | がん研究 | 肝臓がん |
| Zimmer A, et al.(2021) Thioredoxin system activation is associated with the progression of experimental pulmonary arterial hypertension.Life Sci 284:119917. | 2021 | 細胞シグナル伝達 | |
| Adhikari A and Davie JK (2020) The PRC2 complex directly regulates the cell cycle and controls proliferation in skeletal muscle.Cell Cycle Aug 20 doi: 10.1080/15384101.2020.1806448. | 2020 | その他 | |
| Adhikari XY, et al.(2020) IFN-γ and CIITA modulate IL-6 expression in skeletal muscle.Cytokine: X (2)2:100023 | 2020 | その他 | |
| Ali G, et al.(2020) Keratinocytes derived from patient-specific induced pluripotent stem cells recapitulate the genetic signature of psoriasis disease.Stem Cells Dev Jan 29 doi: 10.1089/scd.2019.0150. | 2020 | 疾病研究：バイオマーカー研究 | |
| Almacellas E, et al.(2020) Lysosomal degradation ensures accurate chromosomal segregation to prevent chromosomal instability.Autophagy Jun 23 doi: 10.1080/15548627.2020.1764727. | 2020 | その他 | |
| An N, et al.(2020) SEZ6L2 Knockdown Impairs Tumour Growth by Promoting Caspase-Dependent Apoptosis in Colorectal Cancer.J Cell Mol Med Feb 27 doi: 10.1111/jcmm.15082. | 2020 | 細胞シグナル伝達 | |
| Arreal L, et al.(2020) Targeting PML in Triple Negative Breast Cancer Elicits Growth Suppression and Senescence.Cell Death Differ 27:1186–1199. | 2020 | がん | 乳房 |
| Barilli A, et al.(2020) Organic Cation Transporters (OCTs) in EpiAirway™, A Cellular Model of Normal Human Bronchial Epithelium.Biomedicines 8(5):127. | 2020 | その他 | |
| Bartish M, et al.(2020) MNK2 governs the macrophage antiinflammatory phenotype.Proc Natl Acad Sci U S A Oct 19 doi: 10.1073/pnas.1920377117. | 2020 | 細胞シグナル伝達 | |
| Baxter K, et al.(2020) Towards defining global ecotypes of the toxic cyanobacterium Raphidiopsis raciborskii.Applied Phycology Aug 6 doi: 10.1080/26388081.2020.1740891. | 2020 | 微生物およびモデル生物 | |
| Bayazid AB, et al.(2020) Antioxidant, Anti-inflammatory, and Antiproliferative Activity of Mori Cortex Radicis Extracts.Natural Prod Comm 15(1):1–8. | 2020 | その他 | |
| Bhattacharjee P, et al.(2020) Synthetic Carboline Compounds Targeting Protein: Biophysical and Biological Perspective.J Biomol Struct Dyn June 1 doi: 10.1080/07391102.2020.1769732. | 2020 | その他 | |
| Bittmann J, et al.(2020) An Advanced Cell Cycle Tag Toolbox Reveals Principles Underlying Temporal Control of Structure-Selective Nucleases.Elife 9:e52459. | 2020 | その他 | |
| Bonar MM, et al.(2020) Nanoscale flow cytometry reveals interpatient variability in HIV protease activity that correlates with viral infectivity and identifies drug-resistant viruses.Sci Rep 10(1):18101. | 2020 | メソッド開発 | |
| Bouza AA, et al.(2020) Sodium channel β1 subunits are post-translationally modified by tyrosine phosphorylation, S-palmitoylation, and regulated intramembrane proteolysis.J Biol Chem 295(30):10380–10393. | 2020 | その他 | |
| Chen D, et al.(2020) Cancer Cell Membrane-Decorated Zeolitic-Imidazolate Frameworks Codelivering Cisplatin and Oleanolic Acid Induce Apoptosis and Reversed Multidrug Resistance on Bladder Carcinoma Cells.ACS Omega 5(2):995-1002. | 2020 | がん | 膀胱 |
| Chen D, et al.(2020) Downregulating miR-96-5p promotes proliferation, migration, and invasion, and inhibits apoptosis in human trophoblast cells via targeting DDAH1.Reprod BioI 21(1):100474. | 2020 | 細胞シグナル伝達 | |
| Chen Q, et al.(2020) Angiocrine Sphingosine-1-Phosphate Activation of S1PR2-YAP Signaling Axis in Alveolar Type II Cells Is Essential for Lung Repair.Cell Rep 31(13):107828. | 2020 | その他 | |
| Cheng L, et al.(2020) Exercise Promotes the Osteoinduction of HA/β-TCP Biomaterials via the Wnt Signaling Pathway.Metabolites 10(3):E90. | 2020 | 細胞シグナル伝達 | |
| Ciu S, et al.(2020) LncRNA MAGI2-AS3 is down-regulated in intervertebral disc degeneration and participates in the regulation of FasL expression in nucleus pulposus cells.BMC Musculoskelet Disord 21:149. | 2020 | その他 | |
| Darvish-Ghane S, et al.(2020) D1 receptors in the anterior cingulate cortex modulate basal mechanical sensitivity threshold and glutamatergic synaptic transmission.Mol Brain 13(1):121. | 2020 | 神経生物学 | |
| Darvishi E, et al.(2020) Molecular Mechanisms of Guadecitabine Induced FGFR4 Down Regulation in Alveolar Rhabdomyosarcomas.Neoplasia 22(7):274−282. | 2020 | がん | 一般 |
| de Oliveira BH, et al.(2020) ET-B receptors involvement in peripheral opioid analgesia induced by light-emitting diode photobiomodulation in male and female mice.J Photochem Photobiol B 214:112104. | 2020 | その他 | |
| Delvaux NA, et al.(2020) Fluorescent Labeling of Plasmid DNA for Gene Delivery: Implications of Dye Hydrophobicity on Labeling Efficiencies and Nanoparticle Size.Anal Biochem Aug 9 doi: 10.1016/j.ab.2020.113895. | 2020 | メソッド開発 | |
| Ding Q, et al.(2020) Light-powered Escherichia Coli Cell Division for Chemical Production.Nat Commun 11:2262. | 2020 | 微生物およびモデル生物 | |
| Dopie J, et al.(2020) Tyramide signal amplification mass spectrometry (TSA-MS) ratio identifies nuclear speckle proteins.J Cell Biol 219(9):e201910207. | 2020 | メソッド開発 | |
| Du P, et al.(2020) Chronic stress promotes EMT-mediated metastasis through activation of STAT3 signaling pathway by miR-337-3p in breast cancer.Cell Death Dis 11(9):761. | 2020 | がん研究：乳がん | |
| Dye BK, et al.(2020) Smooth Muscle α-Actin Expression in Mitral Valve Interstitial Cells is Important for Mediating Extracellular Matrix Remodeling.J Cardiovasc Dev Dis 7(3):E32. | 2020 | その他 | |
| Ebelt ND, et al.(2020) 5-Azacytidine Potentiates Anti-tumor Immunity in a Model of Pancreatic Ductal Adenocarcinoma.Front Immunol 11:538. | 2020 | がん | 膵臓 |
| Eccardt AM, et al.(2020) A Peroxidase Mimetic Protects Skeletal Muscle Cells From Peroxide Challenge and Stimulates Insulin Signaling.Am J Physiol Cell Physiol 318(6):C1214−C1225. | 2020 | その他 | |
| Eichler CE, et al.(2020) Compartmentalized oskar degradation in the germ plasm safeguards germline development.Elife 9:e49988. | 2020 | その他 | |
| Elsayed AK, et al.(2020) Derivation of a Human Induced Pluripotent Stem Cell Line (QBRIi007-A) From a Patient Carrying a Homozygous Intronic Mutation (c.613-7T>G) in the SLC2A2 Gene.Stem Cell Res 44:101736. | 2020 | 幹細胞 | |
| Eltai NO, et al.(2020) Antibiotic Resistance and Virulence Patterns of Pathogenic Escherichia Coli Strains Associated With Acute Gastroenteritis Among Children in Qatar.BMC Microbiol 20(1):54. | 2020 | 微生物およびモデル生物 | |
| Esaki M, et al.(2020) The effect of dihydropyrazines on lipopolysaccharide-stimulated human hepatoma HepG2 cells via regulating the TLR4-MyD88-mediated NF-κB signaling pathway.J Toxicol Sci 45(7):401–409. | 2020 | 細胞シグナル伝達 | |
| Fan Q, et al.(2020) Paeoniflorin Modulates Gut Microbial Production of Indole-3-lactate and Epithelial Autophagy to Alleviate Colitis in Mice.Phytomedicine Sept 19 doi: 10.1016/j.phymed.2020.153345 | 2020 | その他 | |
