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Antibiotics are a group of chemicals that are widely used in animal husbandry primarily for protection of animals from disease but also as growth promoters. The European Union (EU) has set maximum residue limits (MRL) for a variety of antibiotics in animal tissues, milk and eggs; suitable methods are required to be capable of detecting these residues at regulated levels. For quantitative analysis it is necessary to use instrumental techniques such as LC-MS/MS. This technique can also be used for screening, and provides much higher sensitivity and greater specificity.
Fluoroquinolones are poly-aromatic compounds with fluorine atoms and carboxylic acid functionality. They are sensitive to silanol interactions with the stationary phase that can lead to compromised peak shape and reduce effective peak resolution.
可変データ非依存 (vDIA) ワークフローによって高感度および高選択性を実現し、測定サンプルの高品質データレコードを取得する方法を示して、動物用医薬品分析の新しいメソッドを説明します。
In a NACRW 2015 interview, Ed George discusses single methodology for the analysis of multi-class veterinary drugs in different animal matrices used for consumption.
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