| Foliaki ST, et al.(2020) Pathogenic Prion Protein Isoforms Are Not Present in Cerebral Organoids Generated from Asymptomatic Donors Carrying the E200K Mutation Associated with Familial Prion Disease. | 2020 | 疾病研究：バイオマーカー研究 | |
| Forstner D, et al.(2020) Platelet-derived factors impair placental chorionic gonadotropin beta-subunit synthesis.J Mol Med (Berl) 98(2):193−207. | 2020 | 細胞シグナル伝達 | |
| Francis R, et al.(2020) Glycolytic Inhibitor 2-deoxyglucose Suppresses Inflammatory Response in Innate Immune Cells and Experimental Staphylococcal Endophthalmitis.Exp Eye Res 197:108079. | 2020 | その他 | |
| Furuyama W, et al.(2020) A complement component C1q-mediated mechanism of antibody-dependent enhancement of Ebola virus infection.PLoS Negl Trop Dis 14(9):e0008602. | 2020 | 微生物およびモデル生物 | |
| Fuseya S, et al.(2020) Mice lacking core 1-derived O-glycan in podocytes develop transient proteinuria, resulting in focal segmental glomerulosclerosis.Biochem Biophys Res Comm 523(4):1007−1013. | 2020 | その他 | |
| Gahamanyi N, et al.(2020) Susceptibility of Campylobacter Strains to Selected Natural Products and Frontline Antibiotics.Antibiotics (Basel) 9(11):E790. | 2020 | 微生物およびモデル生物 | |
| Gan C, et al.(2020) Untargeted metabolomics study and pro-apoptotic properties of B-norcholesteryl benzimidazole compounds in ovarian cancer SKOV3 cells.J Steroid Biochem Mol Biol 202:105709. | 2020 | がん研究 | 卵巣 |
| Gibbons GS, et al.(2020) Identification of DOT1L inhibitors by structure-based virtual screening adapted from a nucleoside-focused library.Eur J Med Chem 189:112023. | 2020 | メソッド開発 | |
| Goldstein T, et al.(2020) Spillover of ebolaviruses into people in Eastern Democratic Republic of Congo prior to the 2018 Ebola virus disease outbreak.One Health Outlook 2(1):21. | 2020 | その他 | |
| Guo J, et al.(2020) RNA-binding proteins tristetraprolin and human antigen R are novel modulators of podocyte injury in diabetic kidney disease.Cell Death Dis 11(6):413. | 2020 | その他 | |
| Han HJ, et al.(2020) Anti-Melanogenic Effect of Ethanolic Extract of Sorghum bicolor on IBMX-Induced Melanogenesis in B16/F10 Melanoma Cells.Nutrients 12(3):E832. | 2020 | がん | 皮膚 |
| Han S, et al.(2020) Ultrasound Stimulation Increases Neurite Regeneration in Injured Dorsal Root Ganglion Neurons through Mammalian Target of Rapamycin Activation.Brain Sci 10(7):E409. | 2020 | 細胞シグナル伝達 | |
| Harmouch E, et al.(2020) Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes.Sci Rep 10(1):13750 | 2020 | がん研究 | 脳腫瘍 |
| Hasan ASH, et al.(2020) Characterization of a bicistronic knock-in reporter mouse model for investigating the role of CABLES2 in vivo.Exp Anim Aug 11 doi: 10.1538/expanim.20-0063. | 2020 | 微生物およびモデル生物 | |
| Hashiguchi H, et al.(2020) Glycoproteomic analysis identifies cryptdin-related sequence 1 as O-glycosylated protein modified with α1, 2-fucose in the small intestine.Arch Biochem Biophys 695:108653. | 2020 | 微生物およびモデル生物 | |
| He X, et al.(2020) Hypoxia improved vasculogenesis in distraction osteogenesis through Mesenchymal-Epithelial transition (MET), Wnt/β-catenin signaling pathway, and autophagy.Acta Histochemica 122:151593. | 2020 | 細胞シグナル伝達 | |
| Hong MJ, et al.(2020) Isolation and characterization of kelch repeat-containing F-box proteins from colored wheat.Mol Biol Rep 47(2):1129−1141. | 2020 | 植物科学 | |
| Houston R, et al.(2020) Acetylation-mediated remodeling of the nucleolus regulates cellular acetyl-CoA responses.PLoS Biol 18(11):e3000981. | 2020 | CRISPR | |
| Huo J, et al.(2020) Rewiring carbon flux in Escherichia coli using a bifunctional molecular switch.Metab Eng 61:47–57. | 2020 | 微生物およびモデル生物 | |
| Ihara K, et al.(2020) A missense mutation in the RSRSP stretch of Rbm20 causes dilated cardiomyopathy and atrial fibrillation in mice.Sci Rep 10(1):17894. | 2020 | その他 | |
| Jung Y and Yoon M. (2020) Oxytocin Receptor Expression in Stallion Testes and Epididymides.Domest Anim Endocrinol Sept 12 doi: 10.1016/j.domaniend.2020.106562 | 2020 | その他 | |
| JY Kim JY, et al.(2020) Inhibition of p300 by Garcinol Protects against Cisplatin-Induced Acute Kidney Injury through Suppression of Oxidative Stress, Inflammation, and Tubular Cell Death in Mice.Antioxidants (Basel) 9(12):E1271. | 2020 | その他 | |
| Kalchiem-Dekel O, et al.(2020) Apolipoprotein E Signals via TLR4 to Induce CXCL5 Secretion by Asthmatic Airway Epithelial Cells.Am J Respir Cell Mol Biol Apr 27 doi: 10.1165/rcmb.2019-0209OC. | 2020 | 細胞シグナル伝達 | |
| Kang DR, Shim KS.(2020) Early heat exposure effect on the heat shock proteins in broilers under acute heat stress.Poult Sci Dec 26 doi:10.1016/j.psj.2020.12.061. | 2020 | その他 | |
| Kim D, et al.(2020) Muscle-derived TRAIL negatively regulates myogenic differentiation.Exp Cell Res Jul 6 doi: 10.1016/j.yexcr.2020.112165. | 2020 | 細胞シグナル伝達 | |
| Kim DH, et al.(2020) TGF-β1-mediated Repression of SLC7A11 Drives Vulnerability to GPX4 Inhibition in Hepatocellular Carcinoma Cells.Cell Death Dis 11(5):406. | 2020 | がん | 肝臓 |
| Kim HY, et al.(2020) Epidermal growth factor (EGF)-based activatable probe for predicting therapeutic outcome of an EGF-based doxorubicin prodrug.J Control Release Aug 28 doi: 10.1016/j.jconrel.2020.08.046. | 2020 | 薬剤機構 | |
| Kim HY, et al.(2020) Protective Effect of Vitis labrusca Leaves Extract on Cardiovascular Dysfunction through HMGB1-TLR4-NFκB Signaling in Spontaneously Hypertensive Rats. | 2020 | その他 | |
| Kim J, et al.(2020) Gene expression amplification by nuclear speckle association.J Cell Bio 219:e201904046. | 2020 | その他 | |
| Kim J, et al.(2020) Lung-targeted Delivery of TGF-β Antisense Oligonucleotides to Treat Pulmonary Fibrosis.J Control Release 322:108−121. | 2020 | メソッド開発 | |
| Kim JJ, et al.(2020) Overexpression of a proton pumping gene OVP1 enhances salt stress tolerance, root growth and biomass yield by regulating ion balance in rice (Oryza sativa L.).Environ Exp Bot 175:104033. | 2020 | 植物科学 | |
| Kim JM, et al.(2020) Anti-Amnesic Effect of Walnut via the Regulation of BBB Function and Neuro-Inflammation in Aβ1-42-Induced Mice.Antioxidants (Basel) 9(10):E976. | 2020 | 神経生物学 | |
| Kim JM, et al.(2020) Matcha Improves Metabolic Imbalance-Induced Cognitive Dysfunction.Oxid Med Cell Longev 2020: 8882763. | 2020 | その他 | |
| Kim JY, et al.(2020) Kahweol Ameliorates Cisplatin-Induced Acute Kidney Injury through Pleiotropic Effects in Mice.Biomedicines 8(12):E572. | 2020 | がん研究 | 一般 |
| Knorr DY, et al.(2020) Acetylcholinesterase promotes apoptosis in insect neurons.Apoptosis Aug 5 doi: 10.1007/s10495-020-01630-4. | 2020 | 神経生物学 | |
| Kocsmár É, et al.(2020) Cross-testing of major molecular markers indicates distinct pathways of tumorigenesis in gastric adenocarcinomas and synchronous gastrointestinal stromal tumors.Sci Rep 10(1):22212. | 2020 | がん研究 | 胃がん |
| Kong Q, et al.(2020) Identification of AflR Binding Sites in the Genome of Aspergillus Flavus by ChIP-Seq.J Fungi (Basel) 6(2):E52. | 2020 | その他 | |
| Kumar A, et al.(2020) Toll‐like receptor 2 (TLR2) engages endoplasmic reticulum stress sensor IRE1α to regulate retinal innate responses in Staphylococcus aureus endophthalmitis.FASEB J Aug 19 doi: 10.1096/fj.202001393R. | 2020 | 細胞シグナル伝達 | |
| Kumari A, et al.(2020) Structural insights into actin filament recognition by commonly used cellular actin markers.EMBO J 39(14):e104006. | 2020 | その他 | |
| Lapitz A, et al.(2020) Patients With Cholangiocarcinoma Present Specific RNA Profiles in Serum and Urine Extracellular Vesicles Mirroring the Tumor Expression: Novel Liquid Biopsy Biomarkers for Disease Diagnosis.Cells 9(3):721. | 2020 | 疾病研究：バイオマーカー研究 | |
| Lata E, et al.(2020) Thin-layer chromatographic quantification of magnolol and honokiol in dietary supplements and selected biological properties of these preparations.J Chromatogr A 1625: 461230. | 2020 | その他 | |
| Lee EH, et al.(2020) Knockdown of TRPM7 prevents tumor growth, migration, and invasion through the Src, Akt, and JNK pathway in bladder cancer.BMC Urol 20(1):145. | 2020 | 細胞シグナル伝達 | |
| Lee J, et al.(2020) Androsamide, a Cyclic Tetrapeptide from a Marine Nocardiopsis sp., Suppresses Motility of Colorectal Cancer Cells.J Nat Prod Sep 28 doi: 10.1021/acs.jnatprod.0c00815. | 2020 | がん研究 | 大腸がん |
| Lee MH, et al.(2020) Licorice extract suppresses adipogenesis through regulation of mitotic clonal expansion and adenosine monophosphate‐activated protein kinase in 3T3‐L1 cells. | 2020 | その他 | |
| Lee R, et al.(2020) Effects of Gintonin-Enriched Fraction on Hippocampal Gene Expressions.Integr Med Res July 15 doi: 10.1016/j.imr.2020.100475. | 2020 | メソッド開発 | |
| Lee SM, et al.(2020) FABP3-mediated membrane lipid saturation alters fluidity and induces ER stress in skeletal muscle with aging.Nat Commun 11(1):5661. | 2020 | その他 | |
| Li D, et al.(2020) Synergism of cisplatin-oleanolic acid co-loaded hybrid nanoparticles on gastric carcinoma cells for enhanced apoptosis and reversed multidrug resistance.Drug Deliv 27(1):191−199. | 2020 | がん | 胃 |
| Li G, et al.(2020) Identification and Characterization of the Lactating Mouse Mammary Gland Citrullinome.Int J Mol Sci 21(7):2634. | 2020 | その他 | |
| Li J, et al.(2020) CircRNA TADA2A relieves idiopathic pulmonary fibrosis by inhibiting proliferation and activation of fibroblasts. | 2020 | その他 | |
| Li P, et al.(2020) LINC00271 inhibits epithelial-mesenchymal transition of papillary thyroid cancer cells by downregulating trefoil factor 3 expression.Aging Pathobiology and Therapeutics 2(2):78–85. | 2020 | がん研究 | 一般 |
| Li Y, et al.(2020) microRNA-103a-3p confers protection against lipopolysaccharide-induced sepsis and consequent multiple organ dysfunction syndrome by targeting HMGB1.Infect Genet Evol Dec 14 doi: 10.1016/j.meegid.2020.104681 doi: 10.1016/j.meegid.2020.104681. | 2020 | その他 | |
| Liang L, et al.(2020) miR-4429 Regulates the Proliferation, Migration, Invasion, and Epithelial-Mesenchymal Transition of Cervical Cancer by Targeting FOXM1.Cancer Manag Res 12:5301–5312. | 2020 | がん研究 | 子宮頸がん |
| Lim D, et al.(2020) Targeted Delivery of the Mitochondrial Target Domain of Noxa to Tumor Tissue via Synthetic Secretion System in E. coli.Front Bioeng Biotechnol | 2020 | 薬剤機構 | |
| Lin YM, et al.(2020) Nerolidol improves cardiac function in spontaneously hypertensive rats by inhibiting Cardiac Inflammation and remodelling associated TLR4/NF-κB signaling cascade.Food Chem Toxicol Nov 17 doi: 10.1016/j.fct.2020.111837. | 2020 | 細胞シグナル伝達 | |
| Linke V, et al.(2020) A large-scale genome–lipid association map guides lipid identification.Nat Metab Sep 21 doi: 10.1038/s42255-020-00278-3. | 2020 | その他 | |
| Liu EA, et al.(2020) Fbxo2 mediates clearance of damaged lysosomes and modifies neurodegeneration in the Niemann-Pick C brain.JCI Insight Sep 15 doi: 10.1172/jci.insight.136676. | 2020 | 神経生物学 | |
| Liu R, et al.(2020) GPR120 Agonist GW9508 Ameliorated Cellular Senescence Induced by ox-LDL.ACS Omega 5:32195−32202. | 2020 | 細胞シグナル伝達 | |
| Liu Y, et al.(2020) Ginsenoside Rh2 inhibits HeLa cell energy metabolism and induces apoptosis by upregulating voltage‑dependent anion channel 1.Int J Mol Med 46(5):1695–1706. | 2020 | その他 | |
| Lu CH, et al.(2020) Fic Proteins Inhibit the Activity of Topoisomerase IV by AMPylation in Diverse Bacteria.Front Microbiol August 26 doi: 10.3389/fmicb.2020.02084. | 2020 | 微生物およびモデル生物 | |
| Lu T, et al.(2020 Up-regulation of hypoxia-inducible factor antisense as a novel approach to treat ovarian cancer.Theranostics 10(15):6959–6976. | 2020 | がん研究 | 卵巣 |
| Luo L, et al.(2020) Sestrin 2 Attenuates Sepsis-Associated Encephalopathy Through the Promotion of Autophagy in Hippocampal Neurons.J Cell Mol Med doi:10.1111/jcmm.15313. | 2020 | 神経生物学 | |
| Ma B, et al.(2020) Differential Histone Distribution Patterns in Induced Asymmetrically Dividing Mouse Embryonic Stem Cells.Cell Rep 32(6):108003. | 2020 | 幹細胞 | |
| Mariano Jr EB, et al.(2020) Relationship of Fibronectic 1 (FN1) to the Extended Semen Shelf Life of Duson and Phillipine Native Boar-quezon at Different Storage Temperatures.Philipp J Vet Anim Sci 46(1):12–19. | 2020 | その他 | |
| Marín-Ramos NI, et al.(2020) MiR-18a inhibits BMP4 and HIF-1α Normalizing Brain Arteriovenous Malformations.Circ Res Aug 5 doi: 10.1161/CIRCRESAHA.119.316317. | 2020 | 神経生物学 | |
| Martin-Perez M, et al.(2020) PKC downregulation upon rapamycin treatment attenuates mitochondrial disease.Nat Metab 2(12):1472-1481 | 2020 | Mitochondrial studies | |
| McClellan EB, et al.(2020) L‐citrulline treatment alters the structure of the pulmonary circulation in hypoxic newborn pigs.Pediatr Pulmonol Jul 14 doi: 10.1002/ppul.24960. | 2020 | 細胞シグナル伝達 | |
| Merlo, S, et al.(2020) SIRT1 Mediates Melatonin's Effects on Microglial Activation in Hypoxia: In Vitro and In Vivo Evidence.Biomolecules 10(3):364. | 2020 | 細胞シグナル伝達 | |
| Miteva K, et al.(2020) Cardiotrophin-1 Deficiency Abrogates Atherosclerosis Progression.Sci Rep 10(1):5791. | 2020 | その他 | |
| Morel G, et al.(2020) Mandibular‐Pelvic‐Patellar syndrome (MPP) is a novel PITX1‐related disorder due to alteration of PITX1 transactivation ability.Hum Mutat Jun 29 doi: 10.1002/humu.24070. | 2020 | その他 | |
| Móricz AM, et al.(2020) Bioactive clerodane diterpenes of giant goldenrod (Solidago gigantea Ait.) root extract.J Chromatogr A Nov 19 doi: 10.1016/j.chroma.2020.461727. | 2020 | 植物科学 | |
| Móricz ÁM, et al.(2020) High-performance thin-layer chromatography hyphenated to high-performance liquid chromatography-diode array detection-mass spectrometry for characterization of coeluting isomers.Talanta 219: 121306. | 2020 | メソッド開発 | |
| Morotti A, et al.(2020) The oncosuppressors MEN1 and CDC73 are involved in lncRNAs deregulation in human parathyroid tumors.J Bone Miner Res Aug 11 doi: 10.1002/jbmr.4154. | 2020 | がん研究 | 一般 |
| Mu J, et al.(2020) Effect of Lactobacillus plantarum KFY02 isolated from naturally fermented yogurt on the weight loss in mice with high-fat diet-induced obesity via PPAR-α/γ signaling pathway.J Funct Foods 75 104264. | 2020 | 細胞シグナル伝達 | |
| Mu J, et al.(2020) Lactobacillus fermentum CQPC06 in Naturally Fermented Pickles Prevents Non-alcoholic Fatty Liver Disease by Stabilizing the Gut-liver Axis in Mice.Food Funct Sep 18 doi: 10.1039/d0fo01823f. | 2020 | 微生物およびモデル生物 | |
| Nakamura-Bencomo s, et al.(2020) Recombinant human lactoferrin carrying humanized glycosylation exhibits antileukemia selective cytotoxicity, microfilament disruption, cell cycle arrest, and apoptosis activities.Invest New Drugs Oct 16 doi: 10.1007/s10637-020-01020-2. | 2020 | がん研究 | 一般 |
| Neff AM, et al.(2020) Insulin Signaling Via Progesterone-Regulated Insulin Receptor Substrate 2 is Critical for Human Uterine Decidualization.Endocrinology 161:bqz021. | 2020 | 細胞シグナル伝達 | |
| Nolte WW, et al.(2020) Screening trimethoprim primary metabolites for covalent binding to albumin.Med Chem Res 29:1238–1246. | 2020 | その他 | |
| Ogawa M, et al.(2020) Contribution of Extracellular O-GlcNAc to the Stability of Folded Epidermal Growth Factor-Like Domains and Notch1 Trafficking.Biochem Biophys Res Commun Mar 19 doi: 10.1016/j.bbrc.2020.03.066. | 2020 | 細胞シグナル伝達 | |
| Othmène YB, et al.(2020) Oxidative stress, DNA damage and apoptosis induced by tebuconazole in kidney of male Wistar rats.Chem Biol Interact Jul 28 doi: 10.1016/j.cbi.2020.109114. | 2020 | 細胞シグナル伝達 | |
| Othmène YB, et al.(2020) Tebuconazole induces ROS-dependent cardiac cell toxicity by activating DNA damage and mitochondrial apoptotic pathway.Ecotoxicol Environ Saf 204:111040. | 2020 | 細胞シグナル伝達 | |
| Owiredu S, et al.(2020) In vitro Comparison of Hydroxocobalamin (B12a) and the Mitochondrial Directed therapy by a Succinate Prodrug in a Cellular Model of Cyanide Poisoning.Toxicol Rep 7:1263–1271. | 2020 | Mitochondrial studies | |
| Özliseli E, et al.(2020) Rational evaluation of human serum albumin coated mesoporous silica nanoparticles for xenogenic-free stem cell therapies.Colloids Surf A Physico Chem Eng Asp 600:124945. | 2020 | メソッド開発 | |
| Paldino E, et al.(2020) Modulation of Inflammasome and Pyroptosis by Olaparib, a PARP-1 Inhibitor, in the R6/2 Mouse Model of Huntington's Disease.Cells 9(10):E2286. | 2020 | 神経生物学 | |
| Paldino E, et al.(2020) Pyroptotic cell death in the R6/2 mouse model of Huntington's disease: new insight on the inflammasome.Cell Death Discov 6:69. | 2020 | 神経生物学 | |
| Pan H, et al.(2020) Lactobacillus plantarum KFY02 enhances the prevention of CCl4-induced liver injury by transforming geniposide into genipin to increase the antioxidant capacity of mice.J Funct Foods 73:104128. | 2020 | 微生物およびモデル生物 | |
| Pan H, et al.(2020) Mesenchymal Stem Cells Combined With Tissue Fusion Technology Promoted Wound Healing in Porcine Bowel Anastomosis.Stem Cells Int 2020:5142797. | 2020 | 幹細胞 | |
| Pan H, et al.(2020) Mesenchymal Stem Cells Combined with Tissue Fusion Technology Promoted Wound Healing in Porcine Bowel Anastomosis.Stem Cells Int Feb 12 doi: 10.1155/2020/5142797. | 2020 | その他 | |
| Paradzik M, et al.(2020) KANK2 Links αVβ5 Focal Adhesions to Microtubules and Regulates Sensitivity to Microtubule Poisons and Cell Migration.Front Cell Dev Biol 8:125. | 2020 | その他 | |
| Park M, et al.(2020) Anti-FLT3 Nanoparticles for Acute Myeloid Leukemia: Preclinical Pharmacology and Pharmacokinetics.J Control Release 324:317-329. | 2020 | がん | 一般 |
| Pellavio G, et al.(2020) HPV Infection Affects Human Sperm Functionality by Inhibition of Aquaporin-8.Cells 9(5):E1241. | 2020 | その他 | |
| Pelletier J, et al.(2020) Nucleotide depletion reveals the impaired ribosome biogenesis checkpoint as a barrier against DNA damage.EMBO J 39(13):e103838. | 2020 | その他 | |
| Peng KC, et al.(2020) Expression of L-amino acid oxidase of Trichoderma harzianum in tobacco confers resistance to Sclerotinia sclerotiorum and Botrytis cinereal.Plant Sci Nov 24 doi: 10.1016/j.plantsci.2020.110772. | 2020 | 植物科学 | |
| Pires Da Silva J, et al.(2020) SIRT1 Protects the Heart from ER Stress-Induced Injury by Promoting eEF2K/eEF2-Dependent Autophagy.Cells 9(2):426. | 2020 | 細胞シグナル伝達 | |
| Plotnikov A, et al.(2020) PRMT1 inhibition induces differentiation of colon cancer cells.Sci Rep 10(1):20030. | 2020 | がん研究 | 結腸がん |
| Prieto-Garcia C, et al.(2020) Maintaining protein stability of ∆Np63 via USP28 is required by squamous cancer cells.MBO Mol Med 12(4):e11101. | 2020 | がん研究 | 扁平上皮がん |
| Protective effects of polymethoxyflavone-rich cold-pressed orange peel oil against ultraviolet B-induced photoaging on mouse skin.J Funct Foods 67:103834. | 2020 | その他 | |
| Qian B, et al.(2020) Ameliorative Effect of Sinapic Acid on Dextran Sodium Sulfate-(DSS-) Induced Ulcerative Colitis in Kunming (KM) Mice.Oxid Med Cell Longev 2020: 8393504. | 2020 | その他 | |
| Qu W, Li L. (2020) Loss of TREM2 confers resilience to synaptic and cognitive impairment in aged mice.J Neurosci Nov 2 doi: 10.1523/JNEUROSCI.2193-20.2020. | 2020 | 神経生物学 | |
| Raducanu V, et al.(2020) Simplified detection of polyhistidine-tagged proteins in gels and membranes using a UV-excitable dye and a multiple chelator head pair.J Biol Chem Jul 9 doi: 10.1074/jbc.RA120.014132. | 2020 | メソッド開発 | |
| Raducanu VS, et al.(2020) Two Chromatographic Schemes for Protein Purification Involving the Biotin/Avidin Interaction Under Native Conditions.J Chromatography A Mar 17 doi: 10.1016/j.chroma.2020.461051. | 2020 | メソッド開発 | |
| Reichermeier KM, et al.(2020) PIKES Analysis Reveals Response to Degraders and Key Regulatory Mechanisms of the CRL4 Network.Mol Cell 77:1–15. | 2020 | 細胞シグナル伝達 | |
| Roman B, et al.(2020) Nuclear-mitochondrial Communication Involving miR-181c Plays an Important Role in Cardiac Dysfunction During Obesity.J Mol Cell Cardiol 144:87−96. | 2020 | Mitochondrial studies | |
| Sadiki A, et al.(2020) Site-specific Bioconjugation and Convergent Click Chemistry Enhances Antibody-Chromophore Conjugate Binding Efficiency.Photochem Photobiol Feb 21 doi: 10.1111/php.13231. | 2020 | メソッド開発 | |
| Salgado-Lora MG, et al.(2020) Prolactin and Estradiol are Epigenetic Modulators in Bovine Mammary Epithelial Cells during Staphylococcus aureus Infection.Pathogens 9(7):E520. | 2020 | その他 | |
| Samanas NB, et al.(2020) Defective Nucleotide-Dependent Assembly and Membrane Fusion in Mfn2 CMT2A Variants Improved by Bax.Life Sci Alliance 3(5):e201900527. | 2020 | Mitochondrial studies | |
| Sciamanna G, et al.(2020) Optogenetic Activation of Striatopallidal Neurons Reveals Altered HCN Gating in DYT1 Dystonia.Cell Rep 31(7):107644. | 2020 | 神経生物学 | |
| Seltzer J, et al.(2020) Interleukin-1 Receptor Associated Kinase (IRAK) Signaling in Kaposi Sarcoma-associated Herpesvirus (KSHV) Induced Primary Effusion Lymphoma.J Virol.JVI.02123-19. | 2020 | がん | カポジ肉腫 |
| SH Siddiqui SH, et al.(2020) Direct exposure to mild heat stress stimulates cell viability and heat shock protein expression in primary cultured broiler fibroblasts.Cell Stress Chaperones Jul 22 doi: 10.1007/s12192-020-01140-x. | 2020 | 一般 | |
| Shahrouzi P, et al.(2020) Genomic and Functional Regulation of TRIB1 Contributes to Prostate Cancer Pathogenesis.Cancers (Basel) 12(9):E2593. | 2020 | がん研究：一般 | |
| Shanmugapriya K, et al.(2020) Cellulose nanocrystals/nanofibrils loaded astaxanthin nanoemulsion for the induction of apoptosis via ROS-dependent mitochondrial dysfunction in cancer cells under photobiomodulation.Int J Biol Macromol 149:165−177. | 2020 | がん | 皮膚 |
| Shanmugapriya K, et al.(2020) Epidermal Growth Factor Receptor Conjugated Fucoidan/Alginates Loaded Hydrogel for Activating EGFR/AKT Signaling Pathways in Colon Cancer Cells During Targeted Photodynamic Therapy.Int J Biol Macromol May 6 doi: 10.1016/j.ijbiomac.2020.05.008. | 2020 | がん | 大腸 |
| Shanmugapriya K, et al.(2020) Fucoidan-loaded hydrogels facilitates wound healing using photodynamic therapy by in vitro and in vivo evaluation.Carbohydr Polym 247:116624. | 2020 | 薬剤機構 | |
| Shi H, et al.(2020) Retinal capillary degeneration and blood-retinal barrier disruption in murine models of Alzheimer's disease.Acta Neuropathol Commun 8(1):202. | 2020 | 神経生物学 | |
| Shin CH, et al.(2020) Exosomal miRNA-19a and miRNA-614 Induced by Air Pollutants Promote Proinflammatory M1 Macrophage Polarization via Regulation of RORα Expression in Human Respiratory Mucosal Microenvironment.J Immunol Oct 28 doi: 10.4049/jimmunol.2000456. | 2020 | その他 | |
| Siddiqui SH, et al.(2020) Chronic heat stress regulates the relation between heat shock protein and immunity in broiler small intestine.Sci Rep 10(1):18872. | 2020 | その他 | |
| Siregar, AS, et al.(2020) Dipeptide YA is Responsible for the Positive Effect of Oyster Hydrolysates on Alcohol Metabolism in Single Ethanol Binge Rodent Models.Mar Drugs 18(10):E512. | 2020 | その他 | |
| Somayajulu M, et al.(2020) Airborne Particulates Affect Corneal Homeostasis and Immunity.Invest Ophthalmol Vis Sci 61(4):23. | 2020 | その他 | |
| Soncini D, et al.(2020) Amino acid depletion triggered by ʟ-asparaginase sensitizes MM cells to carfilzomib by inducing mitochondria ROS-mediated cell death.Blood Adv 4(18):4312–4326 | 2020 | Mitochondrial studies | |
| Srivastava T, et al.(2020) Upregulated proteoglycan-related signaling pathways in fluid flow shear stress-treated podocytes.Am J Physiol Renal Physiol Jul 6 doi: 10.1152/ajprenal.00183.2020. | 2020 | その他 | |
| Stieg DC, et al.(2020) The extent of cyclin C promoter occupancy directs changes in stress-dependent transcription.J Biol Chem Sep 15 doi: 10.1074/jbc.RA120.015215. | 2020 | その他 | |
| Sun G, et al.(2020) Phoenixin-20 suppresses lipopolysaccharide-induced inflammation in dental pulp cells.Chem Biol Interact 318:108971. | 2020 | 細胞シグナル伝達 | |
| Sun Y, et al.(2020) Therapeutic effect and mechanisms of the novel monosulfactam 0073.Antimicrob Agents Chemother Jul 27 doi: 10.1128/AAC.00529-20. | 2020 | 微生物およびモデル生物 | |
| Tayebi M, et al.(2020) Exosome Purification and Analysis Using a Facile Microfluidic Hydrodynamic Trapping Device.Anal Chem Jul 17 doi: 10.1021/acs.analchem.0c02006. | 2020 | メソッド開発 | |
| Teng Y, et al.(2020) Lactobacillus plantarumLP104 ameliorates hyperlipidemia induced by AMPK pathways in C57BL/6N mice fed high-fat diet.J Functional Foods 64:103665. | 2020 | 微生物およびモデル生物 | |
| Thibeault PE, et al.(2020) Role of the Helix-8 and C-Terminal Tail in Regulating Proteinase Activated Receptor 2 Signaling.ACS Pharmacol Transl Sci Aug 10 doi:10.1021/acsptsci.0c00039. | 2020 | 細胞シグナル伝達 | |
| Thongnak L, et al.(2020) Mitigation of renal inflammation and endoplasmic reticulum stress by vildagliptin and statins in high-fat high-fructose diet-induced insulin resistance and renal injury in rats.Biochim Biophys Acta Mol Cell Biol Lipids 1865(9):158755. | 2020 | その他 | |
| Tu MM, et la. (2020) Inhibition of the CCL2 receptor, CCR2, enhances tumor response to immune checkpoint therapy.Commun Biol 3(1):720. | 2020 | がん研究 | 一般 |
| Vargas AM, et al.(2020) Methamphetamine Alters the TLR4 Signaling Pathway, NF-κB Activation, and Pro-Inflammatory Cytokine Production in LPS-challenged NR-9460 Microglia-Like Cells.Mol Immunol 121:159−166. | 2020 | 細胞シグナル伝達 | |
| Verma DK, et al.(2020) The SUMO conjugase Ubc9 protects Dopaminergic cells from cytotoxicity and enhances the stability of α-synuclein in Parkinson's disease models. | 2020 | 神経生物学 | |
| Wang H, et al.(2020) DPP-4 Inhibitor Linagliptin Ameliorates Oxidized LDL-Induced THP-1 Macrophage Foam Cell Formation and Inflammation.Drug Des Devel Ther 2020(14):3929–3940. | 2020 | その他 | |
| Wang H, et al.(2020) Long non-coding RNA LICPAR regulates atrial fibrosis via TGF-β/Smad pathway in atrial fibrillation.Tissue Cell 67:101440. | 2020 | 細胞シグナル伝達 | |
| Wang Y, et al.(2020) Pediococcus pentosaceus PP04 Ameliorates High-Fat Diet-Induced Hyperlipidemia by Regulating Lipid Metabolism in C57BL/6N Mice.J Agric Food Chem Dec 10 doi: 10.1021/acs.jafc.0c05060. | 2020 | その他 | |
| Wang Y, et al.(2020) Rapamycin improves renal injury induced by Iodixanol in diabetic rats by deactivating the mTOR/p70S6K signaling pathway.Life Sci 259:118284 | 2020 | 細胞シグナル伝達 | |
| Wang Y, et al.(2020) TFAP2C facilitates somatic cell reprogramming by inhibiting c-Myc-dependent apoptosis and promoting mesenchymal-to-epithelial transition.Cell Death Dis 11(6):482. | 2020 | 幹細胞 | |
| Wang Z, et al.(2020) Kaempferol Ameliorates Cisplatin Induced Nephrotoxicity by Modulating Oxidative Stress, Inflammation and Apoptosis via ERK and NF-κB Pathways.AMB Express 10(1):58. | 2020 | 細胞シグナル伝達 | |
| Widyastuti HP, et al.(2020) Gene expression profiling of fibroblasts in a family with LMNA-related cardiomyopathy reveals molecular pathways implicated in disease pathogenesis.BMC Med Genet 21(1):152. | 2020 | 疾病研究：バイオマーカー研究 | |
| Widyastuti HP, et al.(2020) Gene expression profiling of fibroblasts in a family with LMNA-related cardiomyopathy reveals molecular pathways implicated in disease pathogenesis.BMC Med Genet 21(1):152. | 2020 | 疾病研究：バイオマーカー研究 | |
| Wössner N, et al.(2020) Sirtuin 1 Inhibiting Thiocyanates (S1th)-A New Class of Isotype Selective Inhibitors of NAD + Dependent Lysine Deacetylases.Front Oncol 10:657. | 2020 | がん | 一般 |
| Wu A, et al.(2020) DNMT1 Promotes Cell Proliferation via Methylating hMLH1 and hMSH2 Promoters in EGFR-mutated Non-Small Cell Lung Cancer.J Biochem Mar 25 doi: 10.1093/jb/mvaa034. | 2020 | がん | 肺 |
| Wu C, et al.(2020) Evaluation of the Post-Treatment Anti-Inflammatory Capacity of Osteoarthritic Chondrocytes: An in vitro Study Using Baicalein.Regen Ther14:177−183. | 2020 | 細胞シグナル伝達 | |
| Xiao P, et al.(2020) LncRNA NEAT1 regulates chondrocyte proliferation and apoptosis via targeting miR-543/PLA2G4A axis. | 2020 | その他 | |
| Xin L, et al.(2020) Methionine represses the autophagy of gastric cancer stem cells via promoting the methylation and phosphorylation of RAB37.Cell Cycle Sep 14 doi: 10.1080/15384101.2020.1814044. | 2020 | がん研究：胃がん | |
| Xin S, Ye L. (2020) Knockdown of long non‑coding RNA CCAT2 suppresses the progression of thyroid cancer by inhibiting the Wnt/β‑catenin pathway.Int J Mol Med Sept 4 doi: 10.3892/ijmm.2020.4761. | 2020 | がん研究 | 一般 |
| Xin X, et al.(2020) Redox-responsive nanoplatform for codelivery of miR-519c and gemcitabine for pancreatic cancer therapy.Sci Adv 6(46):eabd6764. | 2020 | がん研究 | 膵臓がん |
| Xu WF, et al.(2020) Gasdermin E-derived caspase-3 Inhibitors Effectively Protect Mice From Acute Hepatic Failure.Acta Pharmacol Sin May 26 doi: 10.1038/s41401-020-0434-2. | 2020 | 薬剤機構 | |
| Xue W, et al.(2020) Rotenone Restrains the Proliferation, Motility and Epithelial-Mesenchymal Transition of Colon Cancer Cells and the Tumourigenesis in Nude Mice via PI3K/AKT Pathway.Clin Exp Pharmacol Physiol Apr 13 doi: 10.1111/1440-1681.13320. | 2020 | がん | 大腸 |
| Yang M, et al.(2020) Preventive effect of lemon seed flavonoids on carbon tetrachloride-induced liver injury in mice.RSC Adv 10:12800−128009. | 2020 | その他 | |
| Yang X, et al.(2020) Inhibition of ITGB1 enhance the anti-tumor effect of cetuximab in colorectal cancer cell.Medicine (Baltimore) 99(27):e20944. | 2020 | がん研究 | 大腸がん |
| Yang Y, et al.(2020) Discovery of Novel Inhibitors Targeting Multi-UDP-hexose Pyrophosphorylases as Anticancer Agents.Molecules 25(3):645. | 2020 | がん | 一般 |
| Yao Q, et al.(2020) Unsaturated fatty acid-enriched extract from Hippophae rhamnoides seed reduces skin dryness through up-regulating aquaporins 3 and hyaluronan synthetases 2 expressions.J Cosmet Dermatol Jul 8 doi: 10.1111/jocd.13482 | 2020 | その他 | |
| Yee YH, et al.(2020) Sustained IKKβ Phosphorylation and NF-κB Activation by Superoxide-induced Peroxynitrite-mediated Nitrotyrosine Modification of B56γ3 and PP2A Inactivation.Redox Biol Dec 8 doi: 10.1016/j.redox.2020.101834. | 2020 | 細胞シグナル伝達 | |
| Yi R, et al.(2020) Intervention effects of lotus leaf flavonoids on gastric mucosal lesions in mice infected with Helicobacter pylori.RSC Adv 10:23510. | 2020 | 植物科学 | |
| Yoon JJ, et al.(2020) Betulinic Acid Protects DOX-Triggered Cardiomyocyte Hypertrophy Response through the GATA-4/Calcineurin/NFAT Pathway.Molecules 26(1):E53. | 2020 | 細胞シグナル伝達 | |
| Zamorano-Leon JJ, et al.(2020) Factor Xa Inhibition by Rivaroxaban Modified Mitochondrial-Associated Proteins in Human Abdominal Aortic Aneurysms.Ann Vasc Surg Mar 12 doi: 10.1016/j.avsg.2020.02.005. | 2020 | その他 | |
| Zanin S, et al.(2020) Intracellular protein kinase CK2 inhibition by ferulic acid-based trimodal nanodevice.Int J Biol Macromol 165(Pt A):701–712. | 2020 | その他 | |
| Zeng N, et al.(2020) LEFTY2/endometrial Bleeding-Associated Factor Up-Regulates Na+ Coupled Glucose Transporter SGLT1 Expression and Glycogen Accumulation in Endometrial Cancer Cells.PLoS One 15(4):e0230044. | 2020 | がん | 子宮内膜 |
| Zeng Y, et al.(2020) The GPR55 Antagonist CID16020046 Mitigates Advanced Glycation End Products (AGEs)- Induced Chondrocyte Activation.Chem Biol Interact 325:109088. | 2020 | 細胞シグナル伝達 | |
| Zeng ZL, et al.(2020) Highly Expressed lncRNA FOXD3-AS1 Promotes Non-Small Cell Lung Cancer Progression via Regulating miR-127-3p/mediator Complex Subunit 28 Axis.Euro Rev Med Pharmacol Sci 24: 2525−2538. | 2020 | がん | 肺 |
| Zhang H, et al.(2020) Silencing TTTY15 mitigates hypoxia-induced mitochondrial energy metabolism dysfunction and cardiomyocytes apoptosis via TTTY15/let-7i-5p and TLR3/NF-κB pathways. | 2020 | 細胞シグナル伝達 | |
| Zhang H, et al.(2020) Structural, physicochemical and functional properties of Semen Ziziphi Spinosae protein.RSC Adv 10:29555. | 2020 | 植物科学 | |
| Zhang J, et al.(2020) Identifying Mutation Hotspots Reveals Pathogenetic Mechanisms of KCNQ2 Epileptic Encephalopathy.Sci Rep 10(1):4756. | 2020 | 神経生物学 | |
| Zhang W, et al.(2020) LncRNA DANCR regulates osteosarcoma migration and invasion by targeting miR-149/MSI2 axis.Eur Rev Med Pharmacol Sci 24(12):6551–6560. | 2020 | がん研究 | 一般 |
| Zhao L, et al.(2020) Puerarin alleviates coronary heart disease via suppressing inflammation in a rat model.Gene 771:145354. | 2020 | 細胞シグナル伝達 | |
| Zhao Q, et al.(2020) Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output.Cell Sep 5 doi: 10.1016/j.cell.2020.08.009. | 2020 | Mitochondrial studies | |
| Zhao T, et al.(2020) PD‑L1 expression increased by IFN‑γ via JAK2‑STAT1 signaling and predicts a poor survival in colorectal cancer.Oncol Lett May 20 doi.org/10.3892/ol.2020.11647. | 2020 | がん | 大腸 |
| Zimmer A, et al.(2020) The progression of pulmonary arterial hypertension induced by monocrotaline is characterized by lung nitrosative and oxidative stress, and impaired pulmonary artery reactivity.Eur J Pharmacol Nov 5 doi: 10.1016/j.ejphar.2020.173699. | 2020 | その他 | |
| Arreal L, et al.(2019) Targeting PML in triple negative breast cancer elicits growth suppression and senescence.Cell Death Differ Oct 1 doi: 10.1038/s41418-019-0407-5. | 2019 | がん | 乳房 |
| Bellot GL, et al.(2019) MnSOD is implicated in accelerated wound healing upon Negative Pressure Wound Therapy (NPWT): A case in point for MnSOD mimetics as adjuvants for wound management.Redox Biol 20:307−320. | 2019 | 薬剤機構 | |
| Bhatt T, et al.(2019) Sustained Secretion of the Antimicrobial Peptide S100A7 Is Dependent on the Downregulation of Caspase-8.Cell Rep 29(9):2546−2555.e4. | 2019 | 細胞シグナル伝達 | |
| Bloomfield M, Louie MC (2019) Chronic cadmium exposure decreases the dependency of MCF7 breast cancer cells on ERα.Sci Rep 9(1):12135. | 2019 | がん | 乳房 |
| Chi X, et al.(2019) A system for site-specific integration of transgenes in mammalian cells.PLoS One 14(7):e0219842. | 2019 | メソッド開発 | |
| Courtney AH, et al.(2019) CD45 functions as a signaling gatekeeper in T cells.Sci Signal Oct 22 doi: 10.1126/scisignal.aaw8151. | 2019 | 細胞シグナル伝達 | |
| Depledge DP, et al.(2019) Direct RNA sequencing on nanopore arrays redefines the transcriptional complexity of a viral pathogen.Nat Commun 10(1):754. | 2019 | その他 | |
| Dong Q, et al.(2019) A signal-flexible gene diagnostic strategy coupling loop-mediated isothermal amplification with hybridization chain reaction.Anal Chim Acta 1079:171−179. | 2019 | メソッド開発 | |
| Durante L, et al.(2019) Characterization of the GPR1/FUN34/YaaH protein family in the green microalga Chlamydomonas suggests their role as intracellular membrane acetate channels.Plant Direct 3(6):e00148. | 2019 | 植物科学 | |
| Englehart EA, Hoppins S. (2019) A catalytic domain variant of Mitofusin requiring a wildtype paralog for function uncouples mitochondrial outer-membrane tethering and fusion.J Biol Chem April 1 doi: 10.1074/jbc.RA118.006347. | 2019 | Mitochondrial studies | |
| Funabara D, et al.(2019) Phosphorylation Properties of the N-Terminal Region of Twitchin from Molluscan Catch Muscle.American Journal of Molecular Biology 9:110−120. | 2019 | 細胞シグナル伝達 | |
| Gansukh E, et al.(2019) Chemopreventive Effect of β-Cryptoxanthin on Human Cervical Carcinoma (HeLa) Cells Is Modulated through Oxidative Stress-Induced Apoptosis.Antioxidants (Basel) 9(1):28. | 2019 | 薬剤機構 | |
| Gao M, et al.(2019) Identification of a Cry1Fa binding site of cadherin in Plutella xylostella through fragment exchanging and molecular docking methods.Int J Biol Macromol 146:62-69. | 2019 | メソッド開発 | |
| Groveman BR, et al.(2019) Sporadic Creutzfeldt-Jakob disease prion infection of human cerebral organoids.Acta Neuropathol Commun 7(1):90. | 2019 | 神経生物学 | |
| Hohl A, et al.(2019) Engineering a Polyspecific Pyrrolysyl-tRNA Synthetase by a High Throughput FACS Screen.Sci Rep 9(1):11971. | 2019 | メソッド開発 | |
| Honda JR, et al.(2019) Nontuberculous Mycobacteria Show Differential Infectivity and Use Phospholipids to Antagonize LL-37.Am J Respir Cell Mol Biol Sep 23 doi: 10.1165/rcmb.2018-0278OC. | 2019 | 微生物およびモデル生物 | |
| Huang M, et al.(2019) HMGB1 Mediates Paraquat-Induced Neuroinflammatory Responses via Activating RAGE Signaling Pathway.Neurotox Res Dec 20 doi: 10.1007/s12640-019-00148-1. | 2019 | 神経生物学 | |
| Huang TL, et al.(2019) The therapeutic effect of aucubin-supplemented hyaluronic acid on interleukin-1 beta-stimulated human articular chondrocytes.Phytomedicine 53:1−8. | 2019 | その他 | |
| Jia QL, et al.(2019) Fisetin, via CKIP-1/REGγ, limits oxidized LDL-induced lipid accumulation and senescence in RAW264.7 macrophage-derived foam cells.Eur J Pharmacol Oct 23 doi: 10.1016/j.ejphar.2019.172748. | 2019 | その他 | |
| Kang D, et al.(2019) Heat Treatment at an Early Age Has Effects on the Resistance to Chronic Heat Stress on Broilers.Animals (Basel) 9(12):1022. | 2019 | その他 | |
| Kang JY, et al.(2019) 4,5-dicaffeyolquinic acid improves high-fat diet-induced cognitive dysfunction through the regulation of insulin degrading enzyme.J Food Biochem 43(7):e12855. | 2019 | 神経生物学 | |
| Karaszi K, et al.(2019) Increased placental expression of placental protein 5 (PP5) / tissue factor pathway inhibitor-2 (TFPI-2) in women with preeclampsia and HELLP syndrome: Relevance to impaired trophoblast invasion? Placenta 76:30−39. | 2019 | 疾病研究：バイオマーカー研究 | |
| Kim DI, et al.(2019) Comparison of asthma phenotypes in OVA-induced mice challenged via inhaled and intranasal routes.BMC Pulm Med 19(1):241. | 2019 | その他 | |
| Lee BR, et al.(2019) Distinct role of Sirtuin 1 (SIRT1) and Sirtuin 2 (SIRT2) in inhibiting cargo-loading and release of extracellular vesicles.Sci Rep 9(1):20049. | 2019 | 細胞シグナル伝達 | |
| Lee JY, et al.(2019) Red Blood Cell Membrane Bioengineered Zr-89 Labelled Hollow Mesoporous Silica Nanosphere for Overcoming Phagocytosis.Sci Rep 9(1):7419. | 2019 | がん | 一般 |
| Liu B, et al.(2019) Effects of Lactobacillus plantarum CQPC01-fermented soybean milk on activated carbon-induced constipation through its antioxidant activity in mice.Food Sci Nutr 7(6):2068−2082. | 2019 | 微生物およびモデル生物 | |
| Liu L, et al.(2019) Multiple BACE1 inhibitors abnormally increase the BACE1 protein level in neurons by prolonging its half-life.Alzheimers Dement (9):1183−1194. | 2019 | 神経生物学 | |
| Moricz AM, et al.(2019) Distinction and valorization of 30 root extracts of five goldenrod (Solidago) species.J Chromatography A Oct 7 doi: 10.1016/j.chroma.2019.460602. | 2019 | 植物科学 | |
| Napso T, et al.(2019) Advanced maternal age compromises fetal growth and induces sex-specific changes in placental phenotype in rats.Sci Rep 9:16916. | 2019 | その他 | |
| O'Brien CE, et al.(2019) Hypoxia-Ischemia and Hypothermia Independently and Interactively Affect Neuronal Pathology in Neonatal Piglets with Short-Term Recovery.Dev Neurosci 41(1-2):17−33. | 2019 | 神経生物学 | |
| Oh TJ, et al.(2019) TBX3 represses TBX2 under the control of the PRC2 complex in skeletal muscle and rhabdomyosarcoma.Oncogenesis April 12 doi: 10.1038/s41389-019-0137-z. | 2019 | がん | 一般 |
| Oliveira-Mateos C, et al.(2019) The transcribed pseudogene RPSAP52 enhances the oncofetal HMGA2-IGF2BP2-RAS axis through LIN28B-dependent and independent let-7 inhibition.Nat Commun 10(1):3979. | 2019 | がん | 一般 |
| Orlomoski R, et al.(2019) Rapid and efficient purification of Drosophila homeodomain transcription factors for biophysical characterization.Protein Expr Purif 158:9−14. | 2019 | メソッド開発 | |
| Park C, et al.(2019) Species-specific inhibition of antiviral protein kinase R by capripoxviruses and vaccinia virus.Ann NY Acad Sci 1438(1):18−29. | 2019 | 微生物およびモデル生物 | |
| Park SK, et al.(2019) Fucoidan-Rich Substances from Ecklonia cava Improve Trimethyltin-Induced Cognitive Dysfunction via Down-Regulation of Amyloid β Production/Tau Hyperphosphorylation.Mar Drugs 17(10). | 2019 | 神経生物学 | |
| Qiang C, et al.(2019) Flavonoids from Apios americana Medikus Leaves Protect RAW264.7 Cells against Inflammation via Inhibition of MAPKs, Akt-mTOR Pathways, and Nfr2 Activation.Oxid Med Cell Longev 2019:1563024. | 2019 | 細胞シグナル伝達 | |
| Qiao W, et al.(2019) A Novel Effect of Lipids Extracted from Vernix Caseosa on Regulation of Filaggrin Expression in Human Epidermal Keratinocytes.Ann Dermatol 31(6):611−620. | 2019 | その他 | |
| Rageul J, et al.(2019) Conditional degradation of SDE2 by the Arg/N-End rule pathway regulates stress response at replication forks.Nucleic Acids Res Jan 30 ePub:gkz054 | 2019 | その他 | |
| Schultz ML, et al.(2019) Synthetic high-density lipoprotein nanoparticles for the treatment of Niemann-Pick diseases.BMC Med 17(1):200. | 2019 | 神経生物学 | |
| Senthilkumar R, et al.(2019) Synthesis and Evaluation of Anisomelic acid-like Compounds for the Treatment of HPV-Mediated Carcinomas.Sci Rep 9(1):20295. | 2019 | 薬剤機構 | |
| Shi CS, et al.(2019) ARS-Coronavirus Open Reading Frame-8b triggers intracellular stress pathways and activates NLRP3 inflammasomes.Cell Death Discov 5:101. | 2019 | 細胞シグナル伝達 | |
| Subramaniyan SA, et al.(2019) Effect of In Ovo Injection of L-Arginine in Different Chicken Embryonic Development Stages on Post-Hatchability, Immune Response, and Myo-D and Myogenin Proteins.Animals (Basel) Jun 14 doi: 10.3390/ani9060357. | 2019 | その他 | |
| Suzuki H, et al.(2019) Generation of bicistronic reporter knockin mice for visualizing germ layers.Exp Anim 68(4):499−509. | 2019 | メソッド開発 | |
| Tas I, et al.(2019) Inflammatory and tumorigenic effects of environmental pollutants found in particulate matter on lung epithelial cells.Toxicol In Vitro 59:300−311. | 2019 | がん | 肺 |
| Thomson BR, et al.(2019) Targeting the vascular-specific phosphatase PTPRB protects against retinal ganglion cell loss in a pre-clinical model of glaucoma.Elife Oct 17 doi: 10.7554/eLife.48474. | 2019 | その他 | |
| Tsai YH, et al.(2019) Effect of hesperidin on anti-inflammation and cellular antioxidant capacity in hydrogen peroxide-stimulated human articular chondrocytes.Process Biochemistry 85:175−184. | 2019 | その他 | |
| Upadhyay K, et al.(2019) Carbon monoxide releasing molecule-A1 improves nonalcoholic steatohepatitis via Nrf2 activation mediated improvement in oxidative stress and mitochondrial function.Redox Biol 28:10131. | 2019 | Mitochondrial studies | |
| Wang H, et al.(2019) High expression of the transcriptional coactivator TAZ is associated with a worse prognosis and affects cell proliferation in patients with medulloblastoma.Oncol Lett 18(5):5591−5599. | 2019 | がん | 脳 |
| Wang P, et al.(2019) Haspin inhibition delays cell cycle progression through interphase in cancer cells.J Cell Physiol Oct 17 doi: 10.1002/jcp.29328. | 2019 | がん | 一般 |
| Xing M, et al.(2019) Overexpression of p62/IMP2 can Promote Cell Migration in Hepatocellular Carcinoma via Activation of the Wnt/β-Catenin Pathway.Cancers (Basel) 12(1):7. | 2019 | がん | 肝臓 |
| Xuan F, et al.(2019) Wnt/β-catenin signaling contributes to articular cartilage homeostasis through lubricin induction in the superficial zone.Arthritis Res Ther 21:241. | 2019 | 細胞シグナル伝達 | |
| Yi R, et al.(2019) Lactobacillus plantarum CQPC02-Fermented Soybean Milk Improves Loperamide-Induced Constipation in Mice.J Med Food Oct 17 doi: 10.1089/jmf.2019.4467. | 2019 | 微生物およびモデル生物 | |
| Zamboni C, et al.(2019) Cyclin D1 immunohistochemical expression and somatic mutations in canine oral melanoma.Vet Comp Oncol Sep 10 doi: 10.1111/vco.12539. | 2019 | がん | 皮膚 |
| Zamorano-León JJ, et al.(2019) Effect of Pectin on the Expression of Proteins Associated with Mitochondrial Biogenesis and Cell Senescence in HT29-Human Colorectal Adenocarcinoma Cells.Prev Nutr Food Sci 24(2):187−196. | 2019 | がん | 大腸 |
| Zhang J, et al.(2019) Expression and function of Toll like receptors in peripheral blood mononuclear cells in patients with ankylosing spondylitis.Mol Med Rep 20(4):3565−3572. | 2019 | その他 | |
| Zhao K, et al.(2019) TesG Is a type I secretion effector of Pseudomonas aeruginosa that suppresses the host immune response during chronic infection.Nat Microbiol 4(3):459−469. | 2019 | 微生物およびモデル生物 | |
| Zhao X, et al.(2019) Preventive effect of Lactobacillus plantarum KSFY02 isolated from naturally fermented yogurt from Xinjiang, China, on d-galactose-induced oxidative aging in mice.J Dairy Sci 102(7):5899−5912. | 2019 | 微生物およびモデル生物 | |
| Ha JS, et al.(2018) Anti-amyloidogenic properties of an ethyl acetate fraction from Actinidia arguta in Aβ1–42-induced ICR mice.Food Funct 9(6):3264−3277. | 2018 | 神経生物学 | |
| Hirpara J, et al.(2018) Metabolic reprogramming of oncogene-addicted cancer cells to OXPHOS as a mechanism of drug resistance.Redox Biol Dec 17 ePub:101076. | 2018 | がん | 一般 |
| Kelly SC, et al.(2018) Glucose-dependent trans-plasma membrane electron transport and p70S6k phosphorylation in skeletal muscle cells.Redox Biol Dec 12 ePub:101075. | 2018 | 細胞シグナル伝達 | |
| Kim JM, et al.(2018) Ethyl acetate fraction from persimmon (Diospyros kaki) ameliorates cerebral neuronal loss and cognitive deficit via the JNK/Akt pathway in TMT-induced mice.Int J Mol Sci 19:E1499. | 2018 | 神経生物学 | |
| Li J, et al.(2018) Downregulation of Survivin gene expression affects Ionizing radiation resistance of human T98 glioma cells.Cell Mol Neurobiol 38:861–868 | 2018 | がん | 脳 |
| Li J, et al.(2018) MicroRNA 423 promotes proliferation, migration and invasion and induces chemoresistance of endometrial cancer cells.Exp Ther Med 16(5):4213−4224. | 2018 | がん | 子宮内膜 |
| Lin SR, Wen CF (2018) PG-priming enhances doxorubicin influx to trigger necrotic and autophagic cell death in oral squamous cell carcinoma.J Clin Med 7(10):e375. | 2018 | がん | 扁平上皮がん |
| Mishra R, et al.(2018) Can-miRn37a mediated suppression of ethylene response factors enhances the resistance of chilli against anthracnose pathogen Colletotrichum truncatum L. Plant Sci 267:135–147. | 2018 | 植物科学 | |
| Park, SB, et al.(2018) Aruncus dioicus var. kamtschaticus extract suppresses mitochondrial apoptosis induced-neurodegeneration in trimethyltin injected ICR mice.J Food Biochem 42(6):e12667. | 2018 | 神経生物学 | |
| Qian Y, et al.(2018) Lactobacillus plantarum CQPC11 isolated from sichuan pickled cabbages antagonizes d-galactose-induced oxidation and aging in mice.Molecules 23(11):e3026. | 2018 | その他 | |
| Ran L, et al.(2018) Humoral factors contributing to ectopic bone formation induced by medical biomaterials.J Biomater Tissue Eng 8:880–886. | 2018 | その他 | |
| Schultz ML, et al.(2018) Coordinate regulation of mutant NPC1 degradation by selective ER autophagy and MARCH6-dependent ERAD.Nat Commun 9(1):3671. | 2018 | 神経生物学 | |
| Sun Y, et al.(2018) BMAL1 and CLOCK proteins in regulating UVB‐induced apoptosis and DNA damage responses in human keratinocytes.J Cell Physiol 233(12):9563−9574. | 2018 | 細胞シグナル伝達 | |
| Taş I, et al.(2018) Physciosporin suppresses the proliferation, motility and tumourigenesis of colorectal cancer cells.Phytomedicine 56:10-20. | 2018 | がん | 大腸 |
| Thawani A, et al.(2018) XMAP215 Is a microtubule nucleation factor that functions synergistically with the y-tubulin ring complex.Nat Cell Biol 20(5):575−585 | 2018 | 構造生物学／タンパク質相互作用 | |
| Zhang G, et al.(2018) Detection of MiR-29a in plasma patients with lumbar spinal stenosis and the clinical significance.Mol Med Rep 18(1):223−229. | 2018 | 疾病研究：バイオマーカー研究 | |
| Shen P, Chen J, Pan M. (2017) The protective effects of total paeony clycoside on ischemia/reperfusion injury in H9C2 cells via inhibition of the PI3K/Akt signaling pathway.Mol Med Rep 18:3332–3340. | 2017 | 細胞シグナル伝達 | |
.png)
